-
1
-
-
34548379435
-
The significance of mitochondrial toxicity testing in drug development
-
DOI 10.1016/j.drudis.2007.07.013, PII S1359644607002796
-
Dykens JA, Will Y.: The significance of mitochondrial toxicity testing in drug development. Drug Discov Today 2007 ; 12: 777-785. (Pubitemid 47362789)
-
(2007)
Drug Discovery Today
, vol.12
, Issue.17-18
, pp. 777-785
-
-
Dykens, J.A.1
Will, Y.2
-
2
-
-
70449484092
-
The role of mitochondria in health and disease
-
Johannsen DL, Ravussin E.: The role of mitochondria in health and disease. Curr Opin Pharmacol 2009 ; 9: 780-786.
-
(2009)
Curr Opin Pharmacol
, vol.9
, pp. 780-786
-
-
Johannsen, D.L.1
Ravussin, E.2
-
3
-
-
71549121668
-
The failure of mitochondria leads to neurodegeneration: Do mitochondria need a jump start
-
Lee J., Boo JH, Ryu H.: The failure of mitochondria leads to neurodegeneration: do mitochondria need a jump start ? Adv Drug Deliv Rev 2009 ; 61: 1316-1323.
-
(2009)
Adv Drug Deliv Rev
, vol.61
, pp. 1316-1323
-
-
Lee, J.1
Boo, J.H.2
Ryu, H.3
-
4
-
-
0033971898
-
Mitochondria and neuronal survival
-
Nicholls DG, Budd SL: Mitochondria and neuronal survival. Physiol Rev 2000 ; 80: 315-360.
-
(2000)
Physiol Rev
, vol.80
, pp. 315-360
-
-
Nicholls, D.G.1
Budd, S.L.2
-
5
-
-
33646811861
-
Mitochondrial membrane potential and ischemic neuronal death
-
Iijima T.: Mitochondrial membrane potential and ischemic neuronal death. Neurosci Res 2006 ; 55: 234-243.
-
(2006)
Neurosci Res
, vol.55
, pp. 234-243
-
-
Iijima, T.1
-
6
-
-
34250705186
-
The mitochondrial permeability transition in neurologic disease
-
Norenberg MD, Rao KVR: The mitochondrial permeability transition in neurologic disease. Neurochem Int 2007 ; 50: 983-997.
-
(2007)
Neurochem Int
, vol.50
, pp. 983-997
-
-
Norenberg, M.D.1
Kvr, R.2
-
7
-
-
34250683102
-
Evaluating mitochondrial membrane potential in cells
-
Solaini G., Sgarbi G., Lenaz G., Baracca A.: Evaluating mitochondrial membrane potential in cells. Biosci Rep 2007 ; 27: 11-21.
-
(2007)
Biosci Rep
, vol.27
, pp. 11-21
-
-
Solaini, G.1
Sgarbi, G.2
Lenaz, G.3
Baracca, A.4
-
8
-
-
0036670612
-
Development of a high throughput screening assay for mitochondrial membrane potential in living cells
-
Huang SG: Development of a high throughput screening assay for mitochondrial membrane potential in living cells. J Biomol Screen 2002 ; 7: 383-389.
-
(2002)
J Biomol Screen
, vol.7
, pp. 383-389
-
-
Huang, S.G.1
-
9
-
-
0036435533
-
High-throughput measurement of mitochondrial membrane potential in a neural cell line using a fluorescence plate reader
-
Wong A., Cortopassi GA: High-throughput measurement of mitochondrial membrane potential in a neural cell line using a fluorescence plate reader. Biochem Biophys Res Commun 2002 ; 298: 750-754.
-
(2002)
Biochem Biophys Res Commun
, vol.298
, pp. 750-754
-
-
Wong, A.1
Cortopassi, G.A.2
-
10
-
-
0035672274
-
High throughput fluorescence assays for the measurement of mitochondrial activity in intact human neuroblastoma cells
-
Woollacott AJ, Simpson PB: High throughput fluorescence assays for the measurement of mitochondrial activity in intact human neuroblastoma cells. J Biomol Screen 2001 ; 6: 413-420.
