Blood transfusion risks and alternative strategies in pediatric patients

Paediatric Anaesthesia

Volumn 21, Issue 1, 2011, Pages 14-24

  Lavoie, Josée ^a  

^a MONTREAL CHILDREN S HOSPITAL   (Canada)

Author keywords

acute normovolemic hemodilution; autologous blood donation; blood conservation; blood transfusion; pediatric anesthesia; transfusion related risks

Indexed keywords

ACUTE LUNG INJURY; ALLERGIC REACTION; ALLOIMMUNIZATION; ANAPHYLAXIS; BACTERIUM CONTAMINATION; BLOOD TRANSFUSION; BLOOD TRANSFUSION REACTION; CANADA; CHILDHOOD MORTALITY; DYSPNEA; ERYTHROCYTE PRESERVATION; FRANCE; GRAFT VERSUS HOST REACTION; HEMODILUTION; HEPATITIS B VIRUS; HEPATITIS C VIRUS; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN T CELL LEUKEMIA VIRUS; HYPERTENSION; HYPOTENSION; IMMUNOMODULATION; IRON OVERLOAD; MICROCHIMERISM; MORBIDITY; MORTALITY; PEDIATRIC ANESTHESIA; PRIORITY JOURNAL; PURPURA; REVIEW; SYNCOPE; UNITED KINGDOM; UNITED STATES; URTICARIA;

ACUTE LUNG INJURY; ANTIFIBRINOLYTIC AGENTS; BLOOD LOSS, SURGICAL; BLOOD TRANSFUSION; BLOOD TRANSFUSION, AUTOLOGOUS; CHILD; FEVER; HEMODILUTION; HEMOLYSIS; HUMANS; HYPOTENSION, CONTROLLED; IMMUNOMODULATION; INFECTION; ISOANTIBODIES; OPERATIVE BLOOD SALVAGE; RISK ASSESSMENT;

EID: 78650345332     PISSN: 11555645     EISSN: 14609592     Source Type: Journal    
DOI: 10.1111/j.1460-9592.2010.03470.x     Document Type: Review

References (70)

