Differential effect of telmisartan and amlodipine on monocyte chemoattractant protein-1 and peroxisome proliferator-activated receptor-gamma gene expression in peripheral monocytes in patients with essential hypertension

American Journal of Cardiology

Volumn 107, Issue 1, 2011, Pages 59-63

  Marketou, Maria E ^a   Kontaraki, Joanna E ^a   Tsakountakis, Nikolaos A ^b   Zacharis, Evangelos A ^b   Kochiadakis, George E ^a   Arfanakis, Dimitris A ^a   Parthenakis, Frangiskos ^a   Chlouverakis, Gregory ^c   Vardas, Panos E ^a  

^a UNIVERSITY HOSPITAL OF HERAKLION   (Greece)

^b Kastelli Health Center   (Greece)

^c UNIVERSITY OF CRETE   (Greece)

Author keywords

[No Author keywords available]

Indexed keywords

AMLODIPINE; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; TELMISARTAN;

ADULT; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; DRUG EFFECT; ESSENTIAL HYPERTENSION; FEMALE; GENE EXPRESSION; HUMAN; LEUKOCYTE ACTIVATION; MALE; MONOCYTE; PRIORITY JOURNAL; PROTEIN DETERMINATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ANALYSIS;

AMLODIPINE; ANTIHYPERTENSIVE AGENTS; BENZIMIDAZOLES; BENZOATES; CHEMOKINE CCL2; FEMALE; GENE EXPRESSION; HUMANS; HYPERTENSION; MALE; MIDDLE AGED; MONOCYTES; PPAR GAMMA; SEVERITY OF ILLNESS INDEX;

EID: 78650079867     PISSN: 00029149     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.amjcard.2010.08.048     Document Type: Article

References (31)

