Deoxycholate hydrogels of betamethasone-17-valerate intended for topical use: In vitro and in vivo evaluation

International Journal of Pharmaceutics

Volumn 403, Issue 1-2, 2011, Pages 123-129

  Şenyiit, Taner ^a   Tekmen, Işil ^b   Sönmez, Ülker ^b   Santi, Patrizia ^c   Özer, Özgen ^a  

^a EGE UNIVERSITY   (Turkey)

^b DOKUZ EYLUL UNIVERSITY   (Turkey)

^c UNIVERSITY OF PARMA   (Italy)

Author keywords

Anti inflammatory activity; Betamethasone valerate; Skin permeation enhancement; Sodium deoxycholate gel; Texture profile analysis

Indexed keywords

BETAMETHASONE VALERATE; DEOXYCHOLATE SODIUM;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG FORMULATION; DRUG PENETRATION; DRUG STABILITY; FLOW KINETICS; HYDROGEL; IN VITRO STUDY; IN VIVO STUDY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SHEAR RATE; SKIN DEFECT; SKIN IRRITATION; SKIN PERMEABILITY; VISCOSITY;

ADMINISTRATION, TOPICAL; ANIMALS; ANTI-INFLAMMATORY AGENTS; BETAMETHASONE 17-VALERATE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DEOXYCHOLIC ACID; DISEASE MODELS, ANIMAL; DRUG CARRIERS; DRUG STABILITY; EDEMA; HYDROGELS; MALE; MECHANICAL PHENOMENA; RATS; RATS, WISTAR; RHEOLOGY; SKIN; SKIN ABSORPTION;

EID: 78650173143     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2010.10.036     Document Type: Article

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