1. http://msssa4.msss.gouv.qc.ca/fr/document/publication.nsf/ 4b1768b3f849519c852568 fd0061480d/7070b8696d1b0960852576d6004c72e3? OpenDocumentAccessed July 6, 2010.
2. http://www.afssaps.fr/Activites/Hemovigilance/Hemovigilance/(offset)/ 0Accessed July 28, 2010.
3. http://www.shotuk.org/2009-shot-report/ Accessed July 12, 2010.
4. FDA/CBER: Fatalities reported to the FDA following blood collection and transfusion: annual summary for fiscal year 2009. http://www.fda.gov/ BiologicsBloodVac cines/SafetyAvailability/Reporta Problem/ TransfusionDonationFatalities/ucm204763.htmAccessed July 11, 2010.
5. O'Brien SE, Yi Q-L, Scalia V, et al. Current incidence and estimated residual risk of transfusion-transmitted infections in donations made to Canadian Blood Services. Transfusion 2007; 47: 316-325.
6. Blood and transplant matters, issue 29, winter 2009 available at http://www.blood.co.uk/video-audio-leaflets/publications/archive/index. asp#donorbloodmatters Accessed July 12, 2010.
7. Zou S, Dorsey KA, Notari EP, et al. Prevalence, incidence, and residual risk of human immunodeficiency virus and hepatitis C virus infections among United States blood donors since the introduction of nucleic acid testing. Transfusion 2010; 50: 1495-1504.
8. Zou S, Stramer SL, Notari EP, et al. Current incidence and residual risk of hepatitis B infection among blood donors in the United States. Transfusion 2009; 49: 1609-1620.
9. Nübling CM, Heiden M, Chudy M, et al. Experience of mandatory nucleic acid test (NAT) screening across all blood organizations in Germany: NAT yield versus breakthrough transmissions. Transfusion 2009; 49: 1850-1858.
10. Cazenave JP, Waller C, Kientz D, et al. An active hemovigilance program characterizing the safety profile of 7483 transfusions with plasma components prepared with amotosalen and UVA photochemical treatment. Transfusion 2010; 50: 1210-1219.
11. McCullough J, Vesole CH, Benjamin RJ, et al. Therapeutic efficacy and safety of platelets treated with a photochemical process for pathogen inactivation: the SPRINT trial. Blood 2004; 104: 1534-1541.
12. Hendrickson JE, Hillyer CD,. Noninfectious serious hazards of transfusion. Anesth Analg 2009; 108: 759-769.
13. Toy P, Popovsky MA, Abraham E, et al. The National Heart Lung and Blood Institute Working Group on TRALI. Transfusion-related acute lung injury: definition and review. Crit Care Med 2005; 33: 721-726.
14. Wyman TH, Bjornsen AJ, Elzi DJ, et al. A two-insult in vitro model of PMN-mediated pulmonary endothelial damage: requirements for adherence and chemokine release. Am J Physiol Cell Physiol 2002; 283: CI592-CI603.
15. Eder AF, Herron RM Jr, Strupp A, et al. Effective reduction of transfusion-related acute lung injury risk with male-predominant plasma strategy in the American Red Cross. Transfusion 2010; 50: 1732-1742.
16. Mukagatare I, Monfort M, De Marchin J, et al. The effect of leukocyte-reduction on the transfusion reactions to red blood cells concentrates. Transfus Clin Biol 2010; 17: 14-19.
17. Opelz G, Sengar DP, Mickey MR, et al. Effect of blood transfusion on subsequent kidney transplant. Transplant Proc 1973; 5: 253-259.
18. Chang CM, Quinlan SC, Warren JL, et al. Blood transfusions and the subsequent risk of hematologic malignancies. Transfusion 2010; 50: 2249-2257.
19. Vamvakas EC,. White-blood-cell-containing allogeneic blood transfusion and postoperative infection or mortality: an updated meta-analysis. Vox Sang 2007; 92: 224-232.
20. Van De Watering LM, Hermans J, Houbiers JG, et al. Beneficial effects of leukocyte depletion of transfused blood on postoperative complications in patients undergoing cardiac surgery: a randomized clinical trial. Circulation 1998; 97: 562-568.
21. Bilgin YM, Van De Watering LM, Eijsman L, et al. Is increased mortality associated with post-operative infections after leukocytes containing red blood cell transfusions in cardiac surgery? An extended analysis. Transfus Med 2007; 4: 304-311.
22. Stainsby D, Jones H, Wells AW, et al. Adverse outcomes of blood transfusion in children: analysis of UK reports to the serious hazards of transfusion scheme 1996-2005. British Journal of Haematology 2008; 141: 73-79.
