Cognitive stimulation therapy in the treatment of neuropsychiatric symptoms in Alzheimer's disease: A randomized controlled trial

Clinical Rehabilitation

Volumn 24, Issue 12, 2010, Pages 1102-1111

  Niu, Yi Xuan ^a   Tan, Ji Ping ^a   Guan, Jin Qun ^a   Zhang, Zeng Qiang ^a   Wang, Lu Ning ^a  

^a CHINESE PLA GENERAL HOSPITAL   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLINESTERASE INHIBITOR; DONEPEZIL; INDAN DERIVATIVE; PIPERIDINE DERIVATIVE;

AGED; ALZHEIMER DISEASE; ARTICLE; BEHAVIOR; CHINA; CLINICAL TRIAL; COGNITIVE THERAPY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; EXECUTIVE FUNCTION; FEMALE; HUMAN; MALE; METHODOLOGY; MULTIMODALITY CANCER THERAPY; RANDOMIZED CONTROLLED TRIAL; SHORT TERM MEMORY; SINGLE BLIND PROCEDURE;

AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; BEHAVIORAL SYMPTOMS; CHINA; CHOLINESTERASE INHIBITORS; COGNITIVE THERAPY; COMBINED MODALITY THERAPY; EXECUTIVE FUNCTION; FEMALE; HUMANS; INDANS; MALE; MEMORY, SHORT-TERM; PIPERIDINES; SINGLE-BLIND METHOD;

EID: 78650137357     PISSN: 02692155     EISSN: 14770873     Source Type: Journal    
DOI: 10.1177/0269215510376004     Document Type: Article

References (42)

