메뉴 건너뛰기




Volumn 12, Issue 6, 2010, Pages 426-432

Mitochondrial dysfunction and oxidative damage to sarcomeric proteins

Author keywords

Contractile dysfunction; Diastolic dysfunction; Heart failure; Hypertension; Hypertrophy; Mitochondria; Myofibrils; ROS; Sarcomere

Indexed keywords

ALPHA ACTININ; CATALASE; GLUTATHIONE PEROXIDASE; MUSCLE PROTEIN; MYOSIN LIGHT CHAIN 2; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SUPEROXIDE DISMUTASE; TROPOMYOSIN; TROPONIN T;

EID: 78649908978     PISSN: 15226417     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11906-010-0149-8     Document Type: Review
Times cited : (49)

References (53)
  • 2
    • 3843094224 scopus 로고    scopus 로고
    • Diastolic Heart Failure - Abnormalities in Active Relaxation and Passive Stiffness of the Left Ventricle
    • DOI 10.1056/NEJMoa032566
    • MR Zile CF Baicu WH Gaasch 2004 Diastolic heart failure-abnormalities in active relaxation and passive stiffness of the left ventricle N Engl J Med 350 19 1953 1959 1:CAS:528:DC%2BD2cXjslehs7o%3D 10.1056/NEJMoa032566 15128895 (Pubitemid 38580198)
    • (2004) New England Journal of Medicine , vol.350 , Issue.19
    • Zile, M.R.1    Baicu, C.F.2    Gaasch, W.H.3
  • 3
    • 63849247206 scopus 로고    scopus 로고
    • Redox sensitive signaling pathways in cardiac remodeling, hypertrophy and failure
    • 1:CAS:528:DC%2BD1MXltlWntbs%3D 10.2741/3443 19273265
    • N Anilkumar A Sirker AM Shah 2009 Redox sensitive signaling pathways in cardiac remodeling, hypertrophy and failure Front Biosci 14 3168 3187 1:CAS:528:DC%2BD1MXltlWntbs%3D 10.2741/3443 19273265
    • (2009) Front Biosci , vol.14 , pp. 3168-3187
    • Anilkumar, N.1    Sirker, A.2    Shah, A.M.3
  • 4
    • 33745193908 scopus 로고    scopus 로고
    • Redox signaling in hypertension
    • 1:CAS:528:DC%2BD28Xmt1ygs7o%3D 10.1016/j.cardiores.2006.05.001 16765337
    • TM Paravicini RM Touyz 2006 Redox signaling in hypertension Cardiovasc Res 71 2 247 258 1:CAS:528:DC%2BD28Xmt1ygs7o%3D 10.1016/j.cardiores.2006.05.001 16765337
    • (2006) Cardiovasc Res , vol.71 , Issue.2 , pp. 247-258
    • Paravicini, T.M.1    Touyz, R.M.2
  • 5
    • 0037785315 scopus 로고    scopus 로고
    • NADPH oxidase-derived superoxide anion mediates angiotensin II-induced cardiac hypertrophy
    • DOI 10.1016/S0022-2828(03)00145-7
    • H Nakagami M Takemoto JK Liao 2003 NADPH oxidase-derived superoxide anion mediates angiotensin II-induced cardiac hypertrophy J Mol Cell Cardiol 35 7 851 859 1:CAS:528:DC%2BD3sXks1artLo%3D 10.1016/S0022-2828(03)00145-7 12818576 (Pubitemid 36773597)
    • (2003) Journal of Molecular and Cellular Cardiology , vol.35 , Issue.7 , pp. 851-859
    • Nakagami, H.1    Takemoto, M.2    Liao, J.K.3
  • 6
    • 0036083322 scopus 로고    scopus 로고
    • Role of reactive oxygen species and NAD(P)H oxidase in alpha(1)-adrenoceptor signaling in adult rat cardiac myocytes
    • 1:CAS:528:DC%2BD38XivVemu7w%3D 11880281