23. Bhananker SM, Ramamoorthy C, Geiduschek JM, et al. Anesthesia-related cardiac arrest in children: update from the Pediatric Perioperative Cardiac Arrest registry. Anesth Analg 2007; 105: 344-350.
24. Hans P, Collin V, Bonhomme V, et al. Evaluation of acute normovolemic hemodilution for surgical repair of craniosysnostosis. J Neurosurg Anesthesiol 2000; 12: 33-3614.
25. Joseph SA, Berekashvili K, Mariller MM, et al. Blood conservation techniques in spinal deformity surgery. Spine 2008; 33: 2310-2345.
26. Segal JB, Blasco-Colmenares E, Norris EJ, et al. Preoperative acute normovolemic hemodilution: a meta-analysis. Transfusion. 2004; 44: 632-644.
27. Singbarti K, Schleinzer W, Singbarti G,. Hypervolemic hemodilution: an alternative to acute normovolemic hemodilution? A mathematical analysis J Surg Res 1999; 86: 206-212.
28. Chen YQ, Chen Y, Ji CS, et al. Clinical observation of acute hypervolemic hemodilution in scoliosis surgery on children. Zhonghua Yi Xue Za Shi 2008; 88: 2901-2903.
29. Winter V, Gille J, Richter A, et al. Preoperative hypervolemic hemodilution with 6% hydroxyethyl starch 130/0,4 (HES 130/0,4) solution as a way of reducing needs for donor blood transfusion. Anestheziol Reanimatol 2006; 2: 43-47.
30. Kumar R, Chakraborty I, Sehgal R,. A prospective randomized study comparing two techniques of perioperative blood conservation: isovolemic hemodilution and hypervolemic hemodilution. Anesth Analg 2002; 95: 1154-1161.
31. Degoute CS,. Controlled hypotension: a guide to drug choice. Drugs 2007; 67: 1053-1076.
32. Tobias JD,. Controlled hypotension in children: a critical review of available agents. Paediatr Drugs 2002; 4: 439-453.
33. Choi WS, Samman N,. Risks and benefits of deliberate hypotension in aesthesia: a systematic review. Int J Oral Maxillofac Surg 2008; 37: 687-703.
34. Dolman RM, Bentley KC, Head TW, et al. The effect of hypotensive anesthesia on blood loss and operative time during LeFort 1 osteotomies. J Oral Maxillofac Surg 2000; 58: 834-839.
35. Ragab SM, Hassanin MZ,. Optimizing the surgical field in pediatric functional endoscopic sinus surgery: a new evidence-based approach. Otolaryngol Head Neck Surg 2010; 142: 48-54.
36. Fergusson DA, Hébert PC, Mazer CD, et al. A comparison of aprotinin and lysine analogues in high-risk cardiac surgery. N Engl J Med 2008; 358: 2319-2331.
37. Pasquali SK, Hall M, Li JS, et al. Safety of aprotinin in congenital heart operations: results from a large multicenter database. Ann Thorac Surg 2010; 90: 14-21.
38. Breuer T, Martin K, Wilhelm M, et al. The blood sparing effect and the safety of aprotinin compared to tranexamic acid in paediatric cardiac surgery. Eur J Cardiothorac Surg 2009; 35: 167-171.
39. Tzortzopoulou A, Cepeda MS, Schumann R, et al. Antifibrinolytic agents for reducing blood loss in scoliosis surgery in children. Cochrane Database Syst Rev 2008; 3: 3CD006883.
40. Sethna NF, Zurakowski D, Brustowicz RM, et al. Tranexamic acid reduces intraoperative blood loss in paediatric patients undergoing scoliosis surgery. Anesthesiology 2005; 102: 727-732.
41. Schouten ES, Van De Pol AC, Schouten ANJ, et al. The effect of aprotinin, tranexamic acid, and aminocaproic acid on blood loss and use of blood products in major pediatric surgery: a meta-analysis. Pediatr Crit Care Med 2009; 10: 182-190.
42. Thompson GH, Florentino-Pineda I, Poe-Kochert C, et al. Role of Amicar in surgery for neuromuscular scoliosis. Spine 2008; 33: 2623-2629.
43. Bulutcu FS, Ozbek U, Polat B, et al. Which may be effective to reduce blood loss after cardiac operations in cyanotic children: tranexamic acid, aprotinin or a combination? Paediatr Anesth 2005; 15: 41-46.
44. Carless PA, Henry DA, Moxey AJ, et al. Cell salvage for minimising perioperative allogeneic blood transfusion (Review). Cochrane Database Syst Rev 2010; 4: CD001888.
45. Bowen RE, Gardner S, Scaduto AA, et al. Efficacy of intraoperative cell salvage systems in pediatric idiopathic scoliosis patients undergoing posterior spinal fusion with segmental spinal instrumentation. Spine 2010; 35: 246-251.
46. Mirza AH, Aldlyami E, Bhimarasetty C, et al. The role of peri-operative cell salvage in instrumented anterior correction of thoracolumbar scoliosis: a case-controlled study. Acta Orthop Belg 2009; 75: 87-93.
