Analysis of the polymorphisms in non-homologous DNA end joining (NHEJ) gene Ku70 and Ligase IV in sporadic breast cancer in women

Polish Journal of Pathology

Volumn 61, Issue 1, 2010, Pages 27-31

  Sobczuk, Anna ^a   Smolarz, Beata ^a   Romanowicz, Hanna ^a   Zadrozny, Marek ^a   Baszczyński, Jakub ^a   Westfal, Bogusław ^a   Pertyński, Tomasz ^a  

^a POLISH MOTHER S MEMORIAL HOSPITAL RESEARCH INSTITUTE   (Poland)

Author keywords

Breast cancer; Gene polymorphism; Ku70; Ligase IV; NHEJ

Indexed keywords

DNA; LIGASE;

BREAST TUMOR; DNA REPAIR; DOUBLE STRANDED DNA BREAK; FEMALE; GENETIC POLYMORPHISM; GENETICS; HUMAN;

BREAST NEOPLASMS; DNA; DNA BREAKS, DOUBLE-STRANDED; DNA REPAIR; FEMALE; HUMANS; LIGASES; POLYMORPHISM, GENETIC;

EID: 78650219236     PISSN: 12339687     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (15)

1. Davidson JM, Gorringe KL, Chin SF, et al. Molecular cytogenetic analysis of breast cancer cell lines. Br J Cancer 2000; 83: 1309-1317.
2. Forozan F, Mahlamaki EH, Monni O, et al. Comparative genomic hybridization analysis of 38 breast cancer cell lines: a basis for interpreting complementary DNA microarray data. Cancer Res 2000; 60: 4519-4525.
3. Kytola S, Rummukainen J, Nordgren A, et al. Chromosomal alterations in 15 breast cancer cell lines by comparative genomic hybridization and spectral karyotyping. Genes Chromosomes Cancer 2000; 28: 308-317.
4. Loveday RL, Greenman J, Simcox DL, et al. Genetic changes in breast cancer detected by comparative genomic hybridisation. Int J Cancer 2000; 86: 494-500.
5. Bahar R, Hartmann CH, Rodriguez KA, et al. Increased cell- to-cell variation in gene expression in ageing mouse heart. Nature 2006; 441: 1011-1014.
6. Vijg J, Dolle MET. Large genome rearrangements as a primary cause of aging. Mech. Ageing Dev 2002; 123: 907-915.
7. Jackson SP. Sensing and repairing DNA double-strand breaks. Carcinogenesis. 2002; 23: 687-696.
8. Helleday T. Pathways for mitotic homologous recombination in mammalian cells. Mutat. Res. 2003; 532: 103-115.
9. Lieber MR, Ma Y, Pannicke U, et al. Nat Rev Mol Cell Biol 2003; 4: 712-720.
10. Seluanov A, Mittelman D, Pereira-Smith OM, et al. DNA end joining becomes less efficient and more error-prone during cellular senescence. Proc. Natl Acad. Sci. USA. 2004; 101: 7624-7629.
11. Kirk BW, Feinsod M, Favis R, et al. Single nucleotide polymorphism seeking long term association with complex disease. Nucleic Acids Res 2002; 30: 3295-3311.
12. Kuschel B, Auranen A, McBride S, et al. Variants in DNA double-strand break repair genes and breast cancer susceptibility. Hum Mol Genet 2002; 11: 1399-1407.
13. Willems P, Claes K, Baeyens A, et al. Polymorphisms in nonhomologous end-joining genes associated with breast cancer risk and chromosomal radiosensitivity. Genes Chromosomes Cancer 2008; 47: 137-148.
14. Fu YP, Yu JC, Cheng TC, et al. Breast cancer risk associated with genotypic polymorphism of the nonhomologous end- joining genes: a multigenic study on cancer susceptibility. Cancer Res. 2003; 63: 2440-2446.
15. Han J, Haiman C, Niu T, et al. Genetic variation in DNA repair pathway genes and premenopausal breast cancer risk. Breast Cancer Res Treat 2009; 115: 613-622.