Antisperm immunity in natural and assisted reproduction

Human Reproduction Update

Volumn 7, Issue 5, 2001, Pages 450-456

  Lombardo, F ^a   Gandini, L ^a   Dondero, F ^a   Lenzi, A ^a  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

Antisperm antibodies; Intracytoplasmic sperm injection; Intrauterine insemination; IVF

Indexed keywords

AUTOANTIBODY; CORTICOSTEROID; DEXAMETHASONE; IMMUNOGLOBULIN A; IMMUNOGLOBULIN ANTIBODY; IMMUNOGLOBULIN CLASS; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; IMMUNOSUPPRESSIVE AGENT; METHYLPREDNISOLONE; SPERM ANTIBODY; SPERM ANTIGEN; TESTOSTERONE;

ANTIBODY DETECTION; ANTIGEN ANTIBODY REACTION; ARTICLE; ARTIFICIAL INSEMINATION; CONTROLLED STUDY; DISEASE SEVERITY; FEMALE; FERTILIZATION IN VITRO; GAMETE; HUMAN; HUMAN CELL; IMMUNITY; IMMUNOPATHOGENESIS; IMMUNOPATHOLOGY; INTRACYTOPLASMIC SPERM INJECTION; INTRAUTERINE INSEMINATION; MAJOR CLINICAL STUDY; MALE; MALE FERTILITY; MALE GENITAL SYSTEM; MALE INFERTILITY; MEDICAL ASSESSMENT; MEDICAL CARE; MEDICAL RESEARCH; PRIORITY JOURNAL; REPRODUCTION; SEMEN ANALYSIS; SPERMATOZOON; SPERMATOZOON MOTILITY; SPERMATOZOON PENETRATION; TREATMENT OUTCOME; UTERINE CERVIX MUCUS;

ANIMALS; ANTIBODIES; AUTOIMMUNITY; FERTILIZATION; HUMANS; INFERTILITY, MALE; MALE; SPERMATOZOA;

EID: 0034856477     PISSN: 13554786     EISSN: None     Source Type: Journal    
DOI: 10.1093/humupd/7.5.450     Document Type: Article

References (72)

