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Volumn 5, Issue 12, 2010, Pages

Inactivation of the Ecs ABC transporter of Staphylococcus aureus attenuates virulence by altering composition and function of bacterial wall

Author keywords

[No Author keywords available]

Indexed keywords

ABC TRANSPORTER; ABC TRANSPORTER ECS; ADHESIN; ALPHA DEFENSIN; ANTIBIOTIC AGENT; BACTERIAL POLYSACCHARIDE; CHELERYTHRINE; LYSOSTAPHIN; PROTEIN A; SANGUINARINE; STAPHYLOKINASE; UNCLASSIFIED DRUG; BENZOPHENANTHRIDINE DERIVATIVE; ISOQUINOLINE DERIVATIVE;

EID: 78649956056     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0014209     Document Type: Article
Times cited : (19)

References (40)
  • 1
    • 61549113146 scopus 로고    scopus 로고
    • New trends in pharmacogenomic strategies against resistance development in microbial infections
    • Ohlsen K, Dandekar G, Schwarz R, Dandekar T (2008) New trends in pharmacogenomic strategies against resistance development in microbial infections. Pharmacogenomics 9: 1711-1723.
    • (2008) Pharmacogenomics , vol.9 , pp. 1711-1723
    • Ohlsen, K.1    Dandekar, G.2    Schwarz, R.3    Dandekar, T.4
  • 2
    • 44949249999 scopus 로고    scopus 로고
    • Structure, function, and evolution of bacterial ATP-binding cassette systems
    • Davidson AL, Dassa E, Orelle C, Chen J (2008) Structure, function, and evolution of bacterial ATP-binding cassette systems. Microbiol Mol Biol Rev 72: 317-364.
    • (2008) Microbiol Mol Biol Rev , vol.72 , pp. 317-364
    • Davidson, A.L.1    Dassa, E.2    Orelle, C.3    Chen, J.4
  • 4
    • 0027939182 scopus 로고
    • Vibrio cholerae iron transport systems: Roles of heme and siderophore iron transport in virulence and identification of a gene associated with multiple iron transport systems
    • Henderson DP, Payne SM (1994) Vibrio cholerae iron transport systems: roles of heme and siderophore iron transport in virulence and identification of a gene associated with multiple iron transport systems. Infect Immun 62: 5120-5125.
    • (1994) Infect Immun , vol.62 , pp. 5120-5125
    • Henderson, D.P.1    Payne, S.M.2
  • 5
    • 0343395846 scopus 로고    scopus 로고
    • ABC transporter-mediated uptake of iron, siderophores, heme and vitamin B12
    • Koster W (2001) ABC transporter-mediated uptake of iron, siderophores, heme and vitamin B12. Res Microbiol 152: 291-301.
    • (2001) Res Microbiol , vol.152 , pp. 291-301
    • Koster, W.1
  • 6
    • 0024064875 scopus 로고
    • Mutants of Bacillus subtilis defective in protein export
    • Kontinen VP, Sarvas M (1988) Mutants of Bacillus subtilis defective in protein export. J Gen Microbiol 134: 2333-2344.
    • (1988) J Gen Microbiol , vol.134 , pp. 2333-2344
    • Kontinen, V.P.1    Sarvas, M.2
  • 7
    • 0030031254 scopus 로고    scopus 로고
    • Molecular analysis of an operon in Bacillus subtilis encoding a novel ABC transporter with a role in exoprotein production, sporulation and competence
    • Leskelä S, Kontinen VP, Sarvas M (1996) Molecular analysis of an operon in Bacillus subtilis encoding a novel ABC transporter with a role in exoprotein production, sporulation and competence. Microbiology 142: 71-77.
    • (1996) Microbiology , vol.142 , pp. 71-77
    • Leskelä, S.1    Kontinen, V.P.2    Sarvas, M.3
  • 8
    • 0032956990 scopus 로고    scopus 로고
    • Ecs, an ABC transporter of Bacillus subtilis: Dual signal transduction functions affecting expression of secreted proteins as well as their secretion
    • Leskelä S, Wahlström E, Hyyryläinen HL, Jacobs M, Palva A, et al. (1999) Ecs, an ABC transporter of Bacillus subtilis: dual signal transduction functions affecting expression of secreted proteins as well as their secretion. Mol Microbiol 31: 533-543.