    • L Xiao DR Pimentel J Wang, et al. 2002 Role of reactive oxygen species and NAD(P)H oxidase in alpha(1)-adrenoceptor signaling in adult rat cardiac myocytes Am J Physiol Cell Physiol 282 4 C926 C934 1:CAS:528: DC%2BD38XivVemu7w%3D 11880281
    • (2002) Am J Physiol Cell Physiol , vol.282 , Issue.4
    • Xiao, L.1    Pimentel, D.R.2    Wang, J.3
  • 7
    • 0035980171 scopus 로고    scopus 로고
    • Reactive oxygen species mediate amplitude-dependent hypertrophic and apoptotic responses to mechanical stretch in cardiac myocytes
    • 1:CAS:528:DC%2BD3MXmvFSrtL0%3D 10.1161/hh1701.096615 11532907
    • DR Pimentel JK Amin L Xiao, et al. 2001 Reactive oxygen species mediate amplitude-dependent hypertrophic and apoptotic responses to mechanical stretch in cardiac myocytes Circ Res 89 5 453 460 1:CAS:528:DC%2BD3MXmvFSrtL0%3D 10.1161/hh1701.096615 11532907
    • (2001) Circ Res , vol.89 , Issue.5 , pp. 453-460
    • Pimentel, D.R.1    Amin, J.K.2    Xiao, L.3
  • 9
    • 67449142998 scopus 로고    scopus 로고
    • Long-term administration of nifedipine attenuates cardiac remodeling and diastolic heart failure in hypertensive rats
    • 1:CAS:528:DC%2BD1MXnslyksL0%3D 10.1016/j.ejphar.2009.05.028 19501083
    • T Yamada K Nagata XW Cheng, et al. 2009 Long-term administration of nifedipine attenuates cardiac remodeling and diastolic heart failure in hypertensive rats Eur J Pharmacol 615 1-3 163 170 1:CAS:528:DC%2BD1MXnslyksL0%3D 10.1016/j.ejphar.2009.05.028 19501083
    • (2009) Eur J Pharmacol , vol.615 , Issue.13 , pp. 163-170
    • Yamada, T.1    Nagata, K.2    Cheng, X.W.3
  • 10
    • 77952364346 scopus 로고    scopus 로고
    • Decreased rates of substrate oxidation ex vivo predict the onset of heart failure and contractile dysfunction in rats with pressure overload
    • 1:CAS:528:DC%2BC3cXmtFKqtL4%3D 10.1093/cvr/cvp414 20035032 This study characterizes mitochondrial metabolic defects in a pressure-overload rat model of hypertrophy. Importantly, though impairment in fatty acid and glucose metabolism occurred early after transverse aortic constriction (TAC), mitochondrial respiratory capacity was preserved until 10 weeks after TAC, and its decrease correlated with impairment of ejection fraction
    • T Doenst G Pytel A Schrepper, et al. 2010 Decreased rates of substrate oxidation ex vivo predict the onset of heart failure and contractile dysfunction in rats with pressure overload Cardiovasc Res 86 3 461 470 1:CAS:528: DC%2BC3cXmtFKqtL4%3D 10.1093/cvr/cvp414 20035032 This study characterizes mitochondrial metabolic defects in a pressure-overload rat model of hypertrophy. Importantly, though impairment in fatty acid and glucose metabolism occurred early after transverse aortic constriction (TAC), mitochondrial respiratory capacity was preserved until 10 weeks after TAC, and its decrease correlated with impairment of ejection fraction
    • (2010) Cardiovasc Res , vol.86 , Issue.3 , pp. 461-470
    • Doenst, T.1    Pytel, G.2    Schrepper, A.3
  • 11
    • 70449486143 scopus 로고    scopus 로고
