Intravasation of bone marrow content. Can its magnitude and effects be modulated by low pressure reaming in a porcine model?

Injury

Volumn 41, Issue SUPPL. 2, 2010, Pages

  Husebye, Elisabeth Ellingsen ^a   Lyberg, Torstein ^b   Opdahl, Helge ^b   Røise, Olav ^a,c  

^a OSLO UNIVERSITY HOSPITAL   (Norway)

^b ULLEVÅL UNIVERSITY HOSPITAL   (Norway)

^c UNIVERSITY OF OSLO   (Norway)

Author keywords

Animal study; Bone marrow embolization; Femoral shaft fracture; Inflammation and coagulation response; Intramedullary pressure; Intramedullary reaming; Porcine model; RIA; Suction irrigation reaming

Indexed keywords

CYTOKINE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD CLOTTING; BLOOD SAMPLING; BONE MARROW DISEASE; BONE MARROW INTRAVASATION; CIRCULATION; CONTROLLED STUDY; CORRELATION ANALYSIS; FEMALE; FEMUR; FIBRINOLYSIS; INTRAMEDULLARY NAILING; INTRAMEDULLARY PRESSURE; LUNG BIOPSY; LUNG EMBOLISM; LUNG PARENCHYMA; MALE; NONHUMAN; POSTOPERATIVE PERIOD; PREOPERATIVE PERIOD; PRESSURE; PRIORITY JOURNAL; SWINE;

ANIMALS; BLOOD COAGULATION; BONE MARROW; CYTOKINES; DISEASE MODELS, ANIMAL; FEMALE; FEMORAL FRACTURES; FIBRINOLYSIS; FRACTURE FIXATION, INTRAMEDULLARY; HEMODYNAMICS; MALE; PRESSURE; PULMONARY EMBOLISM; SWINE;

EID: 78650255817     PISSN: 00201383     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0020-1383(10)70003-6     Document Type: Article

References (42)