1. S. Riou, B. Mees, B. Esposito, R. Merval, J. Vilar, D. Stengel, E. Ninio, R. van Haperen, R. de Crom, A. Tedgui, and S. Lehoux High pressure promotes monocyte adhesion to the vascular wall Circ Res 100 2007 1226 1233
2. K.F. Hilgers Monocytes/macrophages in hypertension J Hypertens 20 2002 593 596
3. L.A. Moraes, L. Piqueras, and D. Bishop-Bailey Peroxisome proliferator-activated receptors and inflammation Pharmacol Ther 110 2006 371 385
4. G. Mancia, G. de Backer, A. Dominiczak, R. Cifkova, R. Fagard, G. Germano, G. Grassi, A.M. Heagerty, S.E. Kjeldsen, S. Laurent, K. Narkiewicz, L. Ruilope, A. Rynkiewicz, R.E. Schmieder, H.A. Boudier, and A. Zanchetti Guidelines for the Management of Arterial Hypertension The Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC) J Hypertens 25 2007 1751 1762
5. M. Schupp, J. Janke, J. Clasen, T. Unger, and U. Kintscher Angiotensin type 1 receptor blockers induce peroxisome proliferator activated receptor-gamma activity Circulation 109 2004 2054 2057
6. D. Zapolska-Donar, A. Siennicka, K. Chestowski, K. Widecka, I. Goracy, M. Haasa, B. Mashalinski, and M. Naruszewicz Is there an association between angiotensin-converting enzyme gene polymorphism and functional activation of monocytes and macrophage in young patients with essential hypertension? J Hypertens 24 2006 1565 1573
7. L. Gu, S.C. Tseng, and B.J. Rollins Monocyte chemoattractant protein-1 Chem Immunol 72 1999 7 29
8. M. Tucci, C. Quatraro, M.A. Frassanito, and F. Silvestris Deregulated expression of monocyte chemoattractant protein-1 (MCP-1) in arterial hypertension: role in endothelial inflammation and atheromasia J Hypertens 24 2006 1307 1318
9. M. Usui, K. Egashira, H. Tomita, M. Koyanagi, M. Katoh, H. Shimokawa, M. Takeya, T. Yoshimura, K. Matsushima, and A. Takeshita Important role of local angiotensin II activity mediated via type 1 receptor in the pathogenesis of cardiovascular inflammatory changes induced by chronic blockade of nitric oxide synthesis in rats Circulation 101 2000 305 310
10. K.K. Koh, J.Y. Ahn, S.H. Han, D.S. Kim, D.K. Jin, H.S. Kim, M.S. Shin, T.H. Ahn, I.S. Choi, and E.K. Shin Pleiotropic effects of angiotensin II receptor blocker in hypertensive patients J Am Coll Cardiol 42 2003 905 910
11. Y. Jiang, D.I. Beller, G. Frendl, and D.T. Graves Monocyte chemoattractant protein-1 regulates adhesion molecule expression and cytokine production in human monocytes J Immunol 148 1992 2423 2428
12. M. Hernandez-Presa, C. Bustos, M. Ortego, J. Tunon, G. Renedo, M. Ruiz Ortega, and J. Egido Angiotensin-converting enzyme inhibition prevent arterial nuclear factor-κB activation, monocyte chemoattractant protein-1 expression, and macrophage infiltration in a rabbit model of early accelerated atherosclerosis Circulation 95 1997 1532 1541
13. M. Ishibashi, K. Hiasa, Q. Zhao, S. Inoue, K. Ohtani, S. Kitamoto, M. Tsuchihashi, T. Sugaya, I.F. Charo, S. Kura, T. Tsuzuki, T. Ishibashi, A. Takeshita, and K. Egashira Critical role of monocyte chemoattractant protein-1 receptor CCR2 on monocytes in hypertension-induced vascular inflammation and remodeling Circ Res 14 2004 1203 1210
14. W. Ni, S. Kitamoto, M. Ishibashi, M. Usui, S. Inoue, K. Hiasa, Q. Zhao, K. Nishida, A. Takeshita, and K. Egashira Monocyte chemoattractant protein-1 is an essential inflammatory mediator in angiotensin II-induced progression of established atherosclerosis in hypercholesterolemic mice Arterioscler Thromb Vasc Biol 24 2004 534 539
15. Q. Dai, M. Xu, M. Yao, and B. Sun Angiotensin AT1 receptor antagonists exert anti-inflammatory effects in spontaneously hypertensive rats Br J Pharmacol 152 2007 1042 1048
16. D. Fliser, K. Buchholz, and H. Haller Antiinflammatory effects of angiotensin II subtype 1 receptor blockade in hypertensive patients with microinflammation Circulation 110 2004 1103 1107
17. F.L. Chen, Z.H. Yang, Y. Liu, L.X. Li, W.C. Liang, X.C. Wang, W.B. Zhou, Y.H. Yang, and R.M. Hu Berberine inhibits the expression of TNFalpha, MCP-1, and IL-6 in AcLDL-stimulated macrophages through PPARgamma pathway Endocrine 33 2008 331 337