    • (1999) Mol Microbiol , vol.31 , pp. 533-543
    • Leskelä, S.1    Wahlström, E.2    Hyyryläinen, H.L.3    Jacobs, M.4    Palva, A.5
  • 9
    • 0036157412 scopus 로고    scopus 로고
    • ClpXP protease regulates the signal peptide cleavage of secretory preproteins in Bacillus subtilis with a mechanism distinct from that of the Ecs ABC transporter
    • Pummi T, Leskelä S, Wahlström E, Gerth U, Tjalsma H, et al. (2002) ClpXP protease regulates the signal peptide cleavage of secretory preproteins in Bacillus subtilis with a mechanism distinct from that of the Ecs ABC transporter. J Bacteriol 184: 1010-1018.
    • (2002) J Bacteriol , vol.184 , pp. 1010-1018
    • Pummi, T.1    Leskelä, S.2    Wahlström, E.3    Gerth, U.4    Tjalsma, H.5
  • 10
    • 2942575893 scopus 로고    scopus 로고
    • Genes involved in formation of structured multicellular communities by Bacillus subtilis
    • Branda SS, Gonzalez-Pastor JE, Dervyn E, Ehrlich SD, Losick R, et al. (2004) Genes involved in formation of structured multicellular communities by Bacillus subtilis. J Bacteriol 186: 3970-3979.
    • (2004) J Bacteriol , vol.186 , pp. 3970-3979
    • Branda, S.S.1    Gonzalez-Pastor, J.E.2    Dervyn, E.3    Ehrlich, S.D.4    Losick, R.5
  • 11
    • 51149117340 scopus 로고    scopus 로고
    • The Bacillus subtilis ABC transporter EcsAB influences intramembrane proteolysis through RasP
    • Heinrich J, Lunden T, Kontinen VP, Wiegert T (2008) The Bacillus subtilis ABC transporter EcsAB influences intramembrane proteolysis through RasP. Microbiology 154: 1989-1997.
    • (2008) Microbiology , vol.154 , pp. 1989-1997
    • Heinrich, J.1    Lunden, T.2    Kontinen, V.P.3    Wiegert, T.4
  • 12
    • 69249083586 scopus 로고    scopus 로고
    • Waves of resistance: Staphylococcus aureus in the antibiotic era
    • Chambers HF, Deleo FR (2009) Waves of resistance: Staphylococcus aureus in the antibiotic era. Nat Rev Microbiol 7: 629-641.
    • (2009) Nat Rev Microbiol , vol.7 , pp. 629-641
    • Chambers, H.F.1    Deleo, F.R.2
  • 13
    • 67349278834 scopus 로고    scopus 로고
    • Serious infections due to methicillinresistant Staphylococcus aureus: An evolving challenge for physicians
    • Falcone M, Serra P, Venditti M (2009) Serious infections due to methicillinresistant Staphylococcus aureus: an evolving challenge for physicians. Eur J Intern Med 20: 343-347.
    • (2009) Eur J Intern Med , vol.20 , pp. 343-347
    • Falcone, M.1    Serra, P.2    Venditti, M.3
  • 15
    • 37549035397 scopus 로고    scopus 로고
    • Genome sequence of Staphylococcus aureus strain Newman and comparative analysis of staphylococcal genomes: Polymorphism and evolution of two major pathogenicity islands
    • Baba T, Bae T, Schneewind O, Takeuchi F, Hiramatsu K (2008) Genome sequence of Staphylococcus aureus strain Newman and comparative analysis of staphylococcal genomes: polymorphism and evolution of two major pathogenicity islands. J Bacteriol 190: 300-310.
    • (2008) J Bacteriol , vol.190 , pp. 300-310
    • Baba, T.1    Bae, T.2    Schneewind, O.3    Takeuchi, F.4    Hiramatsu, K.5
  • 16
    • 0036271625 scopus 로고    scopus 로고
    • A genome-wide strategy for the identification of essential genes in Staphylococcus aureus
    • Forsyth RA, Haselbeck RJ, Ohlsen KL, Yamamoto RT, Xu H, et al. (2002) A genome-wide strategy for the identification of essential genes in Staphylococcus aureus. Mol Microbiol 43: 1387-1400.