1. Cummings JL Alzheimer's disease. N Engl J Med 2004 ; 351: 56-67.
2. Mega MS, Cummings JL, Fiorello T., Gornbein J. The spectrum of behavioral changes in Alzheimer's disease. Neurology 1996 ; 46: 130-5. (Pubitemid 26156117)
3. Lyketsos CG, Lopez O., Jones B., Fitzpatrick AL, Breitner J., DeKosky S. Prevalence of neuropsychiatric symptoms in dementia and mild cognitive impairment: results from the cardiovascular health study. JAMA 2002 ; 288: 1475-83.
4. Cummings JL Behavioral and neuropsychiatric outcomes in Alzheimer's disease. CNS Spectr 2005 ; 10: 22-5. (Pubitemid 41784924)
5. Tatsumi H., Nakaaki S., Torii K. et al. Neuropsychiatric symptoms predict change in quality of life of Alzheimer disease patients: a two-year follow-up study. Psychiatry Clin Neurosci 2009 ; 3: 374-84.
6. Shin IS, Carter M., Masterman D., Fairbanks L., Cummings JL Neuropsychiatric symptoms and quality of life in Alzheimer disease. Am J Geriatr Psychiatry 2005 ; 13: 469-74.
7. Coen RF, Swanwick GR, O'Boyle CA, Coakley D. Behaviour disturbance and other predictors of carer burden in Alzheimer's disease. Int J Geriatr Psychiatry 1997 ; 12: 331-6. (Pubitemid 27148454)
8. Chan DC, Kasper JD, Black BS, Rabins PV Presence of behavioral and psychological symptoms predicts nursing home placement in community-dwelling elders with cognitive impairment in univariate but not multivariate analysis. J Gerontol A Biol Sci Med Sci 2003 ; 58: 548-54. (Pubitemid 36702693)
9. Phillips VL, Diwan S. The incremental effect of dementia-related problem behaviors on the time to nursing home placement in poor, frail, demented older people. J Am Geriatr Soc 2003 ; 51: 188-93. (Pubitemid 36205847)
10. Clare L., Woods RT, Moniz Cook ED et al. Cognitive rehabilitation and cognitive training for early-stage Alzheimer's disease and vascular dementia. Cochrane Database Syst Rev 2003 ; 4: CD003260.
11. Sitzer DI, Twamley EW, Jeste DV Cognitive training in Alzheimer's disease: a meta-analysis of the literature. Acta Psychiatr Scand 2006 ; 114: 75-90. (Pubitemid 44034266)
12. Spector A., Woods B., Orrell M. Cognitive stimulation for the treatment of Alzheimer's disease. Expert Rev Neurother 2008 ; 8: 751-7. (Pubitemid 351656826)
13. Bottino CM, Carvalho IA, Alvarez AM et al. Cognitive rehabilitation combined with drug treatment in Alzheimer's disease patients: a pilot study. Clin Rehabil 2005 ; 19: 861-9. (Pubitemid 41723794)
14. Loewenstein DA, Acevedo A., Czaja SJ, Duara R. Cognitive rehabilitation of mildly impaired Alzheimer's disease patients on cholinesterase inhibitors. Am J Geriatr Psychiatry 2004 ; 12: 395-402. (Pubitemid 38878859)
15. Rabins PV, Blacker D. et al., APA Work Group on Alzheimer's Disease and other Dementias. American Psychiatric Association practice guideline for the treatment of patients with Alzheimer's disease and other dementias. Second edition. Am J Psychiatry 2007 ; 164 (suppl): 5-56.
16. Spector A., Orrell M., Davies S., Woods B. Reality orientation for dementia. Cochrane Library. Vol 3. Oxford, UK: Update Software, 2002.
17. Onder G., Zanetti O., Giacobini E. et al. Reality orientation therapy combined with cholinesterase inhibitor in Alzheimers disease randomised controlled trial. Br J Psychiatry 2005 ; 187: 450-5. (Pubitemid 41546575)
18. Dietch JT, Hewett LJ, Jones S. Adverse effects of reality orientation. J Am Geriatr Soc 1989 ; 37: 974-6. (Pubitemid 19253219)
19. Raggi A., Iannaccone S., Marcone A. et al. The effects of a comprehensive rehabilitation program of Alzheimer's disease in a hospital setting. Behav Neurol 2007 ; 18: 1-6. (Pubitemid 46333655)
20. Talassi E., Guerreschi M., Feriani M., Fedi V., Bianchetti A., Trabucchi M. Effectiveness of a cognitive rehabilitation program in mild dementia (MD) and mild cognitive impairment (MCI): a case control study. Arch Gerontol Geriatr 2007 ; 44: 391-9. (Pubitemid 46273738)
21. Cummings JL, Mega M., Gray K., Rosenberg-Thompson S., Carusi DA, Gornbein J. The Neuropsychiatric Inventory: comprehensive assessment of psychopathology in dementia. Neurology 1994 ; 44: 2308-14. (Pubitemid 24382728)
22. McKhann G., Drachman D., Folstein M., Katzman R., Price D., Stadlan EM Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology 1984 ; 34: 939-44. (Pubitemid 14076461)
23. Clark CM, Sheppard L., Fillenbaum GG et al. Variability in annual Mini-Mental State Examination score in patients with probable Alzheimer disease: a clinical perspective of data from the Consortium to Establish a Registry for Alzheimer's Disease. Arch Neurol 1999 ; 56: 857-62. (Pubitemid 29318912)
24. Clare L., Wilson BA, Carter G., Breen K., Gosses A., Hodges JR Intervening with everyday memory problems in dementia of Alzheimer type: an errorless learning approach. J Clin Exp Neuropsychol 2000 ; 22: 132-46. (Pubitemid 30114650)
25. Clare L., Jones RS Errorless learning in the rehabilitation of memory impairment: a critical review. Neuropsychol Rev 2008 ; 18: 1-23.
26. Cohen-Mansfeld J. Nonpharmacologic interventions for inappropriate behaviors in dementia: a review, summary, and critique. Am J Geriatric Psychiatry 2001 ; 9: 361-81.
27. Runci S., Doyle C., Redman J. An empirical test of language-relevant interventions on dementia. Int Psychogeriatr 1999 ; 11: 301-11. (Pubitemid 29466174)
28. Feldman H., Gauthier S., Hecker J. et al. A 24-week, randomized, double-blind study of donepezil in moderate to severe Alzheimer's disease. Neurology 2001 ; 57: 613-620. (Pubitemid 32782987)
29. Cummings JL, Mackell J., Kaufer D. Behavioral effects of current Alzheimer's disease treatments: a descriptive review. Alzheimers Dement 2008 ; 4: 49-60.
30. Benoit M., Clairet S., Koulibaly PM Brain perfusion correlates of the apathy inventory dimensions of Alzheimer's disease. Int J Geriatr Psychiatry 2004 ; 19: 864-9. (Pubitemid 39242892)
31. Hirono N., Mori E., Ishii K. et al. Frontal lobe hypometabolism and depression in Alzheimer's disease. Neurology 1998 ; 50: 380-3. (Pubitemid 28119774)
32. Holthoff VA, Beuthien-Baumann B., Kalbe E. et al. Regional cerebral metabolism in early Alzheimer's disease with clinically significant apathy or depression. Biol Psychiatry 2005 ; 57: 412-21. (Pubitemid 40215772)
33. Loose R., Kaufmann C., Auer DP, Lange KW Human prefrontal and sensory cortical activity during divided attention tasks. Hum Brain Mapp 2003 ; 18: 249-59. (Pubitemid 36403013)
34. Harrison BJ, Shaw M., Yücel M. et al. Functional connectivity during Stroop task performance. Neuroimage 2005 ; 24: 181-91. (Pubitemid 39611038)
35. Kuzis G., Sabe L., Tiberti C., Dorrego F., Starkstein SE Neuropsychological correlates of apathy and depression in patients with dementia. Neurology 1999 ; 52: 1403-7. (Pubitemid 29190531)
36. McPherson S., Fairbanks L., Tiken S., Cummings JL, Back-Madruga C. Apathy and executive function in Alzheimer's disease. J Int Neuropsychol Soc 2002 ; 8: 373-81.
37. Nakaaki S., Murata Y., Sato J. et al. Greater impairment of ability in the divided attention task is seen in Alzheimer's disease patients with depression than in those without depression. Dement Geriatr Cogn Disord 2007 ; 23: 231-40. (Pubitemid 46496809)
38. Elfgren CI, Risberg J. Lateralized frontal blood flow increases during fluency tasks: influence of cognitive strategy. Neuropsychologia 1998 ; 36: 505-12. (Pubitemid 28342186)
39. Gourovitch ML, Kirkby BS, Goldberg TE et al. A comparison of rCBF patterns during letter and semantic fluency. Neuropsychology 2000 ; 14: 353-60.
40. Baudic S., Barba GD, Thibaudet MC, Smagghe A., Remy P., Traykov L. Executive function deficits in early Alzheimer's disease and their relations with episodic memory. Arch Clin Neuropsychol 2006 ; 21: 15-21. (Pubitemid 41802923)
41. Alvarez JA, Emory E. Executive function and the frontal lobes: a meta-analytic review. Neuropsychol Rev 2006 ; 16: 17-42. (Pubitemid 43954075)
42. Balestrieri M. Expressions of depression in Alzheimer's disease. The current scientific debate. Epidemiol Psychiatr Soc 2000 ; 9: 126-39. (Pubitemid 32002028)