47. Krajewski K, Ashley RK, Pung N, et al. Successful blood conservation during craniosynostotic correction with dual therapy using procrit and cell saver. J Craniofac Surg 2008; 19: 101-105.
48. Davies L, Brown TJ, Haynes S, et al. Cell salvage and alternative methods of minimising perioperative allogeneic blood transfusion: a systematic review and economic model. Health Technol Assess 2006; 10: 1-210.
49. Feltracco P, Michieletto E, Barbieri S, et al. Microbiologic contamination of intraoperative blood salvaged during liver transplantation. Transpl Proc 2007; 39: 1889-1891.
50. Hibino N, Nagashima M, Sato H, et al. Preoperative autologous blood donation for cardiac surgery in children. Asian Cardiovasc Thorac Ann 2008; 16: 21-24.
51. Rock G, Berger R, Bormanis J, et al. A review of nearly two decades in an autologous blood programme: the rise and fall of activity. Transfus Med 2006; 16: 307-311.
52. Goldman M, Savard R, Long A, et al. Declining value of preoperative autologous donation. Transfusion 2002; 42: 819-823.
53. Lauder GR,. Pre-operative predeposit autologous donation in children presenting for elective surgery: a review. Transfus Med 2007; 17: 75-82.
54. Bess RS, Lenke LG, Bridwell KH, et al. Wasting of preoperatively donated autologous blood in the surgical treatment of adolescent idiopathic scoliosis. Spine 2006; 131: 2375-2380.
55. Singbarti G, Schreiber J, Singbarti K,. Preoperative autologous blood donation versus intraoperative blood salvage: intraindividual analyses and modelling of efficacy in 1103 patients. Transfusion 2009; 49: 2374-2383.
56. Sonzogni V, Crupi G, Poma R, et al. Erythropoietin therapy and preoperative autologous blood donation in children undergoing open heart surgery. Br J Anaesth 2001; 87: 429-434.
57. Regis D, Franchini M, Corallo F, et al. Recombinant human erythropoietin in pediatric patients: efficacy in facilitating autologous blood donation in spinal deformity surgery. Chir Organi Mov 2004; 89: 299-303.
58. Bierer R, Roohi M, Peceny C, et al. Erythropoietin increases reticulocyte counts and maintains hematocrit in neonates requiring surgery. J Pediatr Surg 2009; 44: 1540-1545.
59. Ging AL, St. Onge JR, Fitzgerald DC, et al. Bloodless cardiac surgery and the pediatric patient: a case study. Perfusion 2008; 23: 131-134.
60. Vitale MG, Privitera DM, Matsumoto H, et al. Efficacy of preoperative erythropoietin administration in pediatric neuromuscular scoliosis patients. Spine 2007; 32: 2662-2667.
61. Colomina MJ, Bagà J, Pellisé F, et al. Preoperative erythropoietin in spine surgery. Eur Spine J 2004; 13: S40-S49.
62. Meara JG, Smith EM, Harshbarger RJ, et al. Blood-conservation techniques in craniofacial surgery. Ann Plast Surg 2005; 54: 525-529.
63. Mallett SV, Peachey TC, Sanehi O, et al. Reducing red blood cell transfusion in elective surgical patients: the role of audit and practice guidelines. Anaesthesia 2000; 55: 1013-1019.
64. Lacroix J, Hébert PC, Hutchison JS, et al. Transfusion strategies for patients in pediatric intensive care units. N Engl J Med 2007; 356: 1609-1619.
65. Willems A, Harrington K, Lacroix J, et al. Comparison of two red-cell transfusion strategies after pediatric cardiac surgery: a subgroup analysis. Crit Care Med 2010; 38: 649-656.
66. Rouette J, Trottier H., Ducruet T, Beaunoyer M, Lacroix J, Tucci M,. Red blood cell transfusion threshold in postsurgical pediatric intensive care patients: a randomized clinical trial. Ann Surg 2010; 251: 421-427.
67. Chen HL, Tseng HI, Lu CC, et al. Effect of blood transfusions on the outcome of very low body weight preterm infants under two different transfusion criteria. Pediatr Neonatol 2009; 50: 110-116.
68. Morley SL,. Red blood cell transfusion in acute paediatrics. Arch Dis Child Educ Pract Ed 2009; 94: 65-73.
69. Mozzarelli A, Ronda L, Faggiamo S, et al. Haemoglobin-based oxygen carriers: research and reality towards an alternative to blood transfusions. Blood Transfus 2010; 8: S59-S68.
70. Lapillonne H, Kobari L, Mazurier C, et al. Red blood cells generation from human induced pluripotent stem cells: perspectives for transfusion medicine. Haematologica 2010; 95: 1651-1659.