Appropriate within-subjects statistical models for the analysis of baroreflex sensitivity

Clinical Physiology and Functional Imaging

Volumn 31, Issue 1, 2011, Pages 80-82

  Atkinson, Greg ^a   Batterham, Alan M ^b   Jones, Helen ^a   Taylor, Chloe E ^a   Willie, Chris K ^c   Tzeng, Yu Chieh ^d  

^a LIVERPOOL JOHN MOORES UNIVERSITY   (United Kingdom)

^b TEESSIDE UNIVERSITY   (United Kingdom)

^c UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^d UNIVERSITY OF OTAGO   (New Zealand)

Author keywords

Least squares regression; Linear mixed models; Repeated measures; Statistical assumptions; Summary measures

Indexed keywords

NITROPRUSSIDE SODIUM;

ARTICLE; BAROREFLEX SENSITIVITY; CONTROLLED STUDY; HUMAN; HUMAN EXPERIMENT; NORMAL HUMAN; PRESSORECEPTOR REFLEX; PRIORITY JOURNAL; RECEPTOR SENSITIVITY; REGRESSION ANALYSIS; SENSITIVITY ANALYSIS; STATISTICAL ANALYSIS; STATISTICAL MODEL; SYSTOLIC BLOOD PRESSURE;

BAROREFLEX; BLOOD PRESSURE; HEART RATE; HUMANS; LINEAR MODELS; MODELS, BIOLOGICAL;

EID: 78650114510     PISSN: 14750961     EISSN: 1475097X     Source Type: Journal    
DOI: 10.1111/j.1475-097X.2010.00974.x     Document Type: Article

References (11)

1. Bland JM, Altman DG. Calculating correlation coefficients with repeated observations: part 1-correlation within subjects. Br Med J (1995); 310: 446.
2. Cnaan A, Laird NM, Slasor P. Using the general linear mixed model to analyse unbalanced repeated measures and longitudinal data. Stat Med (1997); 16: 2349-2380.
3. Lazic SE. The problem of pseudoreplication in neuroscientific studies: is it affecting your analysis? BMC Neurosci (2010); 11: 1-17.
4. Ler ASH, Cohen MA, Taylor JA. A planar elliptical model of cardio-vagal hysteresis. Physiol Meas (2010); 31: 857-873.
5. Matthews JN. A refinement to the analysis of serial data using summary measures. Stat Med (1993); 12: 27-37.
6. Matthews JN, Altman DG, Campbell MJ, Royston P. Analysis of serial measurements in medical research. BMJ (1990); 300: 230-235.
7. Nieminen T, Kahonen M, Laitinen T, Koobi T. Computational and physiological background of the baroreflex sensitivity. Clin Physiol Funct Imaging (2010); 30: 220-222.
8. Olufsen MS, Tran HT, Ottesen JT, Research Experiences for Undergraduates Program, Lipsitz LA, Novak V. Modeling baroreflex regulation of heart rate during orthostatic stress. Am J Physiol Regul Integr Comp Physiol (2006); 291: R1355-R1368.
9. Overall JE, Tonidandel S. A two-stage analysis of repeated measurements with dropouts and/or intermittent missing data. J Clin Psychol (2006); 62: 285-291.
10. Studinger P, Goldstein R, Taylor JA. Mechanical and neural contributions to hysteresis in the cardiac vagal limb of the arterial baroreflex. J Physiol (2007); 583: 1041-1048.
11. Zar JH. Biostatistical Analysis (1999). Prentice Hall, London.