Ectopic osteochondral formation of biomimetic porous PVA-n-HA/PA6 bilayered scaffold and BMSCs construct in rabbit

Journal of Biomedical Materials Research - Part B Applied Biomaterials

Volumn 96 B, Issue 1, 2011, Pages 9-15

  Qu, Dan ^a   Li, Jihua ^a   Li, Yubao ^b   Khadka, Ashish ^a   Zuo, Yi ^b   Wang, Hang ^a   Liu, Yiming ^a   Cheng, Lin ^b  

^a SICHUAN UNIVERSITY   (China)

^b SICHUAN UNIVERSITY   (China)

Author keywords

ectopic; osteochondral; poly vinyl alcohol gelatin(PVA) nano hydroxyapatite polyamide6 (PVA n HA PA6)

Indexed keywords

ARTICULAR CARTILAGES; BIOMIMETIC PROPERTIES; CARTILAGE REPAIR; CARTILAGINOUS TISSUES; CELLULAR PHENOTYPES; CHONDROGENIC; COLLAGEN TYPE I; ECTOPIC; ENGINEERED CARTILAGE; EXTRACELLULAR MATRICES; IN-VITRO; MESENCHYMAL STEM CELL; NEOCARTILAGE; OSTEOCHONDRAL; OSTEOGENIC POTENTIAL; POLY VINYL ALCOHOL/GELATIN(PVA)-NANO-HYDROXYAPATITE/POLYAMIDE6 (PVA-N-HA/PA6); POLYAMIDE 6; TYPE II;

BIOMIMETICS; BONE; CARTILAGE; CELL CULTURE; COLLAGEN; LIGAMENTS; STEM CELLS;

SCAFFOLDS;

BIOMIMETIC MATERIAL; COLLAGEN TYPE 2; POLY VINYL ALCOHOL GELATINNANO HYDROXYAPATITE POLYAMIDE6; TISSUE SCAFFOLD; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BONE CELL; BONE DEVELOPMENT; BONE MESENCHYMAL STEM CELL; CARTILAGE CELL; CHONDROGENESIS; EXTRACELLULAR MATRIX; IN VITRO STUDY; IN VIVO STUDY; MESENCHYMAL STEM CELL; NONHUMAN; OSTEOID; RABBIT; TISSUE ENGINEERING;

ANIMALS; ANTIGENS, DIFFERENTIATION; BIOMIMETIC MATERIALS; BONE SUBSTITUTES; CAPROLACTAM; CARTILAGE; COLLAGEN TYPE I; COLLAGEN TYPE II; DURAPATITE; FEMALE; GELATIN; GENE EXPRESSION REGULATION; MATERIALS TESTING; MESENCHYMAL STEM CELLS; POLYMERS; POLYVINYL ALCOHOL; RABBITS; TISSUE ENGINEERING; TISSUE SCAFFOLDS;

EID: 78650028242     PISSN: 15524973     EISSN: 15524981     Source Type: Journal    
DOI: 10.1002/jbm.b.31697     Document Type: Article

References (25)

