메뉴 건너뛰기




Volumn 23, Issue 10, 2010, Pages 1173-1180

Motor deficits and neurofibromatosis type 1 (NF1)-associated MRI impairments in a mouse model of NF1

Author keywords

Motor; Mouse model; Neurofibromatosis type 1; Neurofibromin; T2 weighted MRI

Indexed keywords

BASAL GANGLIA; BRAIN REGIONS; COGNITIVE DEFICITS; CORRELATION ANALYSIS; GENETIC DISORDERS; MOTOR DEFICITS; MOTOR PATHWAY; MOTOR PERFORMANCE; MOUSE MODELS; NEUROFIBROMATOSIS TYPE 1; NEUROFIBROMIN; OPTIC TRACT; T2 RELAXATION; T2-WEIGHTED MRI; WHITE MATTER; WILD TYPES;

EID: 78650260684     PISSN: 09523480     EISSN: 10991492     Source Type: Journal    
DOI: 10.1002/nbm.1546     Document Type: Article
Times cited : (7)

References (39)
  • 2
    • 0033659479 scopus 로고    scopus 로고
    • Neurofibromatosis type 1
    • North K. Neurofibromatosis type 1. Am. J. Med. Genet. 2000; 97: 119-127.
    • (2000) Am. J. Med. Genet. , vol.97 , pp. 119-127
    • North, K.1
  • 3
    • 0011146769 scopus 로고    scopus 로고
    • The association of neurofibromatosis type 1 and attention deficit hyperactivity disorder
    • Koth CW, Cutting LE, Denckla MB. The association of neurofibromatosis type 1 and attention deficit hyperactivity disorder. Child Neuropsychol. 2000; 6: 185-194.
    • (2000) Child Neuropsychol. , vol.6 , pp. 185-194
    • Koth, C.W.1    Cutting, L.E.2    Denckla, M.B.3
  • 4
    • 0033605451 scopus 로고    scopus 로고
    • Cognitive impairment in neurofibromatosis type 1
    • Ozonoff S. Cognitive impairment in neurofibromatosis type 1. Am. J. Med. Genet. 1999; 89: 45-52.
    • (1999) Am. J. Med. Genet. , vol.89 , pp. 45-52
    • Ozonoff, S.1
  • 6
    • 0031228268 scopus 로고    scopus 로고
    • Learning disability subtypes in children with neurofibromatosis
    • Brewer VR, Moore BD 3rd, Hiscock M. Learning disability subtypes in children with neurofibromatosis. J. Learn. Disabil. 1997; 30: 521-533.
    • (1997) J. Learn. Disabil. , vol.30 , pp. 521-533
    • Brewer, V.R.1    Moore 3rd, B.D.2    Hiscock, M.3
  • 8
    • 0028307561 scopus 로고
    • Specific learning disability in children with neurofibromatosis type 1: significance of MRI abnormalities
    • North K, Joy P, Yuille D, Cocks N, Mobbs E, Hutchins P, McHugh K, de Silva M. Specific learning disability in children with neurofibromatosis type 1: significance of MRI abnormalities. Neurology. 1994; 44: 878-883.
    • (1994) Neurology. , vol.44 , pp. 878-883
    • North, K.1    Joy, P.2    Yuille, D.3    Cocks, N.4    Mobbs, E.5    Hutchins, P.6    McHugh, K.7    de Silva, M.8
  • 12
    • 0347994921 scopus 로고    scopus 로고
    • Neurofibromatosis type 1: motor and cognitive function and T2-weighted MRI hyperintensities
    • Feldmann R, Denecke J, Grenzebach M, Schuierer G, Weglage J. Neurofibromatosis type 1: motor and cognitive function and T2-weighted MRI hyperintensities. Neurology. 2003; 61: 1725-1728.
    • (2003) Neurology. , vol.61 , pp. 1725-1728
    • Feldmann, R.1    Denecke, J.2    Grenzebach, M.3    Schuierer, G.4    Weglage, J.5
  • 13
