The xenotropic murine leukemia virus-related retrovirus debate continues at first international workshop

Retrovirology

Volumn 7, Issue , 2010, Pages

  Stoye, Jonathan P ^a   Silverman, Robert H ^b   Boucher, Charles A ^c   Le Grice, Stuart F J ^d  

^a NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

^b LERNER RESEARCH INSTITUTE   (United States)

^c ERASMUS MEDICAL CENTER   (Netherlands)

^d NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHRONIC FATIGUE SYNDROME; GENE AMPLIFICATION; GENE MUTATION; HUMAN; IMMUNE RESPONSE; IMMUNOHISTOCHEMISTRY; NONHUMAN; PROSTATE CANCER; RETROVIRUS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; REVIEW; SEROLOGY; SOUTHERN BLOTTING; VIRUS CARCINOGENESIS; VIRUS CELL INTERACTION; VIRUS CULTURE; VIRUS REPLICATION; WORKSHOP; XENOTROPIC MULV RELATED VIRUS; ANIMAL; CONFERENCE PAPER; FEMALE; GENETICS; HOST PATHOGEN INTERACTION; ISOLATION AND PURIFICATION; MALE; METABOLISM; PHYSIOLOGY; PROSTATE TUMOR; RETROVIRUS INFECTION; VIROLOGY;

GAMMARETROVIRUS; XENOTROPIC MURINE LEUKEMIA VIRUS;

ANIMALS; FATIGUE SYNDROME, CHRONIC; FEMALE; HOST-PATHOGEN INTERACTIONS; HUMANS; MALE; PROSTATIC NEOPLASMS; RETROVIRIDAE; RETROVIRIDAE INFECTIONS; XENOTROPIC MURINE LEUKEMIA VIRUS-RELATED VIRUS;

EID: 78650335600     PISSN: None     EISSN: 17424690     Source Type: Journal    
DOI: 10.1186/1742-4690-7-113     Document Type: Review

References (31)