-
(2001)
J Biomol Screen
, vol.6
, pp. 413-420
-
-
Woollacott, A.J.1
Simpson, P.B.2
-
11
-
-
0036242162
-
High-throughput assessment of mitochondrial membrane potential in situ using fluorescence resonance energy transfer
-
Dykens JA, Fleck B., Ghosh S., Lewis M., Velicelebi G., Ward MW: High-throughput assessment of mitochondrial membrane potential in situ using fluorescence resonance energy transfer. Mitochondrion 2002 ; 1: 461-473.
-
(2002)
Mitochondrion
, vol.1
, pp. 461-473
-
-
Dykens, J.A.1
Fleck, B.2
Ghosh, S.3
Lewis, M.4
Velicelebi, G.5
Ward, M.W.6
-
12
-
-
0035881593
-
Screening assays for the mitochondrial permeability transition using a fluorescence multiwell plate reader
-
Blattner JR, He L., Lemasters JJ: Screening assays for the mitochondrial permeability transition using a fluorescence multiwell plate reader. Anal Biochem 2001 ; 295: 220-226.
-
(2001)
Anal Biochem
, vol.295
, pp. 220-226
-
-
Blattner, J.R.1
He, L.2
Lemasters, J.J.3
-
13
-
-
0019883391
-
The 2-(dimethylaminostyryl)-1-methylpyridinium cation as indicator of the mitochondrial membrane potential
-
Mewes HW, Rafael J.: The 2-(dimethylaminostyryl)-1-methylpyridinium cation as indicator of the mitochondrial membrane potential. FEBS Lett 1981 ; 131: 7-10.
-
(1981)
FEBS Lett
, vol.131
, pp. 7-10
-
-
Mewes, H.W.1
Rafael, J.2
-
14
-
-
0016883750
-
Dimethylaminostyrylmethylpyridiniumiodine (daspmi) as a fluorescent probe for mitochondria in situ
-
Bereiter-Hahn J.: Dimethylaminostyrylmethylpyridiniumiodine (daspmi) as a fluorescent probe for mitochondria in situ. Biochim Biophys Acta 1976 ; 423: 1-14.
-
(1976)
Biochim Biophys Acta
, vol.423
, pp. 1-14
-
-
Bereiter-Hahn, J.1
-
15
-
-
0020830517
-
Fluorimetry of mitochondria in cells vitally stained with DASPMI or rhodamine 6 GO
-
Bereiter-Hahn J., Seipel KH, Voth M., Ploem JS: Fluorimetry of mitochondria in cells vitally stained with DASPMI or rhodamine 6 GO. Cell Biochem Funct 1983 ; 1: 147-155.
-
(1983)
Cell Biochem Funct
, vol.1
, pp. 147-155
-
-
Bereiter-Hahn, J.1
Seipel, K.H.2
Voth, M.3
Ploem, J.S.4
-
16
-
-
15244348931
-
Determination of cell concentration in a plant cell suspension using a fluorescence microplate reader
-
Lamboursain L., Jolicoeur M.: Determination of cell concentration in a plant cell suspension using a fluorescence microplate reader. Plant Cell Rep 2005 ; 23: 665-672.
-
(2005)
Plant Cell Rep
, vol.23
, pp. 665-672
-
-
Lamboursain, L.1
Jolicoeur, M.2
-
17
-
-
3042550340
-
Differential effects of typical and atypical neuroleptics on mitochondrial function in vitro
-
Modica-Napolitano JS, Lagace CJ, Brennan WA, Aprille JR: Differential effects of typical and atypical neuroleptics on mitochondrial function in vitro. Arch Pharm Res 2003 ; 26: 951-959.