    • 11844276586 scopus 로고    scopus 로고
    • T2-weighted hyperintensities (unidentified bright objects) in children with neurofibromatosis 1: their impact on cognitive function
    • Goh WH, Khong PL, Leung CS, Wong VC. T2-weighted hyperintensities (unidentified bright objects) in children with neurofibromatosis 1: their impact on cognitive function. J. Child Neurol. 2004; 19: 853-858.
    • (2004) J. Child Neurol. , vol.19 , pp. 853-858
    • Goh, W.H.1    Khong, P.L.2    Leung, C.S.3    Wong, V.C.4
  • 15
    • 34848884867 scopus 로고    scopus 로고
    • T2 hyperintensities in children with neurofibromatosis type 1 and their relationship to cognitive functioning
    • Hyman SL, Gill DS, Shores EA, Steinberg A, North KN. T2 hyperintensities in children with neurofibromatosis type 1 and their relationship to cognitive functioning. J. Neurol. Neurosurg. Psychiatry. 2007; 78: 1088-1091.
    • (2007) J. Neurol. Neurosurg. Psychiatry. , vol.78 , pp. 1088-1091
    • Hyman, S.L.1    Gill, D.S.2    Shores, E.A.3    Steinberg, A.4    North, K.N.5
  • 17
    • 0029890041 scopus 로고    scopus 로고
    • Neuropsychological significance of areas of high signal intensity on brain MRIs of children with neurofibromatosis
    • Moore BD, Slopis JM, Schomer D, Jackson EF, Levy BM. Neuropsychological significance of areas of high signal intensity on brain MRIs of children with neurofibromatosis. Neurology. 1996; 46: 1660-1668.
    • (1996) Neurology. , vol.46 , pp. 1660-1668
    • Moore, B.D.1    Slopis, J.M.2    Schomer, D.3    Jackson, E.F.4    Levy, B.M.5
  • 19
    • 21744443319 scopus 로고    scopus 로고
    • Neurofibromatosis type 1 - a model for nervous system tumour formation
    • Rubin JB, Gutmann DH. Neurofibromatosis type 1 - a model for nervous system tumour formation? Nat. Rev. Cancer. 2005; 5: 557-564.
    • (2005) Nat. Rev. Cancer. , vol.5 , pp. 557-564
    • Rubin, J.B.1    Gutmann, D.H.2
  • 21
    • 0026521070 scopus 로고
    • Aberrant regulation of ras proteins in malignant tumour cells from type 1 neurofibromatosis patients
    • Basu TN, Gutmann DH, Fletcher JA, Glover TW, Collins FS, Downward J. Aberrant regulation of ras proteins in malignant tumour cells from type 1 neurofibromatosis patients. Nature 1992; 356: 713-715.
    • (1992) Nature , vol.356 , pp. 713-715
    • Basu, T.N.1    Gutmann, D.H.2    Fletcher, J.A.3    Glover, T.W.4    Collins, F.S.5    Downward, J.6
  • 22
    • 0026528368 scopus 로고
    • Abnormal regulation of mammalian p21ras contributes to malignant tumor growth in von Recklinghausen (type 1) neurofibromatosis
    • DeClue JE, Papageorge AG, Fletcher JA, Diehl SR, Ratner N, Vass WC, Lowy DR. Abnormal regulation of mammalian p21ras contributes to malignant tumor growth in von Recklinghausen (type 1) neurofibromatosis. Cell. 1992; 69: 265-273.
    • (1992) Cell. , vol.69 , pp. 265-273
    • DeClue, J.E.1    Papageorge, A.G.2    Fletcher, J.A.3    Diehl, S.R.4    Ratner, N.5    Vass, W.C.6    Lowy, D.R.7
  • 25
    • 0036293742 scopus 로고    scopus 로고
