XRCC1 deficiency sensitizes human lung epithelial cells to genotoxicity by crocidolite asbestos and Libby amphibole

Environmental Health Perspectives

Volumn 118, Issue 12, 2010, Pages 1707-1713

  Pietruska, Jodie R ^a   Johnston, Tatiana ^a   Zhitkovich, Anatoly ^a   Kane, Agnes B ^a  

^a BROWN UNIVERSITY   (United States)

Author keywords

Asbestos; Crocidolite; DNA breaks; DNA repair; Libby amphibole; Micronuclei; Nuclear buds; XRCC1

Indexed keywords

AMPHIBOLE; BLEOMYCIN; CALCIUM SILICATE; CROCIDOLITE; DNA; HYDROGEN PEROXIDE; PACLITAXEL; PROTEIN P53; TITANIUM DIOXIDE; XRCC1 PROTEIN;

ARTICLE; CELL PROTECTION; CHROMOSOME ABERRATION; CHROMOSOME BREAKAGE; CONTROLLED STUDY; CYTOTOXICITY; DNA DAMAGE; EXPOSURE; GENE SILENCING; GENETIC POLYMORPHISM; GENOTOXICITY; HUMAN; HUMAN CELL; LUNG ALVEOLUS EPITHELIUM; MICRONUCLEUS; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DEFICIENCY; PROTEIN FUNCTION; SIGNAL TRANSDUCTION;

ASBESTOS, AMPHIBOLE; ASBESTOS, CROCIDOLITE; CARCINOGENS; CELL LINE; DNA DAMAGE; DNA REPAIR; DNA-BINDING PROTEINS; HUMANS; LUNG; MUTAGENICITY TESTS; MUTAGENS; RESPIRATORY MUCOSA;

EID: 78650280106     PISSN: 00916765     EISSN: 15529924     Source Type: Journal    
DOI: 10.1289/ehp.1002312     Document Type: Article

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