Comparison of conformal and intensity modulated radiation therapy techniques for treatment of pelvic tumors. Analysis of acute toxicity

Radiation Oncology

Volumn 5, Issue 1, 2010, Pages

  Ferrigno, Robson ^a   Santos, Adriana ^a   Martins, Lidiane C ^a   Weltman, Eduardo ^a   Chen, Michael J ^a   Sakuraba, Roberto ^a   Lopes, Cleverson P ^a   Cruz, José C ^a  

^a HOSPITAL ISRAELITA ALBERT EINSTEIN   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

ACUTE TOXICITY; ADULT; AGED; ARTICLE; CONTROLLED STUDY; DIARRHEA; FEMALE; GASTROINTESTINAL TOXICITY; HUMAN; INTENSITY MODULATED RADIATION THERAPY; INTERMETHOD COMPARISON; MAJOR CLINICAL STUDY; MALE; MORBIDITY; NEPHROTOXICITY; PELVIS LYMPH NODE; PELVIS TUMOR; PRIMARY TUMOR; RADIATION DOSE; CARCINOMA; COMPARATIVE STUDY; COMPUTER ASSISTED RADIOTHERAPY; EVALUATION; INCIDENCE; METHODOLOGY; MIDDLE AGED; PATHOLOGY; RADIATION INJURY; RETROSPECTIVE STUDY; TIME;

ADULT; AGED; AGED, 80 AND OVER; CARCINOMA; FEMALE; HUMANS; INCIDENCE; MALE; MIDDLE AGED; PELVIC NEOPLASMS; RADIATION INJURIES; RADIOTHERAPY, CONFORMAL; RADIOTHERAPY, INTENSITY-MODULATED; RETROSPECTIVE STUDIES; TIME FACTORS;

EID: 78650030235     PISSN: None     EISSN: 1748717X     Source Type: Journal    
DOI: 10.1186/1748-717X-5-117     Document Type: Article

References (31)