-
(2003)
Arch Pharm Res
, vol.26
, pp. 951-959
-
-
Modica-Napolitano, J.S.1
Lagace, C.J.2
Brennan, W.A.3
Aprille, J.R.4
-
18
-
-
34447577912
-
Circumventing the Crabtree effect: Replacing media glucose with galactose increases susceptibility of HepG2 cells to mitochondrial toxicants
-
Marroquin LD, Hynes J., Dykens JA, Jamieson JD, Will Y.: Circumventing the Crabtree effect: replacing media glucose with galactose increases susceptibility of HepG2 cells to mitochondrial toxicants. Toxicol Sci 2007 ; 97: 539-547.
-
(2007)
Toxicol Sci
, vol.97
, pp. 539-547
-
-
Marroquin, L.D.1
Hynes, J.2
Dykens, J.A.3
Jamieson, J.D.4
Will, Y.5
-
19
-
-
0037320046
-
Actions of ionomycin, 4-BrA23187 and a novel electrogenic Ca2+ ionophore on mitochondria in intact cells
-
Abramov AY, Duchen MR: Actions of ionomycin, 4-BrA23187 and a novel electrogenic Ca2+ ionophore on mitochondria in intact cells. Cell Calcium 2003 ; 33: 101-112.
-
(2003)
Cell Calcium
, vol.33
, pp. 101-112
-
-
Abramov, A.Y.1
Duchen, M.R.2
-
20
-
-
0005448587
-
Cobalt chloride induces apoptosis in Chinese hamster ovary cells and zinc chloride protects against cobalt-induced apoptosis
-
Tatsumi H.: Cobalt chloride induces apoptosis in Chinese hamster ovary cells and zinc chloride protects against cobalt-induced apoptosis. J Kyushu Dent Soc 1999 ; 53: 13-28.
-
(1999)
J Kyushu Dent Soc
, vol.53
, pp. 13-28
-
-
Tatsumi, H.1
-
21
-
-
0032104130
-
Mitochondrial function impairment induced by amyloid beta-peptide on PC12 cells
-
Pereira C., Santos MS, Oliveira C.: Mitochondrial function impairment induced by amyloid beta-peptide on PC12 cells. Neuroreport 1998 ; 9: 1749-1755.
-
(1998)
Neuroreport
, vol.9
, pp. 1749-1755
-
-
Pereira, C.1
Santos, M.S.2
Oliveira, C.3
-
22
-
-
56049092327
-
How DASPMI reveals mitochondrial membrane potential: Fluorescence decay kinetics and steady-state anisotropy in living cells
-
Ramadass R., Bereiter-Hahn J.: How DASPMI reveals mitochondrial membrane potential: fluorescence decay kinetics and steady-state anisotropy in living cells. Biophys J 2008 ; 95: 4068-4076.
-
(2008)
Biophys J
, vol.95
, pp. 4068-4076
-
-
Ramadass, R.1
Bereiter-Hahn, J.2
-
23
-
-
0032705639
-
A rapid method for the evaluation of compounds with mitochondria- protective properties
-
Nuydens R., Novalbos J., Dispersyn G., Weber C., Borgers M., Geerts H.: A rapid method for the evaluation of compounds with mitochondria-protective properties. J Neurosci Methods 1999 ; 92: 153-159.
-
(1999)
J Neurosci Methods
, vol.92
, pp. 153-159
-
-
Nuydens, R.1
Novalbos, J.2
Dispersyn, G.3
Weber, C.4
Borgers, M.5
Geerts, H.6
-
24
-
-
0345120940
-
Measurement of mitochondrial membrane potential using fluorescent rhodamine derivatives
-
Scaduto RC, Jr, Grotyohann LW: Measurement of mitochondrial membrane potential using fluorescent rhodamine derivatives. Biophys J 1999 ; 76: 469-477.
-
(1999)
Biophys J
, vol.76
, pp. 469-477
-
-
Scaduto Jr., R.C.1
Grotyohann, L.W.2
-
25
-
-
0025830873
-
J-aggregate formation of a carbocyanine as a quantitative fluorescent indicator of membrane potential
-
Reers M., Smith TW, Chen LB: J-aggregate formation of a carbocyanine as a quantitative fluorescent indicator of membrane potential. Biochemistry 1991 ; 30: 4480-4486.
