N-Acetyltransferase 2 polymorphisms and susceptibility to infant leukemia with maternal exposure to dipyrone during pregnancy

Cancer Epidemiology Biomarkers and Prevention

Volumn 19, Issue 12, 2010, Pages 3037-3043

  Zanrosso, Crisiane Wais ^a,c   Emerenciano, Mariana ^a   De Aguiar Gonçalves, Bruno Alves ^a   Faro, Alessandra ^a   Koifman, Sérgio ^b   Pombo de Oliveira, Maria S ^a  

^a INSTITUTO NACIONAL DE CÂNCER   (Brazil)

^b INSTITUTO OSWALDO CRUZ   (Brazil)

^c UNIVERSITY OF CAXIAS DO SUL   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

ARYLAMINE ACETYLTRANSFERASE; DIPYRONE;

ACETYLATION; ADOLESCENT; ADULT; ARTICLE; CANCER RISK; CANCER SUSCEPTIBILITY; CHILD; CHILDHOOD LEUKEMIA; CONTROLLED STUDY; FEMALE; GENE; GENETIC POLYMORPHISM; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; GENOTYPE; HAPLOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; NAT2 GENE; POLYMERASE CHAIN REACTION; PRENATAL EXPOSURE; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM;

ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ARYLAMINE N-ACETYLTRANSFERASE; DIPYRONE; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; IN SITU HYBRIDIZATION; INFANT; INFANT, NEWBORN; LEUKEMIA; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; POLYMORPHISM, SINGLE NUCLEOTIDE; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 78650321891     PISSN: 10559965     EISSN: None     Source Type: Journal    
DOI: 10.1158/1055-9965.EPI-10-0508     Document Type: Article

References (20)

1. Ross JA. Environmental and genetic susceptibility to MLL-defined infant leukemia. J Natl Cancer Inst Monogr 2008;39:83-6.
2. Ford AM, Ridge SA, Cabrera ME, et al. . In utero rearrangements in the trithorax-related oncogene in infant leukaemias. Nature 1993;363:358-60.
3. Harper DP, Aplan PD. Chromosomal rearrangements leading to MLL gene fusions: clinical and biological aspects. Cancer Res 2008;68:10024-7.
4. Alexander FE, Patheal SL, Biondi A, et al. . Transplacental chemical exposure and risk of infant leukemia with MLL gene fusion. Cancer Res 2001;61:2542-6.
5. Pombo-de-Oliveira MS, Koifman S. Infant acute leukemia and maternal exposures during pregnancy. Cancer Epidemiol Biomarkers Prev 2006;15:2336-41.
6. Sharpe CR, Franco EL, Brazilian Wilms' Tumor Study Group. Use of dipyrone during pregnancy and risk of Wilms' tumor. Epidemiology 1996;7:533-5.
7. Perera FP, Jedrychowski W, Rauh V, Whyatt RM. Molecular epidemiologic research on the effects of environmental pollutants on the fetus. Environ Health Perspect 1999;107Suppl 3:451-60.
8. Geisslinger G, Bocker R, Levy M. High-performance liquid chromatographic analysis of dipyrone metabolites to study their formation in human liver microsomes. Pharm Res 1996;13:1272-5.
9. Krajinovic M, Richer C, Sinnett H, Labuda D, Sinnett D. Genetic polymorphisms of N-acetyltransferases 1 and 2 and gene-gene interaction in the susceptibility to childhood acute lymphoblastic leukemia. Cancer Epidemiol Biomarkers Prev 2000;9:557-62.
10. Emerenciano M, Agudelo Arias DP, Coser VM, de Brito GD, Macedo-Silva ML, Pombo-de-Oliveira MS. Molecular cytogenetic findings of acute leukemia included in the Brazilian Collaborative Study Group of Infant acute leukemia. Pediatr Blood Cancer 2005;47:549-54.
11. Cascorbi I, Brockmoller J, Mrozikiewicz PM, Bauer S, Loddenkemper R, Roots I. Homozygous rapid arylamine N-acetyltransferase (NAT2) genotype as a susceptibility factor for lung cancer. Cancer Res 1996;56:3961-6.
12. Vatsis KP, Weber WW, Bell DA, et al. . Nomenclature for N-acetyl-transferases. Pharmacogenetics 1995;5:1-17.
13. Consensus Human Arylamine N-Acetyltransferase Gene Nomenclature [Internet]. Paris: University of Louisville School of Medicine; [updated 2010 March 17; cited 2010 June 14]. Available from: http://N- acetyltransferasenomenclature.louisville.edu
14. Krajinovic M, Sinnett H, Richer C, Labuda D, Sinnett D. Role of NQO1, MPO and CYP2E1 genetic polymorphisms in the susceptibility to childhood acute lymphoblastic leukemia. Int J Cancer 2002;97:230-6.
15. Sinnett D, Krajinovic M, Labuda D. Genetic susceptibility to childhood acute lymphoblastic leukemia. Leuk Lymphoma 2000;38:447-62. (Pubitemid 30614530)
16. Garcia-Martin E. Interethnic and intraethnic variability of NAT2 single nucleotide polymorphisms. Curr Drug Metab 2008;9:487-97. (Pubitemid 352034203)
17. Alcorn J, McNamara PJ. Ontogeny of hepatic and renal systemic clearance pathways in infants: part I. Clin Pharmacokinet 2002;41:959-98.
18. Paulsen JE, Steffensen IL, Namork E, Hein DW, Alexander J. Effect of acetylator genotype on 3,2-dimethyl-4-aminobiphenyl induced aberrant crypt foci in the colon hamsters. Carcinogenesis 1996;17:459-65.
19. Derewlany LO, Koren G. Biotransformation of carcinogenic arylamines and arylamides by human placenta. J Lab Clin Med 1994;124:134-41. (Pubitemid 2125691)
20. Hargis JB, La Russa V, Redmond J, Kessler SW, Wright DG. Agranulocytosis associated with "Mexican aspirin" (dipyrone): evidence for an autoimmune mechanism affecting multipotential hematopoietic progenitors. Am J Hematol 1989;31:213-5.