    • Additive beneficial effects of amlodipine and atorvastatin in reversing advanced cardiac hypertrophy in elderly spontaneously hypertensive rats
    • 1:CAS:528:DC%2BD1MXhsFKlt7jJ 10.1111/j.1440-1681.2009.05198.x 19413592
    • JC Lu W Cui HL Zhang, et al. 2009 Additive beneficial effects of amlodipine and atorvastatin in reversing advanced cardiac hypertrophy in elderly spontaneously hypertensive rats Clin Exp Pharmacol Physiol 36 11 1110 1119 1:CAS:528:DC%2BD1MXhsFKlt7jJ 10.1111/j.1440-1681.2009.05198.x 19413592
    • (2009) Clin Exp Pharmacol Physiol , vol.36 , Issue.11 , pp. 1110-1119
    • Lu, J.C.1    Cui, W.2    Zhang, H.L.3
  • 12
    • 0033695425 scopus 로고    scopus 로고
    • Plasma hydrogen peroxide production in human essential hypertension: Role of heredity, gender, and ethnicity
    • 1:CAS:528:DC%2BD3cXptVSitb4%3D 11082160
    • F Lacy MT Kailasam DT O'Connor, et al. 2000 Plasma hydrogen peroxide production in human essential hypertension: role of heredity, gender, and ethnicity Hypertension 36 5 878 884 1:CAS:528:DC%2BD3cXptVSitb4%3D 11082160
    • (2000) Hypertension , vol.36 , Issue.5 , pp. 878-884
    • Lacy, F.1    Kailasam, M.T.2    O'Connor, D.T.3
  • 13
    • 0033933231 scopus 로고    scopus 로고
    • Decreased endogenous antioxidant enzymatic status in essential hypertension
    • 1:CAS:528:DC%2BD3cXksVCgsbw%3D 10.1038/sj.jhh.1001034 10878691
    • J Pedro-Botet MI Covas S Martin J Rubies-Prat 2000 Decreased endogenous antioxidant enzymatic status in essential hypertension J Hum Hypertens 14 6 343 345 1:CAS:528:DC%2BD3cXksVCgsbw%3D 10.1038/sj.jhh.1001034 10878691
    • (2000) J Hum Hypertens , vol.14 , Issue.6 , pp. 343-345
    • Pedro-Botet, J.1    Covas, M.I.2    Martin, S.3    Rubies-Prat, J.4
  • 14
    • 35548939066 scopus 로고    scopus 로고
    • Involvement of NADPH oxidases in cardiac remodelling and heart failure
    • DOI 10.1159/000109148
    • A Sirker M Zhang C Murdoch AM Shah 2007 Involvement of NADPH oxidases in cardiac remodelling and heart failure Am J Nephrol 27 6 649 660 1:CAS:528:DC%2BD2sXht1Wgt7fK 10.1159/000109148 17901689 (Pubitemid 350014953)
    • (2007) American Journal of Nephrology , vol.27 , Issue.6 , pp. 649-660
    • Sirker, A.1    Zhang, M.2    Murdoch, C.3    Shah, A.M.4
  • 15
    • 0037154308 scopus 로고    scopus 로고
    • phox-containing NADPH oxidase in angiotensin II-induced cardiac hypertrophy in mice
    • DOI 10.1161/hc0302.103712
    • JK Bendall AC Cave C Heymes, et al. 2002 Pivotal role of a gp91(phox)-containing NADPH oxidase in angiotensin II-induced cardiac hypertrophy in mice Circulation 105 3 293 296 1:CAS:528:DC%2BD38XhsFSgtL4%3D 10.1161/hc0302.103712 11804982 (Pubitemid 34106175)
    • (2002) Circulation , vol.105 , Issue.3 , pp. 293-296
    • Bendall, J.K.1    Cave, A.C.2    Heymes, C.3    Gall, N.4    Shah, A.M.5
  • 16
    • 0242298634 scopus 로고    scopus 로고
    • Contrasting Roles of NADPH Oxidase Isoforms in Pressure-Overload Versus Angiotensin II-Induced Cardiac Hypertrophy