1. Urisman A, Molinaro RJ, Fischer N, Plummer SJ, Casey G, Klein EA, Malathi K, Magi-Galluzzi C, Tubbs RR, Ganem D, et al. Identification of a novel Gammaretrovirus in prostate tumors of patients homozygous for R462Q RNASEL variant. PLoS Pathog 2006, 2:e25. 10.1371/journal.ppat.0020025, 1434790, 16609730.
2. Schlaberg R, Choe DJ, Brown KR, Thaker HM, Singh IR. XMRV is present in malignant prostatic epithelium and is associated with prostate cancer, especially high-grade tumors. Proc Natl Acad Sci USA 2009, 106:16351-16356. 10.1073/pnas.0906922106, 2739868, 19805305.
3. Lombardi VC, Ruscetti FW, Das Gupta J, Pfost MA, Hagen KS, Peterson DL, Ruscetti SK, Bagni RK, Petrow-Sadowski C, Gold B, et al. Detection of an infectious retrovirus, XMRV, in blood cells of patients with chronic fatigue syndrome. Science 2009, 326:585-589. 10.1126/science.1179052, 19815723.
4. Arnold RS, Makarova NV, Osunkoya AO, Suppiah S, Scott TA, Johnson NA, Bhosle SM, Liotta D, Hunter E, Marshall FF, et al. XMRV infection in patients with prostate cancer: novel serologic assay and correlation with PCR and FISH. Urology 2010, 75:755-761. 10.1016/j.urology.2010.01.038, 20371060.
5. Danielson BP, Ayala GE, Kimata JT. Detection of xenotropic murine leukemia virus-related virus in normal and tumor tissue of patients from the southern United States with prostate cancer is dependent on specific polymerase chain reaction conditions. J Infect Dis 2010, 202:1470-1477. 10.1086/656146, 20936978.
6. Fischer N, Schulz C, Stieler K, Hohn O, Lange C, Drosten C, Aepfelbacher M. Xenotropic murine leukemia virus-related gammaretrovirus in respiratory tract. Emerg Infect Dis 2010, 16:1000-1002.
7. Aloia AL, Sfanos KS, Isaacs WB, Zheng Q, Maldarelli F, De Marzo AM, Rein A. XMRV: A New Virus in Prostate Cancer?. Cancer Res 2010,
8. Barnes E, Flanagan P, Brown A, Robinson N, Brown H, McClure M, Oxenius A, Collier J, Weber J, Gunthard HF, et al. Failure to detect xenotropic murine leukemia virus-related virus in blood of individuals at high risk of blood-borne viral infections. J Infect Dis 2010, 202:1482-1485. 10.1086/657167, 20936982.
9. Cornelissen M, Zorgdrager F, Blom P, Jurriaans S, Repping S, van Leeuwen E, Bakker M, Berkhout B, van der Kuyl AC. Lack of detection of XMRV in seminal plasma from HIV-1 infected men in The Netherlands. PLoS One 2010, 5:e12040. 10.1371/journal.pone.0012040, 2919391, 20706581.
10. Erlwein O, Kaye S, McClure MO, Weber J, Wills G, Collier D, Wessely S, Cleare A. Failure to detect the novel retrovirus XMRV in chronic fatigue syndrome. PLoS One 2010, 5:e8519. 10.1371/journal.pone.0008519, 2795199, 20066031.
11. Groom HC, Boucherit VC, Makinson K, Randal E, Baptista S, Hagan S, Gow JW, Mattes FM, Breuer J, Kerr JR, et al. Absence of xenotropic murine leukaemia virus-related virus in UK patients with chronic fatigue syndrome. Retrovirology 2010, 7:10. 10.1186/1742-4690-7-10, 2839973, 20156349.
12. Hohn O, Krause H, Barbarotto P, Niederstadt L, Beimforde N, Denner J, Miller K, Kurth R, Bannert N. Lack of evidence for xenotropic murine leukemia virus-related virus(XMRV) in German prostate cancer patients. Retrovirology 2009, 6:92. 10.1186/1742-4690-6-92, 2770519, 19835577.
13. Hong P, Li J, Li Y. Failure to detect Xenotropic murine leukaemia virus-related virus in Chinese patients with chronic fatigue syndrome. Virol J 2010, 7:224. 10.1186/1743-422X-7-224, 2945957, 20836869.
14. Jeziorski E, Foulongne V, Ludwig C, Louhaem D, Chiocchia G, Segondy M, Rodiere M, Sitbon M, Courgnaud V. No evidence for XMRV association in pediatric idiopathic diseases in France. Retrovirology 2010, 7:63. 10.1186/1742-4690-7-63, 2920251, 20678193.
15. Switzer WM, Jia H, Hohn O, Zheng H, Tang S, Shankar A, Bannert N, Simmons G, Hendry RM, Falkenberg VR, et al. Absence of evidence of xenotropic murine leukemia virus-related virus infection in persons with chronic fatigue syndrome and healthy controls in the United States. Retrovirology 2010, 7:57. 10.1186/1742-4690-7-57, 2908559, 20594299.