    • Astrocyte-specific inactivation of the neurofibromatosis 1 gene (NF1) is insufficient for astrocytoma formation
    • Bajenaru ML, Zhu Y, Hedrick NM, Donahoe J, Parada LF, Gutmann DH. Astrocyte-specific inactivation of the neurofibromatosis 1 gene (NF1) is insufficient for astrocytoma formation. Mol. Cell. Biol. 2002; 22: 5100-5113.
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 5100-5113
    • Bajenaru, M.L.1    Zhu, Y.2    Hedrick, N.M.3    Donahoe, J.4    Parada, L.F.5    Gutmann, D.H.6
  • 26
    • 0034708076 scopus 로고    scopus 로고
    • A neurofibromatosis-1-regulated pathway is required for learning in Drosophila
    • Guo HF, Tong J, Hannan F, Luo L, Zhong Y. A neurofibromatosis-1-regulated pathway is required for learning in Drosophila. Nature. 2000; 403: 895-898.
    • (2000) Nature. , vol.403 , pp. 895-898
    • Guo, H.F.1    Tong, J.2    Hannan, F.3    Luo, L.4    Zhong, Y.5
  • 30
    • 27644517404 scopus 로고    scopus 로고
    • The HMG-CoA reductase inhibitor lovastatin reverses the learning and attention deficits in a mouse model of neurofibromatosis type 1
    • Li W, Cui Y, Kushner SA, Brown RA, Jentsch JD, Frankland PW, Cannon TD, Silva AJ. The HMG-CoA reductase inhibitor lovastatin reverses the learning and attention deficits in a mouse model of neurofibromatosis type 1. Curr. Biol. 2005; 15: 1961-1967.
    • (2005) Curr. Biol. , vol.15 , pp. 1961-1967
    • Li, W.1    Cui, Y.2    Kushner, S.A.3    Brown, R.A.4    Jentsch, J.D.5    Frankland, P.W.6    Cannon, T.D.7    Silva, A.J.8
  • 33
    • 0004209977 scopus 로고    scopus 로고
    • The Mouse Brain in Stereotaxic Coordinates
    • Academic Press: San Diego,
    • Paxinos G, Franklin KBJ. The Mouse Brain in Stereotaxic Coordinates. Academic Press: San Diego, 2001.
    • (2001)
    • Paxinos, G.1    Franklin, K.B.J.2
  • 34
    • 0033933649 scopus 로고    scopus 로고
    • Voxel-based morphometry--the methods
    • Ashburner J, Friston KJ. Voxel-based morphometry--the methods. Neuroimage. 2000; 11: 805-821.
    • (2000) Neuroimage. , vol.11 , pp. 805-821
    • Ashburner, J.1    Friston, K.J.2
  • 35
    • 0344121207 scopus 로고    scopus 로고
    • Zen and the art of medical image registration: correspondence, homology, and quality
    • Crum WR, Griffin LD, Hill DL, Hawkes DJ. Zen and the art of medical image registration: correspondence, homology, and quality. Neuroimage. 2003; 20: 1425-1437.
    • (2003) Neuroimage. , vol.20 , pp. 1425-1437
    • Crum, W.R.1    Griffin, L.D.2    Hill, D.L.3    Hawkes, D.J.4
  • 38
    • 1242338929 scopus 로고    scopus 로고
    • Voxel-based relaxometry: a new approach for analysis of T2 relaxometry changes in epilepsy
    • Pell GS, Briellmann RS, Waites AB, Abbott DF, Jackson GD. Voxel-based relaxometry: a new approach for analysis of T2 relaxometry changes in epilepsy. Neuroimage. 2004; 21: 707-713.
    • (2004) Neuroimage. , vol.21 , pp. 707-713
    • Pell, G.S.1    Briellmann, R.S.2    Waites, A.B.3    Abbott, D.F.4    Jackson, G.D.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.