    • DOI 10.1161/01.RES.0000099504.30207.F5
    • JA Byrne DJ Grieve JK Bendall, et al. 2003 Contrasting roles of NADPH oxidase isoforms in pressure-overload versus angiotensin II-induced cardiac hypertrophy Circ Res 93 9 802 805 1:CAS:528:DC%2BD3sXotlejs70%3D 10.1161/01.RES.0000099504.30207.F5 14551238 (Pubitemid 37363053)
    • (2003) Circulation Research , vol.93 , Issue.9 , pp. 802-804
    • Byrne, J.A.1    Grieve, D.J.2    Bendall, J.K.3    Li, J.-M.4    Gove, C.5    Lambeth, J.D.6    Cave, A.C.7    Shah, A.M.8
  • 17
    • 77953722261 scopus 로고    scopus 로고
    • Delayed treatment effects of xanthine oxidase inhibition on systolic overload-induced left ventricular hypertrophy and dysfunction
    • 1:CAS:528:DC%2BC3cXnt1ymsbY%3D 10.1080/15257771003738683 20544512
    • X Xu L Zhao X Hu, et al. 2010 Delayed treatment effects of xanthine oxidase inhibition on systolic overload-induced left ventricular hypertrophy and dysfunction Nucleosides Nucleotides Nucleic Acids 29 4-6 306 313 1:CAS:528:DC%2BC3cXnt1ymsbY%3D 10.1080/15257771003738683 20544512
    • (2010) Nucleosides Nucleotides Nucleic Acids , vol.29 , Issue.46 , pp. 306-313
    • Xu, X.1    Zhao, L.2    Hu, X.3
  • 18
    • 0033588198 scopus 로고    scopus 로고
    • Mitochondrial electron transport complex i is a potential source of oxygen free radicals in the failing myocardium
    • 1:CAS:528:DyaK1MXltlehurg%3D 10455064
    • T Ide H Tsutsui S Kinugawa, et al. 1999 Mitochondrial electron transport complex I is a potential source of oxygen free radicals in the failing myocardium Circ Res 85 4 357 363 1:CAS:528:DyaK1MXltlehurg%3D 10455064
    • (1999) Circ Res , vol.85 , Issue.4 , pp. 357-363
    • Ide, T.1    Tsutsui, H.2    Kinugawa, S.3
  • 19
    • 34547828784 scopus 로고    scopus 로고
    • Right-ventricular failure is associated with increased mitochondrial complex II activity and production of reactive oxygen species
    • DOI 10.1016/j.cardiores.2007.05.012, PII S0008636307002416
    • EM Redout MJ Wagner MJ Zuidwijk, et al. 2007 Right-ventricular failure is associated with increased mitochondrial complex II activity and production of reactive oxygen species Cardiovasc Res 75 4 770 781 1:CAS:528: DC%2BD2sXpt1Srsr8%3D 10.1016/j.cardiores.2007.05.012 17582388 (Pubitemid 47243719)
    • (2007) Cardiovascular Research , vol.75 , Issue.4 , pp. 770-781
    • Redout, E.M.1    Wagner, M.J.2    Zuidwijk, M.J.3    Boer, C.4    Musters, R.J.P.5    Van Hardeveld, C.6    Paulus, W.J.7    Simonides, W.S.8
  • 20
    • 33645456962 scopus 로고    scopus 로고
    • Decline of contractility during ischemia-reperfusion injury: Actin glutathionylation and its effect on allosteric interaction with tropomyosin
    • 1:CAS:528:DC%2BD28Xjt1Sltbw%3D 10.1152/ajpcell.00419.2005 16251471
    • FC Chen O Ogut 2006 Decline of contractility during ischemia-reperfusion injury: actin glutathionylation and its effect on allosteric interaction with tropomyosin Am J Physiol Cell Physiol 290 3 C719 C727 1:CAS:528: DC%2BD28Xjt1Sltbw%3D 10.1152/ajpcell.00419.2005 16251471
