Cytoprotective and anti-inflammatory effects of spinasterol via the induction of heme oxygenase-1 in murine hippocampal and microglial cell lines

International Immunopharmacology

Volumn 10, Issue 12, 2010, Pages 1587-1594

  Jeong, Gil Saeng ^a   Li, Bin ^a   Lee, Dong Sung ^a   Kim, Ki Hyun ^b   Lee, Il Kyun ^b   Lee, Kang Ro ^b   Kim, Youn Chul ^a  

^a Wonkwang University   (South Korea)

^b Sungkyunkwan University   (South Korea)

Author keywords

Anti inflammatory; Antioxidative; Extracellular signal regulated kinase (ERK); Heme oxygenase (HO) 1; Spinasterol

Indexed keywords

ALPHA SPINASTEROL; GLUTAMIC ACID; HEME OXYGENASE 1; INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE; NITRITE; PROSTAGLANDIN E2; REACTIVE OXYGEN METABOLITE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CELL ACTIVATION; CELL PROTECTION; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DRUG EFFICACY; DRUG STRUCTURE; ENZYME ACTIVATION; ENZYME INDUCTION; ENZYME REGULATION; HIPPOCAMPUS; MICROGLIA; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; UPREGULATION;

ANIMALS; ANTI-INFLAMMATORY AGENTS; BLOTTING, WESTERN; CELL CULTURE TECHNIQUES; CELL LINE; CELL SURVIVAL; CYTOPROTECTION; DINOPROSTONE; ENZYME INDUCTION; HEME OXYGENASE-1; HIPPOCAMPUS; INTERLEUKIN-1; MICE; MICROGLIA; MOLECULAR STRUCTURE; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; STIGMASTEROL; TUMOR NECROSIS FACTOR-ALPHA;

EID: 78650026009     PISSN: 15675769     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.intimp.2010.09.013     Document Type: Article

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