    • (2002) Mol Microbiol , vol.43 , pp. 1387-1400
    • Forsyth, R.A.1    Haselbeck, R.J.2    Ohlsen, K.L.3    Yamamoto, R.T.4    Xu, H.5
  • 17
    • 67650074385 scopus 로고    scopus 로고
    • Subcellular localization of the Staphylococcus aureus heme iron transport components IsdA and IsdB
    • Pishchany G, Dickey SE, Skaar EP (2009) Subcellular localization of the Staphylococcus aureus heme iron transport components IsdA and IsdB. Infect Immun 77: 2624-2634.
    • (2009) Infect Immun , vol.77 , pp. 2624-2634
    • Pishchany, G.1    Dickey, S.E.2    Skaar, E.P.3
  • 18
    • 77949386274 scopus 로고    scopus 로고
    • Staphylococcal PknB as the first prokaryotic representative of the proline-directed kinases
    • Miller M, Donat S, Rakette S, Stehle T, Kouwen TR, et al. Staphylococcal PknB as the first prokaryotic representative of the proline-directed kinases. PLoS One 5: e9057.
    • PLoS One , vol.5
    • Miller, M.1    Donat, S.2    Rakette, S.3    Stehle, T.4    Kouwen, T.R.5
  • 19
    • 60749121183 scopus 로고    scopus 로고
    • Surface proteins that promote adherence of Staphylococcus aureus to human desquamated nasal epithelial cells
    • doi: 10.1186/1471-2180-1189-1122
    • Corrigan RM, Miajlovic H, Foster TJ (2009) Surface proteins that promote adherence of Staphylococcus aureus to human desquamated nasal epithelial cells. BMC Microbiol 9: 22. doi: 10.1186/1471-2180-1189-1122.
    • (2009) BMC Microbiol , vol.9 , pp. 22
    • Corrigan, R.M.1    Miajlovic, H.2    Foster, T.J.3
  • 20
    • 71749114166 scopus 로고    scopus 로고
    • Growth phase-dependent regulation of the global virulence regulator Rot in clinical isolates of Staphylococcus aureus
    • doi:10.1016/ j.ijmm.2009.1007.1003
    • Jelsbak L, Hemmingsen L, Donat S, Ohlsen K, Boye K, et al. (2009) Growth phase-dependent regulation of the global virulence regulator Rot in clinical isolates of Staphylococcus aureus. Int J Med Microbiol;doi:10.1016/ j.ijmm.2009.1007.1003.
    • (2009) Int J Med Microbiol
    • Jelsbak, L.1    Hemmingsen, L.2    Donat, S.3    Ohlsen, K.4    Boye, K.5
  • 21
    • 0036919576 scopus 로고    scopus 로고
    • Protein A is a virulence factor in Staphylococcus aureus arthritis and septic death
    • Palmqvist N, Foster T, Tarkowski A, Josefsson E (2002) Protein A is a virulence factor in Staphylococcus aureus arthritis and septic death. Microb Pathog 33: 239-249.
    • (2002) Microb Pathog , vol.33 , pp. 239-249
    • Palmqvist, N.1    Foster, T.2    Tarkowski, A.3    Josefsson, E.4
  • 22
    • 0023518575 scopus 로고
    • Virulence of protein Adeficient and alpha-toxin-deficient mutants of Staphylococcus aureus isolated by allele replacement
    • Patel AH, Nowlan P, Weavers ED, Foster T (1987) Virulence of protein Adeficient and alpha-toxin-deficient mutants of Staphylococcus aureus isolated by allele replacement. Infect Immun 55: 3103-3110.
    • (1987) Infect Immun , vol.55 , pp. 3103-3110
    • Patel, A.H.1    Nowlan, P.2    Weavers, E.D.3    Foster, T.4
  • 23
    • 0035168217 scopus 로고    scopus 로고
    • Involvement of staphylococcal protein A and cytoskeletal actin in Staphylococcus aureus invasion of cultured human oral epithelial cells
    • Jung KY, Cha JD, Lee SH, Woo WH, Lim DS, et al. (2001) Involvement of staphylococcal protein A and cytoskeletal actin in Staphylococcus aureus invasion of cultured human oral epithelial cells. J Med Microbiol 50: 35-41.
