Anti red scorpion venom activity of Andrographis paniculata

Asian Journal of Pharmaceutical and Clinical Research

Volumn 3, Issue 4, 2010, Pages 76-79

  Brahmane, Ranjana I ^a   Pathak, Swanand S ^a   Wanmali, Vikrant V ^a   Salwe, Kartik J ^a   Premendran, S John ^b   Shinde, Bhawna B ^a  

^a MAHATMA GANDHI INSTITUTE OF MEDICAL SCIENCES   (India)

^b Mamta Medical College   (India)

Author keywords

Adrographis Paniculata; LD99; Mesobuthus tamulus

Indexed keywords

ALCOHOL; ANDROGRAPHIS PANICULATA EXTRACT; SCORPION VENOM;

ACUTE TOXICITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG DOSE COMPARISON; DRUG MECHANISM; ENVENOMATION; IN VITRO STUDY; IN VIVO STUDY; LETHAL DOSE; MESOBUTHUS TAMULUS; MOUSE; NONHUMAN; POISONOUS SCORPION; SURVIVAL TIME; SWISS WEBSTER MOUSE;

EID: 78650219729     PISSN: 09742441     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (16)

1. Ismail M. The scorpion envenoming syndrome. Toxicon1995;33: 825-58. PMID: 8588209
2. Vasconcelos F, Lanchote VL, Bendhack LM, Giglio JR, Sampaio SV, Arantes EC. Effects of voltage-gated Na+ channel toxins from Tityus serrulatus venom on rat arterial blood pressure and plasma catecholamines. Comp Biochem Physiol C Toxicol Pharmacol 2005;141: 85-92. DOI: 10.1016/j.cca.2005.05.012
3. Bawaskar HS. Diagnostic cardiac premonitory signs and symptoms of red scorpion sting. Lancet 1982;1: 552-4. PMID: 6120403
4. Bawaskar HS, Bawaskar PH. Cardiovascular manifestations of severe scorpion sting in India (review of 34 children). Ann Trop Paediatr 1991;11: 381-7. PMID: 172179
5. Freire-Maia L, Pinto GI, Franco I. Mechanism of the cardiovascular effects produced by purified scorpion toxin in rat. J Pharmacol Exp Ther 1974;188: 207-13. PMID: 4809270
6. Mundle PM. Scorpion sting. Br Med J 1961;1: 1042. doi: 10.1136/bmj.1.5231.1042-a
7. Bawaskar HS. Management of severe scorpion sting at rural settings: what is the role of scorpion antivenom? J Venom Anim Toxins incl Trop Dis [serial on the Internet]. 2005 Mar [cited 2010 Apr 06]; 11(1): 3-7.
8. Bawaskar HS, Bawaskar PH. Severe scorpion envenoming by Indian red scorpion Mesobuthus tamulus: the use of prazosin therapy. Q J Med1996; 89: 701-4. doi: 10.1093/qjmed/89.9.701
9. Bawaskar HS. Snake venoms and antivenoms: critical supply issues. J Assoc Physicians India 2004;52: 11-3. PMID: 15633710
10. Otten EJ. Venomous animal injuries. In, Rosen P, Barkin R (ed). Emergency medicine concepts and clinical practices. New York: Mosby, 1998; 924-940.
11. Chang HM. Pharmacology and applications of Chinese materia medica.Vol.1. Singapore: World Scientific, 1986;918-928.
12. Nazimuddin et al. Effect of Andrographis paniculata on snake venom-induced death and its mechanism. Indian J. of Pharmaceutical Sci. 1978;40: 132- 4.
13. Mahanta M, Mukharjee AK. Neutralization of lethality, myotoxicty and toxic enzymes of Naja kaouthia venom by Mimosa pudica root extracts. J Ethnopharmacol 2001;75: 55- 60. PMID: 11282444
14. Turner RA. Screening methods in Pharmacology. New York: Academic Press, 1965.
15. Alam MI, Gomes A. Snake venom neutralization by Indian Medicinal Plants Vitex negundo and Emblica officinalis root extracts. J Ethnopharmacol 2003;86: 75-80. PMID: 12686445
16. Pound P, Ebrahim S, Sandercock P, Bracken MB, Roberts I. Where is the evidence that animal research benefits humans? BMJ 2004;328: 514-7. PMID: 14988196