Application of the Three Rs to challenge assays used in vaccine testing: Tenth report of the BVAAWF/FRAME/RSPCA/UFAW Joint Working Group on Refinement

Biologicals

Volumn 38, Issue 6, 2010, Pages 684-695

  Jennings, Maggy ^a   Morton, David B ^b   Charton, Emmanuelle ^c   Cooper, Jane ^a   Hendriksen, Coenraad ^d   Martin, Stella ^e   Pearce, Michael C ^f   Price, Scott ^g   Redhead, Keith ^e   Reed, Nick ^h   Simmons, Hugh ^h   Spencer, Stephen ^e   Willingale, Hilary ⁱ  

^a Research Animals Department   (United Kingdom)

^b UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^c European Network of National Information Centers   (France)

^d NETHERLANDS VACCINE INSTITUTE   (Netherlands)

^e Intervet/Schering Plough Animal Health   (United Kingdom)

^f PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United Kingdom)

^g Veterinary Medicines Directorate   (United Kingdom)

^h VETERINARY LABORATORIES AGENCY   (United Kingdom)

ⁱ Home Office Central Research Establishment   (United Kingdom)

Author keywords

Guideline harmonisation; Humane endpoints; Three Rs; Vaccines

Indexed keywords

VACCINE;

ACCLIMATIZATION; ANALGESIA; ANESTHESIA; ANIMAL BEHAVIOR; ANIMAL CARE; ANIMAL HEALTH; ANIMAL HOUSING; ANIMAL HUSBANDRY; ANIMAL TESTING REDUCTION; ANIMAL TESTING REFINEMENT; ANIMAL TESTING REPLACEMENT; BATCH POTENCY TEST; BATCH PROCESS; CONFERENCE PAPER; DATA ANALYSIS; DRUG LEGISLATION; DRUG MANUFACTURE; DRUG POTENCY; DRUG QUALITY; ENVIRONMENTAL ENRICHMENT; EUROPEAN UNION; EXPERIMENTAL ANIMAL WELFARE; GOVERNMENT REGULATION; HEALTH STATUS; OBSERVER BIAS; OBSERVER VARIATION; PERSONNEL MANAGEMENT; PRIORITY JOURNAL; SAMPLE SIZE; SENSITIVITY AND SPECIFICITY; STAFF TRAINING; STATISTICAL ANALYSIS; VALIDATION PROCESS;

ANIMALS; VACCINES; VETERINARY MEDICINE;

ANIMALIA; CLOSTRIDIUM CHAUVOEI; LEPTOSPIRA;

EID: 78650239124     PISSN: 10451056     EISSN: 10958320     Source Type: Journal    
DOI: 10.1016/j.biologicals.2010.04.004     Document Type: Conference Paper

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