    • (2001) J Med Microbiol , vol.50 , pp. 35-41
    • Jung, K.Y.1    Cha, J.D.2    Lee, S.H.3    Woo, W.H.4    Lim, D.S.5
  • 25
    • 2942572788 scopus 로고    scopus 로고
    • Regulatory elements of the Staphylococcus aureus protein A (Spa) promoter
    • Gao J, Stewart GC (2004) Regulatory elements of the Staphylococcus aureus protein A (Spa) promoter. J Bacteriol 186: 3738-3748.
    • (2004) J Bacteriol , vol.186 , pp. 3738-3748
    • Gao, J.1    Stewart, G.C.2
  • 26
    • 56949084305 scopus 로고    scopus 로고
    • Mathematical modelling of the regulation of spa (protein A) transcription in Staphylococcus aureus
    • Gustafsson E, Karlsson S, Oscarsson J, Sogard P, Nilsson P, et al. (2009) Mathematical modelling of the regulation of spa (protein A) transcription in Staphylococcus aureus. Int J Med Microbiol 299: 65-74.
    • (2009) Int J Med Microbiol , vol.299 , pp. 65-74
    • Gustafsson, E.1    Karlsson, S.2    Oscarsson, J.3    Sogard, P.4    Nilsson, P.5
  • 27
    • 33749183115 scopus 로고    scopus 로고
    • Regulated intramembrane proteolysis of FtsL protein and the control of cell division in Bacillus subtilis
    • Bramkamp M, Weston L, Daniel RA, Errington J (2006) Regulated intramembrane proteolysis of FtsL protein and the control of cell division in Bacillus subtilis. Mol Microbiol 62: 580-591.
    • (2006) Mol Microbiol , vol.62 , pp. 580-591
    • Bramkamp, M.1    Weston, L.2    Daniel, R.A.3    Errington, J.4
  • 28
    • 3142683280 scopus 로고    scopus 로고
    • The Bacillus subtilis sigmaW anti-sigma factor RsiW is degraded by intramembrane proteolysis through YluC
    • Schobel S, Zellmeier S, Schumann W, Wiegert T (2004) The Bacillus subtilis sigmaW anti-sigma factor RsiW is degraded by intramembrane proteolysis through YluC. Mol Microbiol 52: 1091-1105.
    • (2004) Mol Microbiol , vol.52 , pp. 1091-1105
    • Schobel, S.1    Zellmeier, S.2    Schumann, W.3    Wiegert, T.4
  • 29
    • 0033569682 scopus 로고    scopus 로고
    • Defensins and host defense
    • Ganz T (1999) Defensins and host defense. Science 286: 420-421.
    • (1999) Science , vol.286 , pp. 420-421
    • Ganz, T.1
  • 30
    • 0024391711 scopus 로고
    • Interaction of human defensins with Escherichia coli. Mechanism of bactericidal activity
    • Lehrer RI, Barton A, Daher KA, Harwig SS, Ganz T, et al. (1989) Interaction of human defensins with Escherichia coli. Mechanism of bactericidal activity. J Clin Invest 84: 553-561.
    • (1989) J Clin Invest , vol.84 , pp. 553-561
    • Lehrer, R.I.1    Barton, A.2    Daher, K.A.3    Harwig, S.S.4    Ganz, T.5
  • 31
    • 0028061984 scopus 로고
    • Interactions between human defensins and lipid bilayers: Evidence for formation of multimeric pores
    • Wimley WC, Selsted ME, White SH (1994) Interactions between human defensins and lipid bilayers: evidence for formation of multimeric pores. Protein Sci 3: 1362-1373.
    • (1994) Protein Sci , vol.3 , pp. 1362-1373
    • Wimley, W.C.1    Selsted, M.E.2    White, S.H.3
  • 32
    • 0038228616 scopus 로고    scopus 로고
    • Bacillus subtilis CcdA-defective mutants are blocked in a late step of cytochrome c biogenesis
    • Schiott T, Throne-Holst M, Hederstedt L (1997) Bacillus subtilis CcdA-defective mutants are blocked in a late step of cytochrome c biogenesis. J Bacteriol 179: 4523-4529.
