Red blood cell transfusion threshold in postsurgical pediatric intensive care patients: A randomized clinical trial

Annals of Surgery

Volumn 251, Issue 3, 2010, Pages 421-427

  Rouette, Justine ^a   Trottier, Helen ^a   Ducruet, Thierry ^a   Beaunoyer, Mona ^a   Lacroix, Jacques ^a   Tucci, Marisa ^a  

^a UNIVERSITY OF MONTREAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

HEMOGLOBIN;

ARTICLE; ARTIFICIAL VENTILATION; CHILD; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; ERYTHROCYTE TRANSFUSION; FEMALE; HUMAN; INTENSIVE CARE UNIT; MAJOR CLINICAL STUDY; MALE; MORTALITY; MULTICENTER STUDY; OUTCOME ASSESSMENT; PEDIATRIC SURGERY; POSTOPERATIVE PERIOD; PRESCHOOL CHILD; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RISK REDUCTION; SURGICAL PATIENT;

EID: 77649089003     PISSN: 00034932     EISSN: 15281140     Source Type: Journal    
DOI: 10.1097/SLA.0b013e3181c5dc2e     Document Type: Article

References (28)

1. Hebert PC, Wells G, Blajchman MA, et al; Canadian Critical Care Trials Group. A multicenter, randomized, controlled clinical trial of transfusion requirements in critical care. Transfusion requirements in critical care investigators. N Engl J Med. 1999;340:409-417.
2. Bateman ST, Lacroix J, Boven K, et al. Anemia, blood loss, and blood transfusion in North American children in the intensive care unit. Am J Respir Crit Care Med. 2008;178:26-33.
3. Hajjar LA, Auler Junior JO, Santos L, et al. Blood transfusion in critically ill patients: state of the art. Clinics. 2007;62:507-524.
4. Tinmouth AT, McIntyre LA, Fowler RA. Blood conservation strategies to reduce the need for red blood cell transfusion in critically ill patients. CMAJ. 2008;178:49-57.
5. Napolitano LM, Corwin HL. Efficacy of red blood cell transfusion in the critically ill. Crit Care Clin. 2004;20:255-268.
6. Lacroix J, Hébert PC, Hutchison JS, et al. Transfusion strategies for patients in pediatric intensive care units. N Engl J Med. 2007;356:1609-1619.
7. Laverdière C, Gauvin F, Hébert PC, et al. Survey on transfusion practices of pediatric intensivists. Pediatr Crit Care Med. 2002;3:335-340.
8. Armano R, Gauvin F, Ducruet T, et al. Determinants of red blood cell transfusions in a pediatric critical care unit: a prospective, descriptive epide-miological study. Crit Care Med. 2005;33:2637-2644.
9. Proulx F, Fayon M, Farrell CA, et al. Epidemiology of sepsis and multiple organ dysfunction syndrome in children. Chest. 1996;109:1033-1037.
10. Leteurtre S, Martinot A, Duhamel A, et al. Validation of the paediatric logistic organ dysfunction (PELOD) score: prospective, observational, mul-ticentre study. Lancet. 2003;362:192-197.
11. CDC definitions for nosocomial infections, 1988. Am Rev Respir Dis. 1989; 139:1058-1059.
12. Pollack MM, Ruttimann UE, Getson PR. Pediatric risk of mortality (PRISM) score. Crit Care Med. 1988;16:1110-1116.
13. Bennett-Guerrero E, Veldman TH, Doctor A, et al. Evolution of adverse changes in stored RBCs. Proc Natl Acad Sci USA. 2007;104:17063-17068.
14. Gauvin F, Lacroix J, Robillard P, et al. Acute transfusion reactions in the pediatric intensive care unit. Transfusion. 2006;46:1899-1908.
15. Vamvakas EC. Deleterious clinical effects of transfusion immunomodulation: proven beyond a reasonable doubt. Transfusion. 2006;46:492-494.
16. Vamvakas EC. Transfusion-related immunomodulation (TRIM): an update. Blood Rev. 2007;21:327-348.
17. Doctor A, Platt R, Sheram ML, et al. Hemoglobin conformation couples erythrocyte S-nitrosothiol content to O2 gradients. Proc Natl Acad Sci USA. 2005;102:5709-5714.
18. Hill GE, Frawley WH, Griffith KE, et al. Allogenic blood transfusion increases the risk of postoperative bacterial infection: a meta-analysis. J Trauma. 2003;54:908-914.
19. Adams C, Biffl WL, Cioffi WG. Surgical critical care. In: Townsend CM, Beauchamp RD, Evers BM, et al, eds. Townsend: Sabiston Textbook of Surgery. 18th ed. Philadelphia, PA: Elsevier; 2007.
20. Schwartz D, Kaplan KL, Schwartz SI. Hemostasis, surgical bleeding, and transfusion. In: Brunicardi RC, Andersen DK, Billiarn TK. Schwartz's Principles of Surgery. 8th ed. New York City, NY: McGraw-Hill; 2005
21. American Association of Anasthesiologists Task Force on Perioperative Blood Transfusion and Adjuvant Therapies. Practice guidelines for perioper-ative blood transfusion and adjuvant therapies. Anesthesiology. 2006;105: 198-208.
22. Basora M, Colomina MJ, Moral V, et al. Descriptive study of perioperative transfusion practices in Spanish hospitals. Transfus Altern Transfus Med. 2008;10:9-16.
23. Corwin HL, Gettinger A, Pearl RG, et al. The CRIT study: anemia and blood transfusion in the critically ill-current clinical practice in the United States. Crit Care Med. 2004;32:39-52.
24. Carson JL, Terrin ML, Barton FB, et al. A pilot randomized trial comparing symptomatic vs. hemoglobin-level-driven red blood cell transfusions following hip fracture. Transfusion. 1998;38:522-529.
25. Wang R, Lagakos SW, Ware JH, et al. Statistics in medicine-reporting of subgroup analyses in clinical trials. N Engl J Med. 2007;357:2189-2194.
26. Oxman AD, Guyatt GH. A consumer's guide to subgroup analyses. Ann Intern Med. 1992;116:78-84.
27. Soliman DR, Cassara A. Special surgical management: pediatrics. In: Waters JH, ed. Blood Management: Options for Better Patient Care. Bethesda, MD: AABB Press; 2008:395-422.
28. Gibson BE, Todd A, Roberts I, et al. Transfusion guidelines for neonates and older children. Br J Haematol. 2004;124:433-453.