Modulation of radiation induced changes in nucleic acid content of liver of Swiss albino mouse by tinospora cordifolia (miers)

Iranian Journal of Radiation Research

Volumn 8, Issue 3, 2010, Pages 179-185

  Arya, S ^a   Sharma, J ^a  

^a UNIVERSITY OF RAJASTHAN   (India)

Author keywords

DNA; Liver; Radioprotection; RNA; Tinospora cordifolia

Indexed keywords

TINOSPORA CORDIFOLIA EXTRACT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DNA CONTENT; DNA DAMAGE; DNA REPAIR; DRUG ACTIVITY; DRUG EFFICACY; GAMMA RADIATION; LIVER; MALE; MOUSE; MUTAGENESIS; NONHUMAN; OXIDATIVE STRESS; PROTEIN MODIFICATION; RADIATION DOSE; RADIATION EXPOSURE; RADIATION INJURY; RADIATION PROTECTION; RNA ANALYSIS;

EID: 78650160678     PISSN: 23223243     EISSN: 17284562     Source Type: Journal    
DOI: None     Document Type: Article

References (21)

1. Bhattacharya SK, Satyam K, Ghosal S (1996) Antioxidant activity of glycowithanolides from Withania somnifera. Int J of Expl Biol, 35:236-239.
2. Lee JH, Jong CP, Jae Sc (1996) Antioxidant activity of Ecklonia stolonifera. Archives of Pharmacol Res, 3:223-227.
3. Yen, Grow CS, Chi W, Pinder D (1996) Extraction and identification of components from the level of Mulbery. J of Agri and Food Chem, 44: 1687-1690.
4. Singh KK and Maheshwari JK (1983) Traditional phyto-therapy amongst the tribals of Varanasi District, UP J Econ Tax Bot U, 4:829.
5. Kritikar KR and Basu BD (1933) Indian medicinal plants. Lalit Mohan Basu, Leader Road, Allahabad, 2pp. 77.
6. Ceriotti G (1952) The microchemical determination of deoxyribonucleic acid. J Biol Chem, 198: 297.
7. Ceriotti G (1955) Determination of nucleic acids in animals tissue. J Bid Chem, 214:59.
8. Fischer RA (1946) Statistical methods for research workers. 10th Ed. London, Oliver and Boyd.
9. Bourke GJ, Daly LE, Mc Gilvary J (1985) Interpretation and uses of medical statistics, 3Edn. Blackwell scientific Publ. Oxford.
10. Semenov MA, Bol bukh T, Krasnitskaia AA and Maleev Via (1994) Hydration and structural state of liver DNA of rats exposed to radiation in the Chernobyl AES Zone. Radiat Biol Radioecol, 34: 328-35.
11. Bhatavadekar JM, Babu KA, Shah VC (1977) Effect of low dose X-irradiation on nucleic acids and protein contents of guinea pig, rat and mouse tissues. Ind J Exp Biol, 15: 980-985.
12. Dave VP, Patil MS, Pandey VN, Pradhan DS (1991) DNA Synthesis in nucleic and nuclear matrics of regeneration of rat liver: effect of whole body gamma irradiation. Ra-diat Environ Biophys, 30: 267-276.
13. Mitchell JB and Krishna MC (2002) Nitroxides as radiation protector. Mit Med, 167 (Suppl): 49-50.
14. Kutsyi MP, Kuznetsova EA, Gluiaeva NA, Gaziev AI (2002) Effect of gamma radiation and mitochondrial apoptogenic factors on nuclear protease activity. Radiat Biol radioecol,42:357-363.
15. Strazhevskaia NB and Struchkov VA (1988) Effect of chalone on the DNA supramolecular complex in rat and their survival following gamma irradiation. Radiobi-ologiia, 28:199-200.
16. Hakova H and Mususova E (1996) Therapentical effect of Silymarin on nucleic acids in the various organs of rats after radiation injury. Radiat. Biol. Radioecol, 36: 365-370.
17. Cong XL, Wang X L, Su Q, Yan S, Cai L (1998) Protective effects of extracted human liver RNA, a known inter-feron inducer, against radiation induced cytogenetic damage in male mice. Toxicol Lett, 94:189-198.
18. Ganesh CJ and Majeshwar SB (2003) Treatment of Mice with a herbal preparation (Mental) protects against radiation induced mortality. Phytotherapy Res, 17: 876-881.
19. Sies H and Stahl W (1995) Vitamins E and C,β-carotene and other carotenoids as antioxidants. Ann J Clin Nutr, 62 (Suppl): 1311S-21S.
20. Sies H (1986) Biochemistry of oxidative stress. Angeo Chem Int, 25:1058-1071.
21. Piryor WA and Godber SS (1991) Noninvasive measures of oxidative stress status in humans. Free Radiac Biol Med, 10:177-184.