    • (2006) Am J Physiol Cell Physiol , vol.290 , Issue.3
    • Chen, F.C.1    Ogut, O.2
  • 21
    • 37849040918 scopus 로고    scopus 로고
    • Free radicals and muscle fatigue: Of ROS, canaries, and the IOC
    • 1:CAS:528:DC%2BD1cXlvVygtQ%3D%3D 10.1016/j.freeradbiomed.2007.03.002 18191753
    • MB Reid 2008 Free radicals and muscle fatigue: Of ROS, canaries, and the IOC Free Radic Biol Med 44 2 169 179 1:CAS:528:DC%2BD1cXlvVygtQ%3D%3D 10.1016/j.freeradbiomed.2007.03.002 18191753
    • (2008) Free Radic Biol Med , vol.44 , Issue.2 , pp. 169-179
    • Reid, M.B.1
  • 22
    • 39949083028 scopus 로고    scopus 로고
    • The role of mitochondria in aging of skeletal muscle
    • 1:CAS:528:DC%2BD1cXitlyrsLo%3D 10.1007/s10522-007-9121-7 18175203
    • PA Figueiredo MP Mota HJ Appell JA Duarte 2008 The role of mitochondria in aging of skeletal muscle Biogerontology 9 2 67 84 1:CAS:528: DC%2BD1cXitlyrsLo%3D 10.1007/s10522-007-9121-7 18175203
    • (2008) Biogerontology , vol.9 , Issue.2 , pp. 67-84
    • Figueiredo, P.A.1    Mota, M.P.2    Appell, H.J.3    Duarte, J.A.4
  • 23
    • 68549112975 scopus 로고    scopus 로고
    • Mitochondria-targeted antioxidant MitoQ10 improves endothelial function and attenuates cardiac hypertrophy
    • 1:CAS:528:DC%2BD1MXosFWiu78%3D 10.1161/HYPERTENSIONAHA.109.130351 19581509
    • D Graham NN Huynh CA Hamilton, et al. 2009 Mitochondria-targeted antioxidant MitoQ10 improves endothelial function and attenuates cardiac hypertrophy Hypertension 54 2 322 328 1:CAS:528:DC%2BD1MXosFWiu78%3D 10.1161/HYPERTENSIONAHA.109.130351 19581509
    • (2009) Hypertension , vol.54 , Issue.2 , pp. 322-328
    • Graham, D.1    Huynh, N.N.2    Hamilton, C.A.3
  • 24
    • 70349481328 scopus 로고    scopus 로고
    • Possible involvement of mitochondrial energy-producing ability in the development of right ventricular failure in monocrotaline-induced pulmonary hypertensive rats
    • 1:CAS:528:DC%2BD1MXht1ert7vL 10.1254/jphs.08322FP 19763046
    • T Daicho T Yagi Y Abe, et al. 2009 Possible involvement of mitochondrial energy-producing ability in the development of right ventricular failure in monocrotaline-induced pulmonary hypertensive rats J Pharmacol Sci 111 1 33 43 1:CAS:528:DC%2BD1MXht1ert7vL 10.1254/jphs.08322FP 19763046
    • (2009) J Pharmacol Sci , vol.111 , Issue.1 , pp. 33-43
    • Daicho, T.1    Yagi, T.2    Abe, Y.3
  • 25
    • 77749291756 scopus 로고    scopus 로고
    • Antioxidant treatment attenuates pulmonary arterial hypertension-induced heart failure
    • 1:CAS:528:DC%2BC3cXjsFGns7k%3D 10.1152/ajpheart.00097.2009 20061549 Monocrotaline-induced RV heart failure in rats was successfully reversed with antioxidant EUK-134 administration. This superoxide dismutase and catalase mimetic targets both mitochondrial and cytosolic ROS and represents a potential therapeutic agent for treatment of RV dysfunction in pulmonary arterial hypertension.