18. M. Ishibashi, K. Egashira, K. Hiasa, S. Inoue, W. Ni, Q. Zhao, M. Usui, S. Kitamoto, T. Ichiki, and A. Takeshita Antiinflammatory and antiarteriosclerotic effects of pioglitazone Hypertension 40 2002 687 693
19. S. Cianchetti, A. Del Fiorentino, R. Colognato, R. Di Stefano, F. Franzoni, and R. Pedrinelli Anti-inflammatory and anti-oxidant properties of telmisartan in cultured human umbilical vein endothelial cells Atherosclerosis 198 2008 22 28
20. E. Kaschina, F. Schrader, M. Sommerfeld, U.R. Kemnitz, A. Grzesiak, M. Krikov, and T. Unger Telmisartan prevents aneurysm progression in the rat by inhibiting proteolysis, apoptosis and inflammation J Hypertens 26 2008 26312373
21. T. Nakamura, T. Inoue, T. Suzuki, Y. Kawagoe, Y. Ueda, H. Koide, and K. Node Comparison of renal and vascular protective effects between telmisartan and amlodipine in hypertensive patients with chronic kidney disease with mild renal insufficiency Hypertens Res 31 2008 841 850
22. K. Kappert, O. Tsuprykov, J. Kaufmann, J. Fritzsche, I. Ott, M. Goebel, I.N. Bahr, P.L. Haßle, R. Gust, E. Fleck, T. Unger, P. Stawowy, and U. Kintscher Chronic treatment with losartan results in sufficient serum levels of the metabolite EXP3179 for PPARγ activation Hypertension 54 2009 738 743
23. H. Ikejima, T. Imanishi, H. Tsujioka, A. Kuroi, K. Kobayashi, M. Shiomi, Y. Muragaki, S. Mochizuki, M. Goto, K. Yoshida, and T. Akasaka Effects of telmisartan, a unique angiotensin receptor blocker with selective peroxisome proliferator-activated receptor-gamma-modulating activity, on nitric oxide bioavailability and atherosclerotic change J Hypertens 26 2008 964 972
24. F. Pelliccia, V. Pasceri, C. Cianfrocca, C. Vitale, G. Speciale, C. Gaudio, G.M. Rosano, and G. Mercuro Angiotensin II receptor antagonism with telmisartan increases number of endothelial progenitor cells in normotensive patients with coronary artery disease: a randomized, double-blind, placebo-controlled study Atherosclerosis 210 2010 510 515
25. N. Ishii, T. Matsumura, H. Kinoshita, K. Fukuda, H. Motoshima, T. Senokuchi, S. Nakao, A. Tsutsumi, S. Kim-Mitsuyama, T. Kawada, M. Takeya, N. Miyamura, T. Nishikawa, and E. Araki Nifedipine induces peroxisome proliferator-activated receptor-gamma activation in macrophages and suppresses the progression of atherosclerosis in apolipoprotein E-deficient mice Arterioscler Thromb Vasc Biol 30 2010 1598 1605
26. J.L. Martin-Ventura, B. Muoz-Garcia, L.M. Blanco-Colio, A. Martn-Conejero, J. Madrigal-Matute, M. Vega, L. Ortega, J. Serrano, and J. Egido Treatment with amlodipine and atorvastatin has additive effect on blood and plaque inflammation in hypertensive patients with carotid atherosclerosis Kidney Int Suppl 111 2008 S71 S74
27. M. Ricote, J. Huang, L. Fajas, A. Li, J. Welch, J. Najib, J.L. Witztum, J. Auwerx, W. Palinski, and C.K. Glass Expression of the peroxisome proliferator-activated receptor-gamma (PPAR-gamma) in human atherosclerosis and regulation in macrophages by colony stimulating factors and oxidized low density lipoprotein Proc Natl Acad Sci U S A 95 1998 7614 7619
28. X. Xin, S. Yang, J. Kowalski, and M.E. Gerritsen Peroxisome proliferator-activated receptor-gamma ligands are potent inhibitors of angiogenesis in vitro and in vivo J Biol Chem 274 1999 9116 9121
29. R.E. Law, S. Goetze, X.P. Xi, S. Jackson, Y. Kawano, L. Demer, M.C. Fishbein, W.P. Meehan, and W.A. Hsueh Expression and function of PPAR-gamma in rat and human vascular smooth muscle cells Circulation 101 2000 1311 1318
30. U. Kintscher, S. Wakino, D. Bruemmer, S. Goetze, K. Graf, W.A. Hsueh, and R.E. Law TGF-beta(1) induces peroxisome proliferator-activated receptor gamma1 and gamma2 expression in human THP-1 monocytes Biochem Biophys Res Commun 297 2002 794 799
31. A. von Knethen, and B. Brune PPAR-gammaan important regulator of monocyte/macrophage function Arch Immunol Ther Exp 51 2003 219 226