Pd-NHC catalyzed cyclopentannulation of diazabicyclic alkenes with ortho -aryl halides

Organic Letters

Volumn 12, Issue 23, 2010, Pages 5422-5425

  Prasad, B A Bhanu ^a   Buechele, Alexander E ^a   Gilbertson, Scott R ^a  

^a University of Houston   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 78650326847     PISSN: 15237060     EISSN: 15237052     Source Type: Journal    
DOI: 10.1021/ol102270r     Document Type: Article

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40. Use of stronger base such as NaH or KOtBu, diazabicyclic alkene and iodophenol underwent decomposition and gave only trace amount of 4i. However, use of DIPEA as a base the ring-opened 7d was observed as a major product along with the desired cyclised product 4i.