    • EM Redout A van der Toorn MJ Zuidwijk, et al. 2010 Antioxidant treatment attenuates pulmonary arterial hypertension-induced heart failure Am J Physiol Heart Circ Physiol 298 3 H1038 H1047 1:CAS:528:DC%2BC3cXjsFGns7k%3D 10.1152/ajpheart.00097.2009 20061549 Monocrotaline-induced RV heart failure in rats was successfully reversed with antioxidant EUK-134 administration. This superoxide dismutase and catalase mimetic targets both mitochondrial and cytosolic ROS and represents a potential therapeutic agent for treatment of RV dysfunction in pulmonary arterial hypertension.
    • (2010) Am J Physiol Heart Circ Physiol , vol.298 , Issue.3
    • Redout, E.M.1    Van Der Toorn, A.2    Zuidwijk, M.J.3
  • 26
    • 78049434938 scopus 로고    scopus 로고
    • Age-dependent cardiomyopathy in mitochondrial mutator mice is attenuated by overexpression of catalase targeted to mitochondria
    • m/m mice, which overexpress the mitochondria-targeted antioxidant enzyme catalase. This study supports the importance of mitochondrial ROS in the development of cardiac dysfunction and provides evidence for the therapeutic potential of mitochondria-targeted antioxidants.
    • m/m mice, which overexpress the mitochondria-targeted antioxidant enzyme catalase. This study supports the importance of mitochondrial ROS in the development of cardiac dysfunction and provides evidence for the therapeutic potential of mitochondria-targeted antioxidants.
    • (2010) Aging Cell , vol.9 , Issue.4 , pp. 536-544
    • Dai, D.F.1    Chen, T.2    Wanagat, J.3
  • 27
    • 66249089511 scopus 로고    scopus 로고
    • Different extent of cardiac malfunction and resistance to oxidative stress in heterozygous and homozygous manganese-dependent superoxide dismutase-mutant mice
    • 1:CAS:528:DC%2BD1MXmtFSjt7s%3D 19293248 Mice with inducible heterozygous deletion of SOD2, a mitochondrial antioxidant, develop cardiac hypertrophy, systolic dysfunction, and increased fibrosis. This study supports the hypothesis that increased mitochondrial ROS production is sufficient to induce cardiomyopathy
    • T Loch O Vakhrusheva I Piotrowska, et al. 2009 Different extent of cardiac malfunction and resistance to oxidative stress in heterozygous and homozygous manganese-dependent superoxide dismutase-mutant mice Cardiovasc Res 82 3 448 457 1:CAS:528:DC%2BD1MXmtFSjt7s%3D 19293248 Mice with inducible heterozygous deletion of SOD2, a mitochondrial antioxidant, develop cardiac hypertrophy, systolic dysfunction, and increased fibrosis. This study supports the hypothesis that increased mitochondrial ROS production is sufficient to induce cardiomyopathy
    • (2009) Cardiovasc Res , vol.82 , Issue.3 , pp. 448-457
    • Loch, T.1    Vakhrusheva, O.2    Piotrowska, I.3
  • 28
    • 67649861056 scopus 로고    scopus 로고
    • Transgenic mitochondrial superoxide dismutase and mitochondrially targeted catalase prevent antiretroviral-induced oxidative stress and cardiomyopathy
    • 1:CAS:528:DC%2BD1MXnslKgsrc%3D 10.1038/labinvest.2009.39 19398959
    • JJ Kohler I Cucoranu E Fields, et al. 2009 Transgenic mitochondrial superoxide dismutase and mitochondrially targeted catalase prevent antiretroviral-induced oxidative stress and cardiomyopathy Lab Invest 89 7 782 790 1:CAS:528:DC%2BD1MXnslKgsrc%3D 10.1038/labinvest.2009.39 19398959
