Human dopamine β-hydroxylase promoter variant alters transcription in chromaffin cells, enzyme secretion, and blood pressure

American Journal of Hypertension

Volumn 24, Issue 1, 2011, Pages 24-32

  Chen, Yuqing ^a,b   Zhang, Kuixing ^a   Wen, Gen ^a   Rao, Fangwen ^a   Sanchez, Amber P ^a   Wang, Lei ^a   Rodriguez Flores, Juan L ^a   Mahata, Manjula ^a   Mahata, Sushil K ^a,c   Waalen, Jill ^d   Ziegler, Michael G ^a   Hamilton, Bruce A ^a   O'Connor, Daniel T ^a,c,e  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b PEKING UNIVERSITY FIRST HOSPITAL   (China)

^c VA SAN DIEGO HEALTHCARE SYSTEM   (United States)

^d SCRIPPS RESEARCH INSTITUTE   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

blood pressure; dopamine hydroxylase; hypertension; polymorphism

Indexed keywords

DOPAMINE BETA MONOOXYGENASE; HYPOPHYSIS ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE; LUCIFERASE; NICOTINE; PROTEIN C FOS;

AMINO ACID SEQUENCE; ARTICLE; BLOOD PRESSURE; CARDIOVASCULAR RISK; CHROMAFFIN CELL; CHROMATIN IMMUNOPRECIPITATION; DIASTOLIC BLOOD PRESSURE; ENZYME ACTIVITY; ENZYME RELEASE; FEMALE; GENE ACTIVITY; GENE FREQUENCY; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; GENETIC VARIABILITY; HAPLOTYPE; HUMAN; MALE; PLASMID; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN MOTIF; SINGLE NUCLEOTIDE POLYMORPHISM; SITE DIRECTED MUTAGENESIS; SPECTROPHOTOMETRY;

ANIMALS; BLOOD PRESSURE; CHROMAFFIN CELLS; DOPAMINE BETA-HYDROXYLASE; FEMALE; GENES, FOS; HAPLOTYPES; HUMANS; HYPERTENSION; MALE; PC12 CELLS; POLYMORPHISM, SINGLE NUCLEOTIDE; PROMOTER REGIONS, GENETIC; RATS; TRANSCRIPTION, GENETIC;

EID: 78650292756     PISSN: 08957061     EISSN: None     Source Type: Journal    
DOI: 10.1038/ajh.2010.186     Document Type: Article

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