The intracellular quality control system down-regulates the secretion of amyloidogenic apolipoprotein A-I variants: A possible impact on the natural history of the disease

Biochimica et Biophysica Acta - Molecular Basis of Disease

Volumn 1812, Issue 1, 2011, Pages 87-93

  Marchesi, Marta ^a   Parolini, Cinzia ^a   Valetti, Caterina ^b   Mangione, Palma ^c   Obici, Laura ^d   Giorgetti, Sofia ^c   Raimondi, Sara ^c   Donadei, Simona ^d   Gregorini, Gina ^e   Merlini, Giampaolo ^c,d   Stoppini, Monica ^c   Chiesa, Giulia ^a   Bellotti, Vittorio ^c,d  

^a UNIVERSITY OF MILAN   (Italy)

^b UNIVERSITY OF GENOA   (Italy)

^c UNIVERSITY OF PAVIA   (Italy)

^d FONDAZIONE IRCCS POLICLINICO SAN MATTEO   (Italy)

^e Divisione di Nefrologia e Dialisi   (Italy)

Author keywords

Amyloidogenic variants; Apolipoprotein A I; Protein folding; Quality control

Indexed keywords

AMYLOID; APOLIPOPROTEIN A1;

ANIMAL CELL; ANIMAL MODEL; ARTICLE; CELL SECRETION; CYTOPLASM; DOWN REGULATION; ENDOPLASMIC RETICULUM; HETEROZYGOSITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN LOCALIZATION; QUALITY CONTROL;

ADULT; AMINO ACID SUBSTITUTION; AMYLOID; AMYLOIDOSIS, FAMILIAL; ANIMALS; APOLIPOPROTEIN A-I; CERCOPITHECUS AETHIOPS; COS CELLS; ENDOPLASMIC RETICULUM; FEMALE; HETEROZYGOTE; HUMANS; INTRACELLULAR SPACE; MALE; MICROSCOPY, FLUORESCENCE; MUTATION;

EID: 78650269473     PISSN: 09254439     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbadis.2010.07.002     Document Type: Article

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