Anti-sperm antibody levels are not related to fertilization or pregnancy rates after IVF or IVF/ICSI

Journal of Reproductive Immunology

Volumn 88, Issue 1, 2011, Pages 80-84

  Zini, Armand ^a   Lefebvre, Josee ^c   Kornitzer, Gaelle ^c   Bissonnette, Francois ^b,c   Kadoch, Isaac Jacques ^b,c   Dean, Nicola ^c   Phillips, Simon ^c  

^a MCGILL UNIVERSITY   (Canada)

^b UNIVERSITÉ DE MONTRÉAL   (Canada)

^c OVO Fertility Clinic   (Canada)

Author keywords

Antibodies; Fertilization; Pregnancy; Sperm; Sperm motility

Indexed keywords

IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; SPERM ANTIBODY;

ADULT; ARTICLE; FEMALE; FERTILIZATION IN VITRO; HUMAN; INTRACYTOPLASMIC SPERM INJECTION; MAJOR CLINICAL STUDY; MATERNAL AGE; PREGNANCY RATE; PRIORITY JOURNAL; RETROSPECTIVE STUDY; SEMEN ANALYSIS; SPERMATOZOON MOTILITY;

AUTOANTIBODIES; FEMALE; FERTILIZATION; FERTILIZATION IN VITRO; HUMANS; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; INFERTILITY, MALE; MALE; PREGNANCY; PREGNANCY OUTCOME; PREGNANCY RATE; RETROSPECTIVE STUDIES; SEMEN; SPERM INJECTIONS, INTRACYTOPLASMIC; SPERM MOTILITY; SPERMATOZOA;

EID: 78650234226     PISSN: 01650378     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jri.2010.09.002     Document Type: Article

References (38)

