Efficient gene targeting by homologous recombination in rat embryonic stem cells

PLoS ONE

Volumn 5, Issue 12, 2010, Pages

  Meek, Stephen ^a   Buehr, Mia ^a   Sutherland, Linda ^a   Thomson, Alison ^a   Mullins, John J ^b   Smith, Andrew J ^c   Burdon, Tom ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

^c UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; DNA MODIFICATION; ELECTROPORATION; EMBRYO; EMBRYONIC STEM CELL; EXON; GENE CASSETTE; GENE LOCUS; GENE TARGETING; GENE VECTOR; GENETIC MANIPULATION; HOMOLOGOUS RECOMBINATION; INBRED STRAIN; MALE; NONHUMAN; OUTBRED STRAIN; POLYMERASE CHAIN REACTION; RAT; SOUTHERN BLOTTING; SPRAGUE DAWLEY RAT; ANIMAL; BIOLOGICAL MODEL; BLASTOCYST; CELL CULTURE; CYTOLOGY; FISCHER 344 RAT; GENETIC PROCEDURES; GENETIC RECOMBINATION; GENETICS; METHODOLOGY; SPECIES DIFFERENCE; TRANSGENIC ANIMAL;

ANIMALIA; RATTUS;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; BLASTOCYST; CELLS, CULTURED; EMBRYONIC STEM CELLS; GENE TARGETING; GENETIC TECHNIQUES; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; MALE; MODELS, GENETIC; RATS; RATS, INBRED F344; RATS, SPRAGUE-DAWLEY; RECOMBINATION, GENETIC; SPECIES SPECIFICITY;

EID: 78649974857     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0014225     Document Type: Article

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