-
(1991)
Biochemistry
, vol.30
, pp. 4480-4486
-
-
Reers, M.1
Smith, T.W.2
Chen, L.B.3
-
26
-
-
33744952060
-
Nicholls DG: Simultaneous monitoring of ionophore- and inhibitor-mediated plasma and mitochondrial membrane potential changes in cultured neurons
-
Nicholls DG: Simultaneous monitoring of ionophore- and inhibitor-mediated plasma and mitochondrial membrane potential changes in cultured neurons. J Biol Chem 2006 ; 281: 14864-14874.
-
(2006)
J Biol Chem
, vol.281
, pp. 14864-14874
-
-
-
27
-
-
70350325187
-
Oxidative stress-induced necrotic cell death via mitochondria-dependent burst of reactive oxygen species
-
Choi K., Kim J., Kim GW, Choi C.: Oxidative stress-induced necrotic cell death via mitochondria-dependent burst of reactive oxygen species. Curr Neurovasc Res 2009 ; 6: 213-222.
-
(2009)
Curr Neurovasc Res
, vol.6
, pp. 213-222
-
-
Choi, K.1
Kim, J.2
Kim, G.W.3
Choi, C.4
-
28
-
-
0036261394
-
Thioridazine interacts with the membrane of mitochondria acquiring antioxidant activity toward apoptosis-potentially implicated mechanisms
-
Rodrigues T., Santos AC, Pigoso AA, Mingatto FE, Uyemura SA, Curti C.: Thioridazine interacts with the membrane of mitochondria acquiring antioxidant activity toward apoptosis-potentially implicated mechanisms. Br J Pharmacol 2002 ; 136: 136-142.
-
(2002)
Br J Pharmacol
, vol.136
, pp. 136-142
-
-
Rodrigues, T.1
Santos, A.C.2
Pigoso, A.A.3
Mingatto, F.E.4
Uyemura, S.A.5
Curti, C.6
-
29
-
-
34547850670
-
NOX4 activity is determined by mRNA levels and reveals a unique pattern of ROS generation
-
Serrander L., Cartier L., Bedard K., Banfi B., Lardy B., Plastre O., et al. NOX4 activity is determined by mRNA levels and reveals a unique pattern of ROS generation. Biochem J 2007 ; 406: 105-114.
-
(2007)
Biochem J
, vol.406
, pp. 105-114
-
-
Serrander, L.1
Cartier, L.2
Bedard, K.3
Banfi, B.4
Lardy, B.5
Plastre, O.6
-
30
-
-
78650129167
-
710: HIF-1[alpha] activation by cobalt hyperpolarizes and fragments mitochondria in pulmonary artery smooth muscle cells creating a "pulmonary arterial hypertension" phenotype as seen in fawn-hooded rats
-
Toth PT, Zhang HJ, Rehman J., Zhang Y., Archer SL: 710: HIF-1[alpha] activation by cobalt hyperpolarizes and fragments mitochondria in pulmonary artery smooth muscle cells creating a "pulmonary arterial hypertension" phenotype as seen in fawn-hooded rats. J Heart Lung Transplantation 2009 ; 28: S312 - S313.
-
(2009)
J Heart Lung Transplantation
, vol.28
-
-
Toth, P.T.1
Zhang, H.J.2
Rehman, J.3
Zhang, Y.4
Archer, S.L.5
-
31
-
-
0035877175
-
Cobalt chloride induces PC12 cells apoptosis through reactive oxygen species and accompanied by AP-1 activation
-
Zou W., Yan M., Xu W., Huo H., Sun L., Zheng Z., et al. Cobalt chloride induces PC12 cells apoptosis through reactive oxygen species and accompanied by AP-1 activation. J Neurosci Res 2001 ; 64: 646-653.
-
(2001)
J Neurosci Res
, vol.64
, pp. 646-653
-
-
Zou, W.1
Yan, M.2
Xu, W.3
Huo, H.4
Sun, L.5
Zheng, Z.6
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