Associations between intracranial haemorrhage and prescribed prophylaxis in a large cohort of haemophilia patients in the United States

British Journal of Haematology

Volumn 152, Issue 2, 2011, Pages 211-216

  Witmer, Char ^a   Presley, Rodney ^b   Kulkarni, Roshni ^b,c   Michael Soucie, J ^b   Manno, Catherine S ^d   Raffini, Leslie ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b NATIONAL CENTER ON BIRTH DEFECTS AND DEVELOPMENTAL DISABILITIES   (United States)

^c MICHIGAN STATE UNIVERSITY   (United States)

^d NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Haemophilia; Head trauma; Intracranial haemorrhage; Prophylaxis; Risk factors

Indexed keywords

ACTIVATED PROTHROMBIN COMPLEX; BLOOD CLOTTING FACTOR 8 INHIBITOR; RECOMBINANT BLOOD CLOTTING FACTOR 8; RECOMBINANT BLOOD CLOTTING FACTOR 9;

ADOLESCENT; ADULT; ARTICLE; BRAIN HEMORRHAGE; CASE CONTROL STUDY; CHILD; COHORT ANALYSIS; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE SEVERITY; DISEASE SURVEILLANCE; HEAD INJURY; HEMOPHILIA; HEMOPHILIA A; HEMOPHILIA B; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS; MAJOR CLINICAL STUDY; MALE; MORBIDITY; PRESCHOOL CHILD; PRESCRIPTION; PRIORITY JOURNAL; PROTECTION; RISK FACTOR; RISK REDUCTION; SCHOOL CHILD; UNITED STATES;

ADOLESCENT; ADULT; AGE DISTRIBUTION; CASE-CONTROL STUDIES; CEREBRAL HEMORRHAGE; CHILD; CHILD, PRESCHOOL; CRANIOCEREBRAL TRAUMA; FACTOR IX; FACTOR VIII; HEMOPHILIA A; HEMOPHILIA B; HUMANS; MALE; RISK FACTORS; UNITED STATES; YOUNG ADULT;

EID: 78650316037     PISSN: 00071048     EISSN: 13652141     Source Type: Journal    
DOI: 10.1111/j.1365-2141.2010.08469.x     Document Type: Article

References (18)

1. Andes, W.A., Wulff, K. & Smith, W.B. (1984) Head trauma in hemophilia. A prospective study. Archives of Internal Medicine, 144, 1981-1983.
2. Antunes, S.V., Vicari, P., Cavalheiro, S. & Bordin, J.O. (2003) Intracranial haemorrhage among a population of haemophilic patients in Brazil. Haemophilia, 9, 573-577.
3. CDC (2002) Report on the Universal Data Collection Program., Vol. 4, pp. 1-26. CDC, Atlanta, GA.
4. CDC (2003) Blood safety monitoring among persons with bleeding disorders-United States, May 1998-June 2002. In: Morb Mortal Wkly Rep, Vol. 51, pp. 1152-1154.
5. Chorba, T.L., Holman, R.C., Strine, T.W., Clarke, M.J. & Evatt, B.L. (1994) Changes in longevity and causes of death among persons with hemophilia A. American Journal of Hematology, 45, 112-121.
6. Eyster, M.E., Gill, F.M., Blatt, P.M., Hilgartner, M.W., Ballard, J.O. & Kinney, T.R. (1978) Central nervous system bleeding in hemophiliacs. Blood, 51, 1179-1188.
7. Hay, C.R. (2007) Prophylaxis in adults with haemophilia. Haemophilia, 13(Suppl 2), 10-15.
8. Klinge, J., Auberger, K., Auerswald, G., Brackmann, H.H., Mauz-Korholz, C. & Kreuz, W. (1999) Prevalence and outcome of intracranial haemorrhage in haemophiliacs - a survey of the paediatric group of the German Society of Thrombosis and Haemostasis (GTH). European Journal of Pediatrics, 158(Suppl. 3), S162-S165.
9. Kulkarni, R., Soucie, J.M., Lusher, J., Presley, R., Shapiro, A., Gill, J., Manco-Johnson, M., Koerper, M., Mathew, P., Abshire, T., Dimichele, D., Hoots, K., Janco, R., Nugent, D., Geraghty, S. & Evatt, B. (2009) Sites of initial bleeding episodes, mode of delivery and age of diagnosis in babies with haemophilia diagnosed before the age of 2 years: a report from The Centers for Disease Control and Prevention's (CDC) Universal Data Collection (UDC) project. Haemophilia, 15, 1281-1290.
10. Ljung, R.C. (2008) Intracranial haemorrhage in haemophilia A and B. British Journal Haematology, 140, 378-384.
11. Manco-Johnson, M.J., Abshire, T.C., Shapiro, A.D., Riske, B., Hacker, M.R., Kilcoyne, R., Ingram, J.D., Manco-Johnson, M.L., Funk, S., Jacobson, L., Valentino, L.A., Hoots, W.K., Buchanan, G.R., DiMichele, D., Recht, M., Brown, D., Leissinger, C., Bleak, S., Cohen, A., Mathew, P., Matsunaga, A., Medeiros, D., Nugent, D., Thomas, G.A., Thompson, A.A., McRedmond, K., Soucie, J.M., Austin, H. & Evatt, B.L. (2007) Prophylaxis versus episodic treatment to prevent joint disease in boys with severe hemophilia. New England Journal of Medicine, 357, 535-544.
12. Nuss, R., Soucie, J.M. & Evatt, B. (2001) Changes in the occurrence of and risk factors for hemophilia-associated intracranial hemorrhage. American Journal of Hematology, 68, 37-42.
13. Revel-Vilk, S., Golomb, M.R., Achonu, C., Stain, A.M., Armstrong, D., Barnes, M.A., Anderson, P., Logan, W.J., Sung, L., McNeely, M., Blanchette, V. & Feldman, B.M. (2004) Effect of intracranial bleeds on the health and quality of life of boys with hemophilia. Journal of Pediatrics, 144, 490-495.
14. Soucie, J.M., Evatt, B. & Jackson, D. (1998) Occurrence of hemophilia in the United States. The Hemophilia Surveillance System Project Investigators. American Journal of Hematology, 59, 288-294.
15. Soucie, J.M., Cianfrini, C., Janco, R.L., Kulkarni, R., Hambleton, J., Evatt, B., Forsyth, A., Geraghty, S., Hoots, K., Abshire, T., Curtis, R., Forsberg, A., Huszti, H., Wagner, M. & White, II, G.C. (2004) Joint range-of-motion limitations among young males with hemophilia: prevalence and risk factors. Blood, 103, 2467-2473.
16. Stieltjes, N., Calvez, T., Demiguel, V., Torchet, M.F., Briquel, M.E., Fressinaud, E., Claeyssens, S., Coatmelec, B. & Chambost, H. (2005) Intracranial haemorrhages in French haemophilia patients (1991-2001): clinical presentation, management and prognosis factors for death. Haemophilia, 11, 452-458.
17. de Tezanos Pinto, M., Fernandez, J. & Perez Bianco, P.R. (1992) Update of 156 episodes of central nervous system bleeding in hemophiliacs. Haemostasis, 22, 259-267.
18. Traivaree, C., Blanchette, V., Armstrong, D., Floros, G., Stain, A.M. & Carcao, M.D. (2007) Intracranial bleeding in haemophilia beyond the neonatal period--the role of CT imaging in suspected intracranial bleeding. Haemophilia, 13, 552-559.