16. Kim S, Kim N, Dong B, Boren D, Lee SA, Das Gupta J, Gaughan C, Klein EA, Lee C, Silverman RH, Chow SA. Integration site preference of xenotropic murine leukemia virus-related virus, a new human retrovirus associated with prostate cancer. J Virol 2008, 82:9964-9977. 10.1128/JVI.01299-08, 2566297, 18684813.
17. Kim S, Rusmevichientong A, Dong B, Remenyi R, Silverman RH, Chow SA. Fidelity of target site duplication and sequence preference during integration of xenotropic murine leukemia virus-related virus. PLoS One 2010, 5:e10255. 10.1371/journal.pone.0010255, 2857682, 20421928.
18. Lueders KK, Kuff EL. Sequences associated with intracisternal A particles are reiterated in the mouse genome. Cell 1977, 12:963-972. 10.1016/0092-8674(77)90161-1, 597866.
19. Dong B, Silverman RH. Androgen stimulates transcription and replication of xenotropic murine leukemia virus-related virus. J Virol 2010, 84:1648-1651. 10.1128/JVI.01763-09, 2812331, 19906923.
20. Groom HC, Yap MW, Galao RP, Neil SJ, Bishop KN. Susceptibility of xenotropic murine leukemia virus-related virus (XMRV) to retroviral restriction factors. Proc Natl Acad Sci USA 2010, 107:5166-5171. 10.1073/pnas.0913650107, 2841911, 20194752.
21. Qiu X, Swanson P, Luk KC, Tu B, Villinger F, Das Gupta J, Silverman RH, Klein EA, Devare S, Schochetman G, Hackett J. Characterization of antibodies elicited by XMRV infection and development of immunoassays useful for epidemiologic studies. Retrovirology 2010, 7:68. 2931451, 20716359.
22. Yan Y, Liu Q, Kozak CA. Six host range variants of the xenotropic/polytropic gammaretroviruses define determinants for entry in the XPR1 cell surface receptor. Retrovirology 2009, 6:87. 10.1186/1742-4690-6-87, 2768677, 19811656.
23. Baliji S, Liu Q, Kozak CA. Common inbred strains of the laboratory mouse that are susceptible to infection by mouse xenotropic gammaretroviruses and the human derived XMRV. J Virol 2010,
24. Yan Y, Liu Q, Wollenberg K, Martin C, Buckler-White A, Kozak CA. Evolution of functional and sequence variants of the mammalian XPR1 receptor for mouse xenotropic gammaretroviruses and the human-derived retrovirus XMRV. J Virol 2010, 84:11970-11980. 10.1128/JVI.01549-10, 20844050.
25. Sakuma T, Tonne JM, Squillace KA, Ohmine S, Thatava T, Peng KW, Barry MA, Ikeda Y. Early Events in XMRV infection of wild-derived mouse, Mus pahari. J Virol 2010,
26. Carpten J, Nupponen N, Isaacs S, Sood R, Robbins C, Xu J, Faruque M, Moses T, Ewing C, Gillanders E, et al. Germline mutations in the ribonuclease L gene in families showing linkage with HPC1. Nat Genet 2002, 30:181-184. 10.1038/ng823, 11799394.
27. Casey G, Neville PJ, Plummer SJ, Xiang Y, Krumroy LM, Klein EA, Catalona WJ, Nupponen N, Carpten JD, Trent JM, et al. RNASEL Arg462Gln variant is implicated in up to 13% of prostate cancer cases. Nat Genet 2002, 32:581-583. 10.1038/ng1021, 12415269.
28. Knouf EC, Metzger MJ, Mitchell PS, Arroyo JD, Chevillet JR, Tewari M, Miller AD. Multiple integrated copies and high-level production of the human retrovirus XMRV (xenotropic murine leukemia virus-related virus) from 22Rv1 prostate carcinoma cells. J Virol 2009, 83:7353-7356. 10.1128/JVI.00546-09, 2704771, 19403664.
29. Singh IR, Gorzynski JE, Drobysheva D, Bassit L, Schinazi RF. Raltegravir is a potent inhibitor of XMRV, a virus implicated in prostate cancer and chronic fatigue syndrome. PLoS One 2010, 5:e9948. 10.1371/journal.pone.0009948, 2848589, 20376347.
30. Fischer N, Hellwinkel O, Schulz C, Chun FK, Huland H, Aepfelbacher M, Schlomm T. Prevalence of human gammaretrovirus XMRV in sporadic prostate cancer. J Clin Virol 2008, 43:277-283. 10.1016/j.jcv.2008.04.016, 18823818.
31. Lo SC, Pripuzova N, Li B, Komaroff AL, Hung GC, Wang R, Alter HJ. Detection of MLV-related virus gene sequences in blood of patients with chronic fatigue syndrome and healthy blood donors. Proc Natl Acad Sci 2010, 107:15874-15879. 10.1073/pnas.1006901107, 20798047.