    • (2009) Lab Invest , vol.89 , Issue.7 , pp. 782-790
    • Kohler, J.J.1    Cucoranu, I.2    Fields, E.3
  • 29
    • 41749094096 scopus 로고    scopus 로고
    • Genetic determinants of cardiac hypertrophy
    • DOI 10.1097/HCO.0b013e3282fc27d9, PII 0000157320080500000006
    • AJ Marian 2008 Genetic determinants of cardiac hypertrophy Curr Opin Cardiol 23 3 199 205 10.1097/HCO.0b013e3282fc27d9 18382207 (Pubitemid 351489322)
    • (2008) Current Opinion in Cardiology , vol.23 , Issue.3 , pp. 199-205
    • Marian, A.J.1
  • 30
    • 0028860791 scopus 로고
    • Reduced contraction and altered frequency response of isolated ventricular myocytes from patients with heart failure
    • 1:STN:280:DyaK28%2FmvFaktg%3D%3D 7586355
    • CH Davies K Davia JG Bennett, et al. 1995 Reduced contraction and altered frequency response of isolated ventricular myocytes from patients with heart failure Circulation 92 9 2540 2549 1:STN:280:DyaK28%2FmvFaktg%3D%3D 7586355
    • (1995) Circulation , vol.92 , Issue.9 , pp. 2540-2549
    • Davies, C.H.1    Davia, K.2    Bennett, J.G.3
  • 32
    • 77951623501 scopus 로고    scopus 로고
    • Investigations into tropomyosin function using mouse models
    • 1:CAS:528:DC%2BC3cXksFCrsLk%3D 10.1016/j.yjmcc.2009.10.003 19835881
    • G Jagatheesan S Rajan DF Wieczorek 2010 Investigations into tropomyosin function using mouse models J Mol Cell Cardiol 48 5 893 898 1:CAS:528: DC%2BC3cXksFCrsLk%3D 10.1016/j.yjmcc.2009.10.003 19835881
    • (2010) J Mol Cell Cardiol , vol.48 , Issue.5 , pp. 893-898
    • Jagatheesan, G.1    Rajan, S.2    Wieczorek, D.F.3
  • 33
    • 33845778948 scopus 로고    scopus 로고
    • Troponin phosphorylation and regulatory function in human heart muscle: Dephosphorylation of Ser23/24 on troponin I could account for the contractile defect in end-stage heart failure
    • DOI 10.1016/j.yjmcc.2006.08.017, PII S0022282806007760
    • AE Messer AM Jacques SB Marston 2007 Troponin phosphorylation and regulatory function in human heart muscle: dephosphorylation of Ser23/24 on troponin I could account for the contractile defect in end-stage heart failure J Mol Cell Cardiol 42 1 247 259 1:CAS:528:DC%2BD2sXht1Cltw%3D%3D 10.1016/j.yjmcc.2006.08.017 17081561 (Pubitemid 44970468)
    • (2007) Journal of Molecular and Cellular Cardiology , vol.42 , Issue.1 , pp. 247-259
    • Messer, A.E.1    Jacques, A.M.2    Marston, S.B.3
  • 35
    • 75149149380 scopus 로고    scopus 로고
    • Protein carbonylation in skeletal muscles: Impact on function
    • 1:CAS:528:DC%2BC3cXitVahsb8%3D 10.1089/ars.2009.2808 19686036
    • E Barreiro SN Hussain 2010 Protein carbonylation in skeletal muscles: impact on function Antioxid Redox Signal 12 3 417 429 1:CAS:528: DC%2BC3cXitVahsb8%3D 10.1089/ars.2009.2808 19686036
    • (2010) Antioxid Redox Signal , vol.12 , Issue.3 , pp. 417-429
    • Barreiro, E.1    Hussain, S.N.2
  • 36
    • 77952021866 scopus 로고    scopus 로고
    • Identification, quantification, and functional aspects of skeletal muscle protein-carbonylation in vivo during acute oxidative stress
