Intrapulmonary inflammatory response in critically ill patients with pneumonia;Respuesta inflamatoria a nivel intrapulmonar en enfermos críticos con neumonía

Medicina Intensiva

Volumn 34, Issue 9, 2010, Pages 590-594

  Estella, A ^a  

^a HOSPITAL DE JEREZ   (Spain)

Author keywords

Bronchoalveolar lavage; Cytokines; Mechanical ventilation; Pneumonia

Indexed keywords

CYTOKINE; GRANULOCYTE COLONY STIMULATING FACTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 6; INTERLEUKIN 8; ISOTONIC SOLUTION; SODIUM CHLORIDE; TUMOR NECROSIS FACTOR ALPHA;

AGE; ANTIBIOTIC THERAPY; APACHE; ARTICLE; ARTIFICIAL VENTILATION; BACTERIUM CULTURE; CRITICALLY ILL PATIENT; HUMAN; IMMUNE RESPONSE; INFLAMMATION; INTENSIVE CARE UNIT; LENGTH OF STAY; LUNG LAVAGE; MORTALITY; OBSERVATIONAL STUDY; PNEUMONIA; PROSPECTIVE STUDY; PROTEIN EXPRESSION;

BRONCHOALVEOLAR LAVAGE FLUID; CRITICAL ILLNESS; CYTOKINES; HUMANS; MIDDLE AGED; PNEUMONIA; PROSPECTIVE STUDIES;

EID: 78650214101     PISSN: 02105691     EISSN: 15786749     Source Type: Journal    
DOI: 10.1016/j.medin.2010.05.008     Document Type: Article

References (26)

1. Olaechea P. Infecciones bacterianas en el paciente crítico: revisión de los estudios publicados entre 2006 y 2008. Med Intensiva 2009, 33:196-206.
2. Fagon J.Y., Chastre J., Wolff M., Gervais C., Parer-Aubas S., Stephan F., et al. Invasive and noninvasive strategies for management of suspected ventilator-associated pneumonia. A randomized trial. Ann Intern Med 2000, 132:621-630.
3. A randomized trial of diagnostic techniques for ventilator associated pneumonia. N Engl J Med 2006, 355:2619-2630. The Canadian Critical Care Trial Group.
4. Fàbregas N., Torres A., El-Ebiary M., Ramírez J., Hernández C., González J., et al. Histopathologic and microbiologic aspects of ventilator associated pneumonia. Anesthesiology 1996, 84:760-771.
5. Charo I.F., Ransohoff M. The many roles of chemokines and chemokine receptors in inflammation. N Engl J Med 2006, 354:610-621.
6. Stuber F., Wrigge H., Schroeder S., Wetegrove S., Zinserling J., Hoeft A., et al. Kinetic and reversibility of mechanical ventilation-associated pulmonary and systemic inflammatory response in patients with acute lung injury. Intensive Care Med 2002, 28:834-841.
7. Ranieri V.M., Suter P.M., Tortorella C., De Tullio R., Dayer J.M., Brienza A., et al. Effect of mechanical ventilation on inflammatory mediators in patients with acute respiratory distress syndrome: a randomized controlled trial. JAMA 1999, 282:54-61.
8. Millo J.L., Schultz M.J., Williams C., Weverling G.J., Ringrose T., Mackinlay C.I., et al. Compartmentalisation of cytokines and cytokine inhibitors in ventilator-associated pneumonia. Intensive Care Med 2004, 30:68-74.
9. Dehoux M.S., Boutten A., Ostinelli J., Seta M. Compartmentalized cytokine production within the human lung in unilateral pneumonia. Am J Respir Crit Care Med 1994, 150:710-716.
10. Monton C., Torres A. Lung inflammatory response in pneumonia. Monaldi Arch Chest Dis 1998, 53:56-63.
11. Schutte H., Lohmeyer J., Rosseau S., Ziegler S., Siebert C., Kielisch H., et al. Bronchoalveolar and systemic cytokine profiles in patients with ARDS, severe pneumonia and cardiogenic pulmonary oedema. Eur Respir J 1996, 9:1858-1867.
12. Puneet P., Moochhala S., Bhatia M. Chemokines in acute respiratory distress syndrome. Am J Physiol Lung Cell Mol Physiol 2005, 288:3-15.
13. Wu C.L., Lee Y.L., Chang K.M., Chang G.C., King S.L., Chiang C.D., et al. Bronchoalveolar interleukin-1 beta: a marker of bacterial burden in mechanicallyventilated patients with community-acquired pneumonia. Crit Care Med 2003, 31:812-817.
14. Monton C., Torres A., El-Ebiary M., Filella X., Xaubet A., Puig de la Bellacsa J. Cytokine expression in severe pneumonia: a bronchoalveolar lavage study. Crit Care Med 1999, 27:1745-1753.
15. Aggarwal A., Baker C.S., Evans T.W., Haslam P.L. G-CSF and IL-8 but not GM-CSF correlate with severity of pulmonary neutrophilia in acute respiratory distress syndrome. Eur Respir J 2000, 15:895-901.
16. Nelson S., Mason C.M., Kolls J., Summer W.R. Pathophysiology of pneumonia. Clin Chest Med 1995, 1:1-12.
17. Nelson S., Noel P., Bokulic R., Bagby G., Summer W.R. Murine recombinant tumor necrosis factor enhances pulmonary host defense against Staphylococcus aureus. Am Rev Respir Dis 1989, 139:A357.
18. Maus U., Rosseau S., Knies U., Seeger W., Lohmeyer J. Expression of pro-inflammatory cytokines by flow-sorted macrophages in severe pneumonia. Eur Respir J 1998, 11:534-541.
19. Puren A.J., Feldman C., Savage N., Becker P.J., Smith C. Patterns of cytokine expression in community-acquired pneumonia. Chest 1995, 107:1342-1349.
20. Laichalk L.L., Kunkel S.L., Strieter R.M., Danforth J.M., Bailie M.B., Standiford T.J. Tumor necrosis factor mediates lung antibacterial host defense in murine Klebsiella pneumonia. Infect Immun 1996, 64:5211-5218.
21. Brieland J.K., Remick D.G., Freeman P.T., Hurley M.C., Fantone J.C., Engleberg N.C. In vivo regulation of replicative Legionella pneumophila lung infection by endogenous tumor necrosis factor alpha and nitric oxide. Infect Immun 1995, 63:3253-3258.
22. Mehrad B., Strieter R.M., Standiford T.J. Role of TNF-alpha in pulmonary host defense in murine invasive aspergillosis. J Immunol 1999, 162:1633-1640.
23. Summah H., Qu Jie-Ming A. Biomarkers: A definite plus in pneumonia. Mediators Inflamm 2009, 2009:675753.
24. Pierrakos C, Vincent JL Sepsis biomarkers: A review. Crit Care 2010, 14:R15.
25. Cheng K., Zhang H., Lin C.Y., Slutsky A.S. Ventilation with negative airway pressure induces a cytokine response in isolated mouse lung. Anesth Analg 2002, 94:1577-1582.
26. Wilson MR, Choudhury S, Takata M Pulmonary inflammation induced by high-stretch ventilation is mediated by tumor necrosis factor signaling in mice. Am J Physiol Lung Cell Mol Physiol 2005, 288:599-607.