1. Fertilisation efficiency of morphologically abnormal spermatozoa in assisted reproduction is further impaired by antisperm antibodies on the male partner's sperm
2. Antibodies to human spermatozoa impede sperm penetration of cervical mucus or hamster eggs
3. The poor prognostic value of low to moderate levels of sperm surface-bound antibodies
4. Sperm specific isoantibodies and autoantibodies inhibit the binding of human sperm to the human zona pellucida
5. Relationship of sperm antibodies in women and men to human in vitro fertilisation, cleavage, and pregnancy rate
6. Induction of the shaking phenomenon by IgA class antispermatozoal from serum
7. Immunoglobulin class and regional specificity of antispermatozoal autoantibodies blocking cervical mucus penetration by human spermatozoa
8. Sperm antibodies and human fertilisation
9. Sperm antibodies, immunoglobulins, and complement in human follicular fluid
10. Sperm antibodies and human fertilisation
11. Intracytoplasmic sperm injection for treating infertility associated with sperm autoimmunity
12. Corticosteroid therapy for male autoimmune infertility
13. In-vitro processing of sperm with autoantibodies and in-vitro fertilisation results
14. Treatment and follow-up of patients with infertility due to spermagglutinins
15. A comparison of the direct immunobead test and other tests for antisperm antibodies detection
16. Male immunological infertility in assisted reproduction
17. The indirect immunobead test for seminal antisperm antibodies and fertilisation rates at in-vitro fertilisation
18. Interference of antisperm antibodies with the induction of the acrosome reaction by zona pellucida (ZP) and its relationship with the inhibition of ZP binding
19. Naturally occurring antisperm antibodies in men: Interference with fertility and implications for treatment
20. Effects of incubation time in serum and capacitation on spermatozoal reactivity with antisperm antibodies
21. Study of antisperm antibodies bound to the sperm cell surface and their relationship to circulating ASA
22. Immature germ cell separation using a modified discontinuous Percoll gradient technique in human semen
23. What functions of the sperm cell are measured by in vitro fertilisation of zona-free hamster eggs?
24. The effect of immunoglobulin occurring on human sperm in vivo on the human sperm/hamster ova penetration assay
25. Steroid treatment of male subfertility caused by antisperm antibodies
26. Cyclic prednisolone therapy for male infertility associated with autoantibodies to spermatozoa
27. Molecular events leading to fertilisation - A review
28. Immunoglobulin class of antispermatozoal antibodies from infertile men and inhibition of in vitro sperm penetration into cervical mucus
29. The significance of the Fc part of ASA for the shaking phenomenon in the sperm-cervical mucus contact test
30. The fertilisation of human oocytes by spermatozoa from men with antispermatozoal antibodies in semen
31. Antisperm antibodies associated with infertility: Properties and encoding genes of target antigens
32. The 'unexplained' poor postcoital test
33. Human sperm penetration assay as an indication of sperm function in human in vitro fertilisation
34. In-vitro fertilisation in the presence of antisperm antibodies detected by the mixed antiglobulin reaction (MAR) and the tray agglutination test (TAT)
35. Treatment of severe male immunological infertility by intracytoplasmic sperm injection
36. Immunological usefulness of semen manipulation for artificial insemination homologous (AIH) in subjects with antisperm antibodies bound to sperm surface
37. Preliminary data on sperm-mucus interaction and sperm-bound antibodies regarding percent positivity, Ig class and site of the reaction
38. In vitro sperm capacitation to treat antisperm antibodies bound to the sperm surface
39. A sperm-zona pellucida binding test and in vitro fertilisation
40. Does intraperitoneal insemination in absence of prior sensitization carry with it a risk of subsequent immunity to sperm?
41. Can computer analysed sperm motility be normal in seminal samples with high percentage of antisperm antibody bound to sperm surface?
42. Presence and distribution of antisperm antibody reacting antigens in: 1) immature germ cells and sperm populations and 2) microaspirated spermatozoa
43. Macrophages and infertility: Enhancement of human macrophage-mediated sperm killing by antisperm antibodies
44. Inhibition of human sperm-zona pellucida tight binding in the presence of antisperm antibody positive polyclonal patient sera
45. Relationship of antisperm antibodies to oocyte fertilisation in in-vitro fertilisation-embryo transfer
46. Role of guinea-pig sperm autoantigens in capacitation and the acrosome reaction
47. Sperm motility on postcoital testing correlates with male autoimmunity to sperm
48. Effects of antisperm antibodies in seminal plasma upon sperm function
49. Evaluation of the male factor in relation to in vitro fertilisation
50. Changes in sperm antibody test results when spermatozoa are subjected to capacitating conditions
51. Role of guinea-pig autoantigens in sperm binding to the zona pellucida and oocyte penetration
52. Localised surface antigens of guinea pig sperm migrate to new regions prior to fertilisation
53. Results of 55 intracytoplasmic sperm injection cycles in the treatment of male-immunological infertility
54. Monoclonal antibodies to rabbit sperm autoantigens. I. Inhibition of in vitro fertilisation and localisation on the egg
55. The clinical relevance of classes of immunoglobulins on spermatozoa from infertile and vasovasostomized males
56. Testicular origin of immunobead reacting antigens in human sperm
57. Lack of immunisation after intraperitoneal insemination (IPI) of spermatozoa
58. The effects on in-vitro fertilisation of autoantibodies to spermatozoa in subfertile men
59. Autoantibodies against spermatozoa in sterile men
60. Mouse sperm antigens that participate in fertilisation. II. Inhibition of sperm penetration through the zona pellucida using monoclonal antibodies
61. Immunoglobulins from human follicular fluid induce the acrosome reaction in human sperm
62. Effects of sperm immobilising antibodies on sperm-zona pellucida tight binding
63. Methylprednisolone treatment of immunologic infertility in the male
64. Therapy of immunological infertility
65. Immunological factors in infertility
66. Inhibition of fertilisation of rabbit ova in vitro by antibody to the inner acrosomal membrane of rabbit spermatozoa
67. The effect of the antisperm auto-antibody-bound sperm on in vitro fertilisation outcome
68. Inhibition of sperm penetration through human zona pellucida by antisperm antibodies
69. Male immunologic infertility: Sperm performance on in vitro fertilisation
70. Interaction between human cervical and sperm surface antibodies
71. Impact of immunoglobulin isotype and sperm surface location of antisperm antibodies on fertilisation in vitro in the human
72. The predictive value of the zona-free hamster egg penetration test in relation to in-vitro fertilisation at various insemination concentrations