1. RJ Baigrie, PM Lamont, D Kwiatkowski Systemic cytokine response after major surgery Br J Surg 79 1992 757 760
2. WL Biffl, EE Moore, FA Moore, VM Peterson Interleukin-6 in the injured patient. Marker of injury or mediator of inflammation? Ann Surg 224 1996 647 664
3. LB Bone, KD Johnson, J Weigelt, R Scheinberg Early versus delayed stabilization of femoral fractures. A prospective randomized study J Bone Joint Surg Am 71 1989 336 340
4. SI Brundage, R McGhan, GJ Jurkovich Timing of femur fracture fixation: effect on outcome in patients with thoracic and head injuries J Trauma 52 2002 299 307
5. NMCW Cheung, KS Leung A study of the pathway of marrow fat intravasation during intramedullary reaming Osteo Trauma Care 12 2004 140 144
6. J Christie, CM Robinson, AC Pell Transcardiac echocardiography during invasive intramedullary procedures J Bone Joint Surg Br 77 1995 450 455
7. J Christie, CM Robinson, B Singer, DC Ray Medullary lavage reduces embolic phenomena and cardiopulmonary changes during cemented hemiarthroplasty J Bone Joint Surg Br 77 1995 456 459
8. E Ellingsen Husebye, T Lyberg, JE Madsen The early effects of intramedullary reaming of the femur on bone mineral density; an experimental study in pigs Scand J Surg 98 2009 189 194
9. AW Elmaraghy, S Aksenov, RJ Byrick Pathophysiological effect of fat embolism in a canine model of pulmonary contusion J Bone Joint Surg Am 81 1999 1155 1164
10. F Gebhard, H Pfetsch, G Steinbach Is interleukin 6 an early marker of injury severity following major trauma in humans? Arch Surg 135 2000 291 295
11. PV Giannoudis, RM Smith, MC Bellamy Stimulation of the inflammatory system by reamed and unreamed nailing of femoral fractures. An analysis of the second hit J Bone Joint Surg Br 81 1999 356 361
12. RJ Goris, JS Gimbrere, JL van Niekerk Early osteosynthesis and prophylactic mechanical ventilation in the multitrauma patient J Trauma 22 1982 895 903
13. PJ Harwood, PV Giannoudis, M van Griensven Alterations in the systemic inflammatory response after early total care and damage control procedures for femoral shaft fracture in severely injured patients J Trauma 58 2005 446 452 discussion: 52-4.
14. EE Husebye, T Lyberg, JE Madsen The influence of a one-step reamer-irrigator-aspirator technique on the intramedullary pressure in the pig femur Injury 37 2006 935 940
15. EE Husebye, T Lyberg, H Opdahl, H Laurvik, O Røise Cardiopulmonary response to reamed intramedullary nailing of the femur comparing traditional reaming with a one-step reamer-irrigator-aspirator reaming system: an experimental study in pigs J Trauma 69 2010 E6 14
16. EE Husebye, T Lyberg, O Roise Bone marrow fat in the circulation: clinical entities and pathophysiological mechanisms Injury 37 Suppl 4 2006 S8 18
17. EE Husebye, H Opdahl, O Røise Coagulation, fibrinolysis, and cytokine responses to intramedullary nailing of the femur. An experimental study in pigs comparing traditional reaming and reaming with a one-step reamer-irrigator-aspirator system Injury 2010 Jul 20
18. D Jacobovitz-Derks, CM Derks Pulmonary neutral fat embolism in dogs Am J Pathol 95 1979 29 42
19. YH Kim, JS Kim, KS Hong Prevalence of fat embolism after total knee arthroplasty performed with or without computer navigation J Bone Joint Surg Am 90 2008 123 128
20. J Krebs, SJ Ferguson, SP Hoerstrup Influence of bone marrow fat embolism on coagulation activation in an ovine model of vertebroplasty J Bone Joint Surg Am 90 2008 349 356
21. E Lin, SE Calvano, SF Lowry Inflammatory cytokines and cell response in surgery Surgery 127 2000 117 126
22. JB Manning, AW Bach, CM Herman, CJ Carrico Fat release after femur nailing in the dog J Trauma 23 1983 322 326
23. KM McIntyre, AA Sasahara The hemodynamic response to pulmonary embolism in patients without prior cardiopulmonary disease Am J Cardiol 28 1971 288 294
24. T Nau, S Aldrian, F Koenig, V Vecsei Fixation of femoral fractures in multiple-injury patients with combined chest and head injuries ANZ J Surg 73 2003 1018 1021
25. JT Nurmi, TL Jarvinen, P Kannus Compaction versus extraction drilling for fixation of the hamstring tendon graft in anterior cruciate ligament reconstruction Am J Sports Med 30 2002 167 173
26. EC Orsini, RJ Byrick, JB Mullen Cardiopulmonary function and pulmonary microemboli during arthroplasty using cemented or non-cemented components. The role of intramedullary pressure J Bone Joint Surg Am 69 1987 822 832
27. A Papathanasopoulos, V Nikolaou, G Petsatodis, PV Giannoudis Multiple trauma: an ongoing evolution of treatment modalities? Injury 40 2009 115 119
28. HC Pape, M van Griensven, FF Hildebrand Systemic inflammatory response after extremity or truncal fracture operations J Trauma 65 2008 1379 1384
29. HC Pape, K Grimme, M van Griensven Impact of intramedullary instrumentation versus damage control for femoral fractures on immunoinflammatory parameters: prospective randomized analysis by the EPOFF Study Group J Trauma 55 2003 7 13
30. HC Pape, G Regel, A Dwenger Influence of thoracic trauma and primary femoral intramedullary nailing on the incidence of ARDS in multiple trauma patients Injury 24 Suppl 3 1993 S82 103
31. HC Pape, RE Schmidt, J Rice Biochemical changes after trauma and skeletal surgery of the lower extremity: quantification of the operative burden Crit Care Med 28 2000 3441 3448
32. EB Riska, H von Bonsdorff, S Hakkinen Prevention of fat embolism by early internal fixation of fractures in patients with multiple injuries Injury 8 1976 110 116
33. CM Robinson, CA Ludlam, DC Ray The coagulative and cardiorespiratory responses to reamed intramedullary nailing of isolated fractures J Bone Joint Surg Br 83 2001 963 973
34. M Schult, R Kuchle, A Hofmann Pathophysiological advantages of rinsing-suction-reaming (RSR) in a pig model for intramedullary nailing J Orthop Res 24 2006 1186 1192
35. HB Soloway, EF Robinson, HK Sleeman Resolution of experimental fat embolism Arch Pathol 90 1970 230 234
36. P Stavlas, PV Giannoudis Bilateral femoral fractures: does intramedullary nailing increase systemic complications and mortality rates? Injury 40 2009 1125 1128
37. VF Tapson Acute pulmonary embolism N Engl J Med 358 2008 1037 1052
38. VF Tapson Acute pulmonary embolism Cardiol Clin 22 2004 353 365 v.
39. C Waydhas, D Nast-Kolb, A Trupka Posttraumatic inflammatory response, secondary operations, and late multiple organ failure J Trauma 40 1996 624 630 discussion: 30-1. (Pubitemid 126425014)
40. K Wenda, G Ritter, J Ahlers, WD von Issendorff [Detection and effects of bone marrow intravasations in operations in the area of the femoral marrow cavity] Unfallchirurg 93 1990 56 61
41. K Wenda, M Runkel, J Degreif, G Ritter Pathogenesis and clinical relevance of bone marrow embolism in medullary nailing - demonstrated by intraoperative echocardiography Injury 24 Suppl 3 1993 S73 S81
42. KE Wood Major pulmonary embolism: review of a pathophysiologic approach to the golden hour of hemodynamically significant pulmonary embolism Chest 121 2002 877 905