    • (1997) J Bacteriol , vol.179 , pp. 4523-4529
    • Schiott, T.1    Throne-Holst, M.2    Hederstedt, L.3
  • 33
    • 29144482705 scopus 로고    scopus 로고
    • Allelic replacement in Staphylococcus aureus with inducible counter-selection
    • Bae T, Schneewind O (2005) Allelic replacement in Staphylococcus aureus with inducible counter-selection. Plasmid 55: 58-63.
    • (2005) Plasmid , vol.55 , pp. 58-63
    • Bae, T.1    Schneewind, O.2
  • 34
    • 70349737935 scopus 로고    scopus 로고
    • Transcriptome analysis of the responses of Staphylococcus aureus to antimicrobial peptides and characterization of the roles of vraDE and vraSR in antimicrobial resistance
    • doi: 410.1186/1471-2164-1110-1429
    • Pietiäinen M, Francois P, Hyyryläinen HL, Tangomo M, Sass V, et al. (2009) Transcriptome analysis of the responses of Staphylococcus aureus to antimicrobial peptides and characterization of the roles of vraDE and vraSR in antimicrobial resistance. BMC Genomics 10: 429. doi: 410.1186/1471-2164-1110-1429.
    • (2009) BMC Genomics , vol.10 , pp. 429
    • Pietiäinen, M.1    Francois, P.2    Hyyryläinen, H.L.3    Tangomo, M.4    Sass, V.5
  • 35
    • 0026088721 scopus 로고
    • Suppression of autolysis and cell wall turnover in heterogeneous Tn551 mutants of a methicillin-resistant Staphylococcus aureus strain
    • de Jonge BL, de Lencastre H, Tomasz A (1991) Suppression of autolysis and cell wall turnover in heterogeneous Tn551 mutants of a methicillin-resistant Staphylococcus aureus strain. J Bacteriol 173: 1105-1110.
    • (1991) J Bacteriol , vol.173 , pp. 1105-1110
    • de Jonge, B.L.1    de Lencastre, H.2    Tomasz, A.3
  • 36
    • 33749005403 scopus 로고    scopus 로고
    • Staphylococcus aureus mutants with increased lysostaphin resistance
    • Grundling A, Missiakas DM, Schneewind O (2006) Staphylococcus aureus mutants with increased lysostaphin resistance. J Bacteriol 188: 6286-6297.
    • (2006) J Bacteriol , vol.188 , pp. 6286-6297
    • Grundling, A.1    Missiakas, D.M.2    Schneewind, O.3
  • 37
    • 0023739278 scopus 로고
    • Functional discrimination between interleukin 6 and interleukin 1
    • Helle M, Boeije L, Aarden LA (1988) Functional discrimination between interleukin 6 and interleukin 1. Eur J Immunol 18: 1535-1540.
    • (1988) Eur J Immunol , vol.18 , pp. 1535-1540
    • Helle, M.1    Boeije, L.2    Aarden, L.A.3
  • 38
    • 30744475750 scopus 로고    scopus 로고
    • Phenotype microarray profiling of Staphylococcus aureus menD and hemB mutants with the small-colony-variant phenotype
    • von Eiff C, McNamara P, Becker K, Bates D, Lei XH, et al. (2006) Phenotype microarray profiling of Staphylococcus aureus menD and hemB mutants with the small-colony-variant phenotype. Journal of Bacteriology 188: 687-693.
    • (2006) Journal of Bacteriology , vol.188 , pp. 687-693
    • von Eiff, C.1    McNamara, P.2    Becker, K.3    Bates, D.4    Lei, X.H.5
  • 39
    • 65549131633 scopus 로고    scopus 로고
    • CodY in Staphylococcus aureus: A regulatory link between metabolism and virulence gene expression
    • Pohl K, Francois P, Stenz L, Schlink F, Geiger T, et al. (2009) CodY in Staphylococcus aureus: a regulatory link between metabolism and virulence gene expression. J Bacteriol 191: 2953-2963.
    • (2009) J Bacteriol , vol.191 , pp. 2953-2963
    • Pohl, K.1    Francois, P.2    Stenz, L.3    Schlink, F.4    Geiger, T.5
  • 40
    • 3943113640 scopus 로고    scopus 로고
    • Using ANOVA to analyze microarray data
    • Churchill GA (2004) Using ANOVA to analyze microarray data. Biotechniques 37: 173-175.
    • (2004) Biotechniques , vol.37 , pp. 173-175
    • Churchill, G.A.1


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