Three-dimensional QSAR and pharmacophore mapping of biphenyl benzoic acid derivatives as selective human β3-adrenergic receptor agonists

Medicinal Chemistry Research

Volumn 19, Issue 9, 2010, Pages 1174-1190

  Telvekar, Vikas N ^a   Patel, Dharmeshkumar J ^a   Jadhav, Nikhil C ^a   Mishra, Sanket J ^a  

^a INSTITUTE OF CHEMICAL TECHNOLOGY   (India)

Author keywords

3 Adrenergic receptor; 3D QSAR; CoMFA; Common pharmacophore hypothesis; CoMSIA; PHASE

Indexed keywords

BENZOIC ACID DERIVATIVE; BETA 3 ADRENERGIC RECEPTOR; BETA 3 ADRENERGIC RECEPTOR STIMULATING AGENT; BIPHENYL DERIVATIVE;

ARTICLE; COMMON PHARMACOPHORE HYPOTHESIS; COMPARATIVE MOLECULAR FIELD ANALYSIS; COMPARATIVE MOLECULAR SIMILARITY INDICES ANALYSIS; MOLECULAR MODEL; PARTIAL LEAST SQUARES REGRESSION; PHARMACOPHORE; PREDICTIVE VALIDITY; QUANTITATIVE STRUCTURE ACTIVITY RELATION; THREE DIMENSIONAL IMAGING;

EID: 78650176724     PISSN: 10542523     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00044-009-9261-1     Document Type: Article

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