Comparison between conventional surgery plus postoperative adjuvant radiotherapy and concurrent chemoradiation for FIGO stage IIB cervical carcinoma: A retrospective study

American Journal of Clinical Oncology: Cancer Clinical Trials

Volumn 33, Issue 6, 2010, Pages 583-586

  Yamashita, Hideomi ^a   Okuma, Kae ^a   Kawana, Kei ^b   Nakagawa, Shunsuke ^b   Oda, Katsutoshi ^b   Yano, Tetsu ^b   Kobayashi, Shino ^a   Wakui, Reiko ^a   Ohtomo, Kuni ^a   Nakagawa, Keiichi ^a  

^a Saonoda Medical Corporations   (Japan)

^b UNIVERSITY OF TOKYO HOSPITAL   (Japan)

Author keywords

Cervical carcinoma; Chemoradiotherapy; High doserate brachytherapy; Stage IIB; Surgery

Indexed keywords

CISPLATIN;

ADULT; AGED; ARTICLE; CANCER STAGING; CONTROLLED STUDY; EXTERNAL BEAM RADIOTHERAPY; FEMALE; FOLLOW UP; GROUPS BY AGE; HUMAN; HYPERTENSION; HYSTERECTOMY; INTERMETHOD COMPARISON; INTESTINE PERFORATION; LYMPH NODE DISSECTION; LYMPHANGITIS; LYMPHEDEMA; MAJOR CLINICAL STUDY; MELENA; OVERALL SURVIVAL; PROCTITIS; RADIATION DOSE; TREATMENT OUTCOME; UNSPECIFIED SIDE EFFECT; URINARY TRACT INFECTION; UTERINE CERVIX CARCINOMA;

ADULT; AGED; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CHEMOTHERAPY, ADJUVANT; CHI-SQUARE DISTRIBUTION; COHORT STUDIES; COMBINED MODALITY THERAPY; DISEASE-FREE SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DOSE-RESPONSE RELATIONSHIP, RADIATION; FEMALE; FOLLOW-UP STUDIES; HUMANS; HYSTERECTOMY; KAPLAN-MEIER ESTIMATE; MIDDLE AGED; NEOPLASM INVASIVENESS; NEOPLASM STAGING; RADIOTHERAPY, ADJUVANT; RETROSPECTIVE STUDIES; RISK ASSESSMENT; STATISTICS, NONPARAMETRIC; SURVIVAL ANALYSIS; TREATMENT OUTCOME; UTERINE CERVICAL NEOPLASMS;

EID: 78650035283     PISSN: 02773732     EISSN: 1537453X     Source Type: Journal    
DOI: 10.1097/COC.0b013e3181cae5b7     Document Type: Article

References (19)

1. Morita K. Cancer of the cervix. In: Vahrson HW, ed. Radiation Oncology of Gynecological Cancers. Berlin, Germany: Springer; 1997:143-239.
2. Eifel PJ. High-dose-rate brachytherapy for carcinoma of the cervix: high tech or high risk? Int J Radiat Oncol Biol Phys. 1992;24:383-386.
3. Eifel PJ, Moughan J, Owen J, et al. Patterns of radiotherapy practice for patients with squamous carcinoma of the uterine cervix: patterns of care study. Int J Radiat Oncol Biol Phys. 1999;43:351-348.
4. Nag S, Orton C, Young D, et al. The American brachytherapy society survey of brachytherapy practice for carcinoma of the cervix in the United States. Gynecol Oncol. 1999;73:111-118.
5. Rose PG, Bundy BN, Watkins EB, et al. Concurrent cisplatin-based chemotherapy and radiotherapy for locally advanced cervical cancer. N Engl J Med. 1999;340:1144-1153.
6. Whitney CW, Sause W, Bundy BN, et al. A randomized comparison of fluorouracil plus cisplatin versus hydroxyurea as an adjunct to radiation therapy in stages IIB-IVA carcinoma of the cervix with negative para-aortic lymph nodes: A Gynecologic Oncology Group and Southwest Oncology Group study. J Clin Oncol. 1999;17:1339-1348.
7. Morris M, Eifel PJ, Lu J, et al. Pelvic radiation with concurrent chemotherapy compared with pelvic and paraaortic radiation for high-risk cervical cancer. N Engl J Med. 1999;340:1137-1143.
8. Eifel PJ, Morris M, Wharton JT, et al. The influence of tumor size and morphology on the outcome of patients with FIGO stage IB squamous cell carcinoma of the uterine cervix. Int J Radiat Oncol Biol Phys. 1994;29:9-16.
9. Horiot JC, Pigneux J, Pourquier H, et al. Radiotherapy alone in carcinoma of the intact uterine cervix according to G. H. Fletcher guidelines: A French cooperative study of 1383 cases. Int J Radiat Oncol Biol Phys. 1988;14:605-611.
10. Liu W, Meigs JV. Radical hysterectomy and pelvic lymphadenectomy. A review of 473 cases including 244 for primary invasive carcinoma of the cervix. Am J Obstet Gynecol. 1955;69:1-32.
11. Newton M. Radical hysterectomy or radiotherapy for stage I cervical cancer. Am J Obstet Gynecol. 1975;123:535-542.
12. Tod MC, Meredith WJ. A dosage system for use in the treatment of cancer of the uterine cervix. Br J Radiol. 1938;11:809-824.
13. Yamashita H, Nakagawa K, Tago M, et al. Treatment results and prognostic analysis of radical radiotherapy for locally advanced cancer of the uterine cervix. Br J Radiol. 2005;78:821-826.
14. Yamashita H, Nakagawa K, Tago M, et al. Comparison between conventional surgery and radiotherapy for FIGO stage I-II cervical carcinoma: A retrospective Japanese study. Gynecol Oncol. 2005;97:834-839.
15. Morley GW, Seski JC. Radical pelvic surgery versus radiation therapy for stage I carcinoma of the cervix (exclusive of microinvasion). Am J Obstet Gynecol. 1976;126:785-798.
16. Landoni F, Maneo A, Colombo A, et al. Randomized study of radical surgery versus radiotherapy for stage Ib-IIa cervical cancer. Lancet. 1997;350:535-540.
17. Horn LC, Fischer U, Raptis G, et al. Tumor size is of prognostic value in surgically treated FIGO stage II cervical cancer. Gynecol Oncol. 2007;107: 310-315.
18. Rotman M, Sedlis A, Piedmonte MR, et al. A phase III randomized trial of postoperative pelvic irradiation in Stage IB cervical carcinoma with poor prognostic features: follow-up of a gynecologic oncology group study. Int J Radiat Oncol Biol Phys. 2006;65:169-176.
19. Perez CA, Grigsby PW, Chao KS, et al. Tumor size, irradiation dose, and long-term outcome of carcinoma of uterine cervix. Int J Radiat Oncol Biol Phys. 1998;41:307-317.