1. Grayson WL, Chao PH, Marolt D, Kaplan DL, Vunjak-Novakovic G,. Engineering custom-designed osteochondral tissue grafts. Trends Biotechnol 2008; 26: 181-189.
2. Mano JF, Reis RL,. Osteochondral defects: Present situation and tissue engineering approaches. J Tissue Eng Regen Med 2007; 1: 261-273.
3. O'Shea TM, Miao X,. Bilayered scaffolds for osteochondral tissue engineering. Tissue Eng Part B Rev 2008; 14: 447-464.
4. Martin I, Miot S, Barbero A, Jakob M, Wendt D,. Osteochondral tissue engineering. J Biomech 2007; 40: 750-765.
5. Chang CH, Lin FH, Lin CC, Chou CH, Liu HC,. Cartilage tissue engineering on the surface of a novel gelatin-calcium-phosphate biphasic scaffold in a double-chamber bioreactor. J Biomed Mater Res B Appl Biomater 2004; 71: 313-321.
6. Filova E, Jelinek F, Handl M, Lytvynets A, Rampichova M, Varga F, Cinatl J, Soukup T, Trc T, Amler E,. Novel composite hyaluronan/type I collagen/fibrin scaffold enhances repair of osteochondral defect in rabbit knee. J Biomed Mater Res B Appl Biomater 2008; 87: 415-424.
7. Cao T, Ho KH, Teoh SH,. Scaffold design and in vitro study of osteochondral coculture in a three-dimensional porous polycaprolactone scaffold fabricated by fused deposition modeling. Tissue Eng 2003; 9: 103-112.
8. Ushio K, Oka M, Hyon SH, Hayami T, Yura S, Matsumura K, Toguchida J, Nakamura T,. Attachment of artificial cartilage to underlying bone. J Biomed Mater Res B Appl Biomater 2004; 68: 59-68.
9. Kitahara S, Nakagawa K, Sah RL, Wada Y, Ogawa T, Moriya H, Masuda K,. In vivo maturation of scaffold-free engineered articular cartilage on hydroxyapatite. Tissue Eng Part A 2008; 14: 1905-1913.
10. Vincent T, Hermansson M, Bolton M, Wait R, Saklatvala J,. Basic FGF mediates an immediate response of articular cartilage to mechanical injury. Proc Natl Acad Sci USA 2002; 99: 8259-8264.
11. Chung C, Burdick JA,. Engineering cartilage tissue. Adv Drug Deliv Rev 2008; 60: 243-262.
12. Bodugoz-Senturk H, Macias CE, Kung JH, Muratoglu OK,. Poly(vinyl alcohol)-acrylamide hydrogels as load-bearing cartilage substitute. Biomaterials 2009; 30: 589-596.
13. Cheng L, Li Y, Zuo Y, Li J, Wang H,. Nano-hydroxyapatite/polyamide 6 scaffold as potential tissue engineered bone substitutes. Mater Res Innov 2008; 12: 192-199.
14. Wang H, Li Y, Zuo Y, Li J, Sansi Ma S, Cheng L,. Biocompatibility and osteogenesis of biomimetic nano-hydroxyapatite/polyamide composite scaffolds for bone tissue engineering. Biomaterials 2007; 28: 3338-3348.
15. Pelttari K, Steck E, Richter W,. The use of mesenchymal stem cells for chondrogenesis. Injury 2008; 39: 58-65.
16. Csaki C, Schneider PR, Shakibaei M,. Mesenchymal stem cells as a potential pool for cartilage tissue engineering. Ann Anat 2008; 190: 395-412.
17. Cancedda R, Dozin B, Giannoni P, Quarto R,. Tissue engineering and cell therapy of cartilage and bone. Matrix Biol 2003; 22: 81-91. (Pubitemid 36444510)
18. Peppas NA, Simmons REP,. Mechanistic analysis of protein delivery from porous poly (vinyl alcohol) systems. J Drug Deliv Sci Technol 2004; 14: 285-289.
19. Tropel P, Noël D, Platet N, Legrand P, Benabid AL, Berger F,. Isolation and characterisation of mesenchymal stem cells from adult mouse bone marrow. Exp Cell Res 2004; 295: 395-406.
20. Barry FP, Murphy JM,. Mesenchymal stem cells: Clinical applications and biological characterization. Int J Biochem Cell Biol 2004; 36: 568-584.
21. Tuli R, Nandi S, Li WJ, Tuli S, Huang X, Manner PA, Laquerriere P, Noth U, Hall DJ, Tuan RS,. Human mesenchymal progenitor cell-based tissue engineering of a single-unit osteochondral construct. Tissue Eng 2004; 10: 1169-1179.
22. Schaefer D, Martin I, Shastri P, Padera RF, Langer R, Freed LE, Vunjak-Novakovic G,. In vitro generation of osteochondral composites. Biomaterials 2000; 21: 2599-2606.
23. Shao XX, Hutmacher DW, Ho ST, Goh JC, Lee EH,. Evaluation of a hybrid scaffold/cell construct in repair of high-load-bearing osteochondral defects in rabbits. Biomaterials 2006; 27: 1071-1080.
24. Kreklau B, Sittinger M, Mensing MB, Voigt C, Berger G, Burmester GR, Rahmanzadeh R'Gross U,. Tissue engineering of biphasic joint cartilage transplants. Biomaterials 1999; 20: 1743-1749. (Pubitemid 29393129)
25. Pal K, Banthia AK, Majumdar DK,. Biomedical evaluation of polyvinyl alcohol-gelatin esterified hydrogel for wound dressing. J Mater Sci Mater Med 2007; 18: 1889-1894. (Pubitemid 47224919)