1. Perez CA, Breaux S, Bedwinek JM, et al. Radiation therapy alone in the treatment of carcinoma of the uterine cervix. II. Analysis of complications. Cancer 1984, 54:235-356. 10.1002/1097-0142(19840715)54:2<235::AID-CNCR2820540210>3.0.CO;2-H, 6722748.
2. Roeske JC, Mundt AJ, Halpern H, et al. Late rectal sequelae following definitive radiation therapy for carcinoma of the uterine cervix: A dosimetric analysis. Int J Radiat Oncol Biol Phys 1997, 37:351-358. 10.1016/S0360-3016(96)00490-7, 9069307.
3. Corn BW, Lanciano RM, Greven KM, et al. Impact of improved irradiation technique, age, and lymph node sampling on the severe complication rate of surgically staged endometrial cancer patients. A multivariate analysis. J Clin Oncol 1994, 12:510-515.
4. Snijders-Keiholz A, Griffioen G, Davelaar J, et al. Vitamin B12 malabsortion after irradiation for gynaecological tumors. Anticancer Res 1993, 13:1877-1881.
5. Urbano MTG, Henrys AJ, Adams EJ, et al. Intensity-modulated radiotherapy in patients with locally advanced rectal cancer reduces volume of bowel treated to high dose levels. Int J Radiat Oncol Biol Phys 2006, 65:907-916. 10.1016/j.ijrobp.2005.12.056, 16751073.
6. Roeske JC, Lujan A, Rotmensch J, et al. Intensity-modulated whole pelvic radiation therapy in patients with gynecologic malignancies. Int J Radiat Oncol Biol Phys 2000, 48:1613-1621. 10.1016/S0360-3016(00)00771-9, 11121668.
7. Ahamad A, D'Souza W, Salehpour M, et al. Intensity-modulated radiation therapy after hysterectomy: comparison with conventional treatment and sensitivity of the normal-tissue-sparing effect to margin size. Int J Radiat Oncol Biol Phys 2005, 62:1117-1124. 10.1016/j.ijrobp.2004.12.029, 15990017.
8. D'Souza WD, Ahamad AA, Iyer RB, et al. Feasibility of dose escalation using intensity-modulated radiotherapy in posthysterectomy cervical carcinoma. Int J Radiat Oncol Biol Phys 2005, 61:1062-1070.
9. Milano MT, Jani AB, Farrey KJ, et al. Intensity-modulated radiation therapy (IMRT) in the treatment of anal cancer: toxicity and clinical outcome. Int J Radiat Oncol Biol Phys 2005, 63:354-361. 10.1016/j.ijrobp.2005.02.030, 16168830.
10. Chan P, Yeo I, Perkins G, et al. Dosimetric comparison of intensity-modulated, conformal, and four-field pelvic radiotherapy boost plans for gynecologic cancer: a retrospective planning study. Radiat Oncol 2006, 4:13-21.
11. Engels B, De Ridder M, Tournel K, et al. Preoperative helical tomotherapy and megavoltage computed tomography for rectal cancer: impact on the irradiated volume of small bowel. Int J Radiat Oncol Biol Phys 2009, 74:1476-1480. 10.1016/j.ijrobp.2008.10.017, 19231097.
12. Sondergaard J, Hoyer M, Petersen JB, et al. The normal tissue sparing obtained with simultaneous treatment of pelvic lymph node and bladder using intensity-modulated radiotherapy. Int J Radiat Oncol Biol Phys 2009, 48:238-244.
13. Menkarios C, Azria D, Laliberté B, et al. Optimal organ-sparing intensity-modulated radiation therapy (IMRT) regimen for the treatment of locally advanced anal canal carcinoma: a comparison of conventional and IMRT plans. Radiat Oncol 2007, 15:41-49.
14. Mell LK, Tiryaki H, Ahn KH, et al. Dosimetric comparison of bone marrow-sparing intensity-modulated radiotherapy versus conventional techniques for treatment of cervical cancer. Int J Radiat Oncol Biol Phys 2008, 71:1504-1510. 10.1016/j.ijrobp.2008.04.046, 18640499.
15. Lujan AE, Mundt AJ, Yamada SD, et al. Intensity-modulated radiotherapy as a means of reducing dose to bone marrow in gynecologic patients receiving whole pelvic radiotherapy. Mell LK, Tiryaki H, Ahn KH, et al. Dosimetric comparison of bone marrow-sparing intensity-modulated radiotherapy versus conventional techniques for treatment of cervical cancer. Int J Radiat Oncol Biol Phys 2003, 57:516-521. 10.1016/S0360-3016(03)00521-2, 12957265.
16. Mundt AJ, Roeske JC, Lujan AE, et al. Initial clinical experience with intensity-modulated whole-pelvis radiation therapy in women with gynecologic malignancies. Gynecol Oncol 2001, 82:456-563. 10.1006/gyno.2001.6250, 11520140.
17. Mundt AJ, Lujan AE, Rotmensch J, et al. Intensity-modulated whole pelvic radiotherapy in women with gynecologic malignancies. Int J Radiat Oncol Biol Phys 2002, 52:1330-1337. 10.1016/S0360-3016(01)02785-7, 11955746.
18. Mundt AJ, Mell LK, Roeske JC. Preliminary analysis of chronic gastrointestinal toxicity in gynecologic patients treated with intensity-modulated whole pelvic radiation therapy. Int J Radiat Oncol Biol Phys 2003, 56:1354-1360. 10.1016/S0360-3016(03)00325-0, 12873680.
19. Beriwal S, Heron DE, Kim H, et al. Intensity-modulated radiotherapy for the treatment of vulvar carcinoma: a comparative dosimetric study with early clinical outcome. Int J Radiat Oncol Biol Phys 2006, 64:1395-1400. 10.1016/j.ijrobp.2005.11.007, 16442238.
20. Beriwal S, Jain S, Heron DE, et al. Clinical outcome with adjuvant treatment of endometrial carcinoma using intensity-modulated radiation therapy. Gynecol Oncol 2006, 102:195-199. 10.1016/j.ygyno.2006.01.062, 16647748.
21. Ballonoff A, Kavanagh B, McCarter M, et al. Preoperative capecitabine and accelerated intensity-modulated radiotherapy in locally advanced rectal cancer: a phase II trial. Am J Clin Oncol 2008, 31:264-270. 10.1097/COC.0b013e318161dbd3, 18525306.
22. Tierney RM, Powell MA, Mutch DG, et al. Acute toxicity of postoperative IMRT and chemotherapy for endometrial cancer. Radiat Med 2007, 25:439-445. 10.1007/s11604-007-0163-1, 18026901.
23. Chen MF, Tseng CJ, Kuo YC, et al. Clinical outcome in posthysterectomy cervical cancer patients treated with concurrent cisplatin and intensity-modulated pelvic radiotherapy: comparison with conventional radiotherapy. Int J Radiat Oncol Biol Phys 2007, 67:1438-1444. 10.1016/j.ijrobp.2006.11.005, 17394944.
24. Brixey CJ, Roeske JC, Lujan AE, et al. Impact of intensity-modulated radiotherapy on acute hematological toxicity in women with gynecologic malignancies. Int J Radiat Oncol Biol Phys 2002, 54:1388-1396. 10.1016/S0360-3016(02)03801-4, 12459361.
25. Mell LK, Kochanski JD, Roeske JC. Dosimetric predictors of acute hematologic toxicity in cervical cancer patients treated with concurrent cisplatin and intensity-modulated pelvic radiotherapy. Int J Radiat Oncol Biol Phys 2006, 66:1356-1365. 10.1016/j.ijrobp.2006.03.018, 16757127.
26. International Commission on Radiation Units and Measurements (ICRU) Report Number 50: Prescribing, recording, and reporting photon beam therapy. 1993, Washington, DC: ICRU, International Commission on Radiation Units and Measurements (ICRU).
27. Cox JF, Stetz J, Pajak TF. Toxicity criteria of the Radiation Therapy Oncology Group (RTOG) and the European Organization for Research and Treatment of Cancer (EORTC). Int J Radiat Oncol Biol Phys 1995, 31:1341-1346. 10.1016/0360-3016(95)00060-C, 7713792.
28. Ferrigno R, Santos A, Weltman E, et al. Elective radiotherapy with intensity modulated radiation therapy (IMRT) technique in the treatment of pelvic lymph nodes and primary tumor region. Analysis of acute toxicity. Procedings of the 49th ASTRO Annual Meeting 2009, Chicago, IL, Abstract number 1109.
29. Randall ME, Ibbott GS. Intensity-modulated radiation therapy for gynecologic cancers: Pitfall, hazards, and cautions to be considered. Semin Radiat Oncol 2006, 16:138-143. 10.1016/j.semradonc.2006.02.002, 16814153.
30. Jhingran A. Potential advantages of intensity-modulated radiation therapy in gynecologic malignancies. Semin Radiat Oncol 2006, 16:144-151. 10.1016/j.semradonc.2006.05.001, 16814154.
31. Veldeman L, Madani I, Hulstaert F, et al. Evidence behind use of intensity-modulated radiotherapy: a systematic review of comparative clinical studies. Lancet Oncol 2008, 9:367-375. 10.1016/S1470-2045(08)70098-6, 18374290.