1. Acosta A.A., et al. Fertilization efficiency of morphologically abnormal spermatozoa in assisted reproduction is further impaired by antisperm antibodies on the male partner's sperm. Fertil. Steril. 1994, 62:826-833.
2. Bohring C., Krause W. Characterization of spermatozoa surface antigens by antisperm antibodies and its influence on acrosomal exocytosis. Am. J. Reprod. Immunol. 2003, 50:411-419.
3. Bohring C., Krause W. Immune infertility: towards a better understanding of sperm (auto)-immunity. The value of proteomic analysis. Hum. Reprod. 2003, 18:915-924.
4. Chamley L.W., Clarke G.N. Antisperm antibodies and conception. Semin. Immunopathol. 2007, 29:169-184.
5. Check J.H., et al. Effect of antisperm antibodies on computerized semen analysis. Arch. Androl. 1991, 27:61-63.
6. Check J.H., et al. The effect of sera antisperm antibodies in the female partner on in vivo and in vitro pregnancy and spontaneous abortion rates. Am. J. Reprod. Immunol. 1995, 33:131-133.
7. Check M.L., et al. ICSI as an effective therapy for male factor with antisperm antibodies. Arch. Androl. 2000, 45:125-130.
8. Chiu W.W., Chamley L.W. Clinical associations and mechanisms of action of antisperm antibodies. Fertil. Steril. 2004, 82:529-535.
9. Clarke G.N., et al. Intracytoplasmic sperm injection for treating infertility associated with sperm autoimmunity. Fertil. Steril. 1997, 68:112-117.
10. Collins J.A., et al. Frequency and predictive value of antisperm antibodies among infertile couples. Hum. Reprod. 1993, 8:592-598.
11. Cookson M.S., et al. Can semen analysis predict the presence of antisperm antibodies in patients with primary infertility?. World J. Urol. 1995, 13:318-322.
12. Culligan P.J., et al. Validity and cost-effectiveness of antisperm antibody testing before in vitro fertilization. Fertil. Steril. 1998, 69:894-898.
13. Esteves S.C., et al. Influence of antisperm antibodies in the semen on intracytoplasmic sperm injection outcome. Int. Braz. J. Urol. 2007, 33:795-802.
14. Francavilla F., et al. Failure of intrauterine insemination in male immunological infertility in cases in which all spermatozoa are antibody-coated. Fertil. Steril. 1992, 58:587-592.
15. Francavilla F., et al. Intrauterine insemination with or without mild ovarian stimulation in couples with male subfertility due to oligo/astheno- and/or teratozoospermia or antisperm antibodies: a prospective cross-over trial. Fertil. Steril. 2009, 92:1009-1011.
16. Gubin D.A., et al. Multivariant analysis of men from infertile couples with and without antisperm antibodies. Am. J. Reprod. Immunol. 1998, 39:157-160.
17. Hinting A., et al. Evaluation of the immunological cause of male infertility. Andrologia 1996, 28:123-126.
18. Kortebani G., et al. Leucocyte populations in semen and male accessory gland function: relationship with antisperm antibodies and seminal quality. Andrologia 1992, 24:197-204.
19. Lahteenmaki A., et al. Treatment of severe male immunological infertility by intracytoplasmic sperm injection. Hum. Reprod. 1995, 10:2824-2828.
20. Lahteenmaki A., et al. Intra-uterine insemination versus cyclic, low-dose prednisolone in couples with male antisperm antibodies. Hum. Reprod. 1995, 10:142-147.
21. Leushuis E., et al. Immunoglobulin g antisperm antibodies and prediction of spontaneous pregnancy. Fertil. Steril. 2009, 92:1659-1665.
22. Lombardo F., et al. Antisperm immunity in natural and assisted reproduction. Hum. Reprod. Update 2001, 7:450-456.
23. Maier D.B., Parke A. Subclinical autoimmunity in recurrent aborters. Fertil. Steril. 1989, 51:280-285.
24. Mazumdar S., Levine A.S. Antisperm antibodies: etiology, pathogenesis, diagnosis, and treatment. Fertil. Steril. 1998, 70:799-810.
25. Mercan R., et al. Impact of fertilization history and semen parameters on ICSI outcome. J. Assist. Reprod. Genet. 1998, 15:39-45.
26. Munuce M.J., et al. Relationship between antisperm antibodies, sperm movement, and semen quality. Urol. Int. 2000, 65:200-203.
27. Nagy Z.P., et al. Results of 55 intracytoplasmic sperm injection cycles in the treatment of male-immunological infertility. Hum. Reprod. 1995, 10:1775-1780.
28. Ombelet W., et al. Treatment of male infertility due to sperm surface antibodies: IUI or IVF?. Hum. Reprod. 1997, 12:1165-1170.
29. Putowski L., et al. The immunological profile of infertile women after repeated IVF failure (preliminary study). Eur. J. Obstet. Gynecol. Reprod. Biol. 2004, 112:192-196.
30. Rajah S.V., et al. The effects on in-vitro fertilization of autoantibodies to spermatozoa in subfertile men. Hum. Reprod. 1993, 8:1079-1082.
31. Scott L., et al. The morphology of human pronuclear embryos is positively related to blastocyst development and implantation. Hum. Reprod. 2000, 15:2394-2403.
32. Simpson J.L., et al. Prospective study showing that antisperm antibodies are not associated with pregnancy losses. Fertil. Steril. 1996, 66:36-42.
33. Sinisi A.A., et al. Prevalence of antisperm antibodies by spermMARtest in subjects undergoing a routine sperm analysis for infertility. Int. J. Androl. 1993, 16:311-314.
34. Sukcharoen N., Keith J. The effect of the antisperm auto-antibody-bound sperm on in vitro fertilization outcome. Andrologia 1995, 27:281-289.
35. Van Blerkom J., Henry G. Oocyte dysmorphism and aneuploidy in meiotically mature human oocytes after ovarian stimulation. Hum. Reprod. 1992, 7:379-390.
36. Van Weert J.M., et al. A prediction model for ongoing pregnancy after in vitro fertilization in couples with male subfertility. J. Reprod. Med. 2008, 53:250-256.
37. Vujisic S., et al. Antisperm antibodies in semen, sera and follicular fluids of infertile patients: relation to reproductive outcome after in vitro fertilization. Am. J. Reprod. Immunol. 2005, 54:13-20.
38. World Health Organization WHO Laboratory Manual for the Examination of Human Semen and Sperm-Cervical Mucus Interaction 1999, Cambridge University Press, Cambridge.