메뉴 건너뛰기




Volumn 71, Issue 1, 2011, Pages 113-115

Premature senescence induced by DNA demethylating agent (Decitabine) as therapeutic option for malignant pleural mesothelioma

Author keywords

Decitabine; DNA demethylation; Drug induced premature senescence; Malignant pleural mesothelioma

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; ATM PROTEIN; ATR PROTEIN; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 45; HISTONE H2AX; PROTEIN P16; PROTEIN P21; PROTEIN P27;

EID: 78650201751     PISSN: 01695002     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lungcan.2010.10.016     Document Type: Letter
Times cited : (26)

References (11)
  • 1
    • 56649103705 scopus 로고    scopus 로고
    • Pathogenesis of malignant pleural mesothelioma and the role of environmental and genetic factors
    • Weiner S.J., Neragi-Miandoab S. Pathogenesis of malignant pleural mesothelioma and the role of environmental and genetic factors. Cancer Res Clin Oncol 2009, 135:15-27.
    • (2009) Cancer Res Clin Oncol , vol.135 , pp. 15-27
    • Weiner, S.J.1    Neragi-Miandoab, S.2
  • 2
    • 70350345499 scopus 로고    scopus 로고
    • Decitabine, differently from DNMT1 silencing, exerts its antiproliferative activity through p21 upregulation in malignant pleural mesothelioma (MPM) cells
    • Amatori S., Papalini F., Lazzarini R., Donati B., Bagaloni I., Rippo M.R., et al. Decitabine, differently from DNMT1 silencing, exerts its antiproliferative activity through p21 upregulation in malignant pleural mesothelioma (MPM) cells. Lung Cancer 2009, 66:184-190.
    • (2009) Lung Cancer , vol.66 , pp. 184-190
    • Amatori, S.1    Papalini, F.2    Lazzarini, R.3    Donati, B.4    Bagaloni, I.5    Rippo, M.R.6
  • 3
    • 34447543913 scopus 로고    scopus 로고
    • Cellular senescence in cancer and aging
    • Collado M., Blasco M.A., Serrano M. Cellular senescence in cancer and aging. Cell 2007, 130:223-233.
    • (2007) Cell , vol.130 , pp. 223-233
    • Collado, M.1    Blasco, M.A.2    Serrano, M.3
  • 4
    • 33750326078 scopus 로고    scopus 로고
    • Phase I study of Decitabine-mediated gene expression in patients with cancers involving the lungs, esophagus, or pleura
    • Schrump D.S., Fischette M.R., Nguyen D.M., Zhao M., Li X., Kunst T.F., et al. Phase I study of Decitabine-mediated gene expression in patients with cancers involving the lungs, esophagus, or pleura. Clin Cancer Res 2006, 12:5777-5785.
    • (2006) Clin Cancer Res , vol.12 , pp. 5777-5785
    • Schrump, D.S.1    Fischette, M.R.2    Nguyen, D.M.3    Zhao, M.4    Li, X.5    Kunst, T.F.6
  • 5
    • 0035374458 scopus 로고    scopus 로고
    • DNA methyltransferase inhibition in normal human fibroblasts induces a p21-dependent cell cycle withdrawal
    • Young J.I., Smith J.R. DNA methyltransferase inhibition in normal human fibroblasts induces a p21-dependent cell cycle withdrawal. J Biol Chem 2001, 276(22):19610-19616.
    • (2001) J Biol Chem , vol.276 , Issue.22 , pp. 19610-19616
    • Young, J.I.1    Smith, J.R.2
  • 6
    • 78650201378 scopus 로고    scopus 로고
    • DNA demethylating antineoplastic strategies: a comparative point of view
    • Amatori S., Bagaloni I., Donati B., Fanelli M. DNA demethylating antineoplastic strategies: a comparative point of view. Genes Cancer 2010, 1(3):197-209.
    • (2010) Genes Cancer , vol.1 , Issue.3 , pp. 197-209
    • Amatori, S.1    Bagaloni, I.2    Donati, B.3    Fanelli, M.4
  • 7
    • 77954661284 scopus 로고    scopus 로고
    • Malten, a new synthetic molecule showing in vitro antiproliferative activity against tumor cells and induction of complex DNA structural alterations
    • Amatori S., Bagaloni I., Macedi E., Formica M., Giorgi L., Fusi V., et al. Malten, a new synthetic molecule showing in vitro antiproliferative activity against tumor cells and induction of complex DNA structural alterations. Br J Cancer 2010, 103:239-248.
    • (2010) Br J Cancer , vol.103 , pp. 239-248
    • Amatori, S.1    Bagaloni, I.2    Macedi, E.3    Formica, M.4    Giorgi, L.5    Fusi, V.6
  • 8
    • 52949152429 scopus 로고    scopus 로고
    • Accelerated senescence: an emerging role in tumor cell response to chemotherapy and radiation
    • Gewirtz D.A., Holt S.E., Elmore L.W. Accelerated senescence: an emerging role in tumor cell response to chemotherapy and radiation. Biochem Pharmacol 2008, 76:947-957.
    • (2008) Biochem Pharmacol , vol.76 , pp. 947-957
    • Gewirtz, D.A.1    Holt, S.E.2    Elmore, L.W.3
  • 9
    • 33749023927 scopus 로고    scopus 로고
    • Gadd45a suppresses Ras-driven mammary tumorigenesis by activation of c-Jun NH2-terminal kinase and p38 stress signaling resulting in apoptosis and senescence
    • Tront J.S., Hoffman B., Liebermann D.A. Gadd45a suppresses Ras-driven mammary tumorigenesis by activation of c-Jun NH2-terminal kinase and p38 stress signaling resulting in apoptosis and senescence. Cancer Res 2006, 66:8448-8454.
    • (2006) Cancer Res , vol.66 , pp. 8448-8454
    • Tront, J.S.1    Hoffman, B.2    Liebermann, D.A.3
  • 10
    • 0037667702 scopus 로고    scopus 로고
    • Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence
    • Narita M., Nunez S., Heard E., Narita M., Lin A.W., Hearn S.A., et al. Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence. Cell 2003, 113:703-713.
    • (2003) Cell , vol.113 , pp. 703-713
    • Narita, M.1    Nunez, S.2    Heard, E.3    Narita, M.4    Lin, A.W.5    Hearn, S.A.6
  • 11
    • 65349131915 scopus 로고    scopus 로고
    • ATM-ATR-dependent up-regulation of DNAM-1 and NKG2D ligands on multiple myeloma cells by therapeutic agents results in enhanced NK-cell susceptibility and is associated with a senescent phenotype
    • Soriani A., Zingoni A., Cerboni C., Iannitto M.L., Ricciardi M.R., Di Gialleonardo V., et al. ATM-ATR-dependent up-regulation of DNAM-1 and NKG2D ligands on multiple myeloma cells by therapeutic agents results in enhanced NK-cell susceptibility and is associated with a senescent phenotype. Blood 2009, 113(15):3503-3511.
    • (2009) Blood , vol.113 , Issue.15 , pp. 3503-3511
    • Soriani, A.1    Zingoni, A.2    Cerboni, C.3    Iannitto, M.L.4    Ricciardi, M.R.5    Di Gialleonardo, V.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.