    • 1:CAS:528:DC%2BC3cXkvFaqt7Y%3D 10.1021/pr901182r 20377239 A series of recent papers from this group used an x-ray irradiation model of acute ROS production to study the dynamics and functional consequences of oxidative damage to sarcomeric proteins. Importantly, they found myofibrillar proteins to be preferentially carbonylated or degraded in states of enhanced ROS generation
    • M Fedorova N Kuleva R Hoffmann 2010 Identification, quantification, and functional aspects of skeletal muscle protein-carbonylation in vivo during acute oxidative stress J Proteome Res 9 5 2516 2526 1:CAS:528:DC%2BC3cXkvFaqt7Y%3D 10.1021/pr901182r 20377239 A series of recent papers from this group used an x-ray irradiation model of acute ROS production to study the dynamics and functional consequences of oxidative damage to sarcomeric proteins. Importantly, they found myofibrillar proteins to be preferentially carbonylated or degraded in states of enhanced ROS generation
    • (2010) J Proteome Res , vol.9 , Issue.5 , pp. 2516-2526
    • Fedorova, M.1    Kuleva, N.2    Hoffmann, R.3
  • 37
    • 36248973660 scopus 로고    scopus 로고
    • Peroxynitrite inhibits myofibrillar protein function in an in vitro assay of motility
    • DOI 10.1016/j.freeradbiomed.2007.09.004, PII S0891584907005953
    • JH Snook J Li BP Helmke WH Guilford 2008 Peroxynitrite inhibits myofibrillar protein function in an in vitro assay of motility Free Radic Biol Med 44 1 14 23 1:CAS:528:DC%2BD2sXhtlyrurnI 10.1016/j.freeradbiomed.2007.09.004 18045543 (Pubitemid 350138626)
    • (2008) Free Radical Biology and Medicine , vol.44 , Issue.1 , pp. 14-23
    • Snook, J.H.1    Li, J.2    Helmke, B.P.3    Guilford, W.H.4
  • 38
    • 67349256143 scopus 로고    scopus 로고
    • Adrenaline and reactive oxygen species elicit proteome and energetic metabolism modifications in freshly isolated rat cardiomyocytes
    • 1:CAS:528:DC%2BD1MXmtlOhsro%3D 10.1016/j.tox.2009.03.012 19464573
    • VM Costa R Silva LC Tavares, et al. 2009 Adrenaline and reactive oxygen species elicit proteome and energetic metabolism modifications in freshly isolated rat cardiomyocytes Toxicology 260 1-3 84 96 1:CAS:528: DC%2BD1MXmtlOhsro%3D 10.1016/j.tox.2009.03.012 19464573
    • (2009) Toxicology , vol.260 , Issue.13 , pp. 84-96
    • Costa, V.M.1    Silva, R.2    Tavares, L.C.3
  • 39
    • 34247880194 scopus 로고    scopus 로고
    • Myofibrillar protein oxidation and contractile dysfunction in hyperthyroid rat diaphragm
    • DOI 10.1152/japplphysiol.01177.2006
    • T Yamada T Mishima M Sakamoto, et al. 2007 Myofibrillar protein oxidation and contractile dysfunction in hyperthyroid rat diaphragm J Appl Physiol 102 5 1850 1855 1:CAS:528:DC%2BD2sXmt1aqsL4%3D 10.1152/japplphysiol.01177.2006 17303704 (Pubitemid 46701954)
    • (2007) Journal of Applied Physiology , vol.102 , Issue.5 , pp. 1850-1855
    • Yamada, T.1    Mishima, T.2    Sakamoto, M.3    Sugiyama, M.4    Matsunaga, S.5    Wada, M.6
  • 40
    • 1342304174 scopus 로고    scopus 로고
    • Evidence of myofibrillar protein oxidation induced by postischemic reperfusion in isolated rat hearts
    • 1:CAS:528:DC%2BD2cXitlShsrY%3D 10.1152/ajpheart.00714.2003 14766672
    • M Canton I Neverova R Menabo, et al. 2004 Evidence of myofibrillar protein oxidation induced by postischemic reperfusion in isolated rat hearts Am J Physiol Heart Circ Physiol 286 3 H870 H877 1:CAS:528:DC%2BD2cXitlShsrY%3D 10.1152/ajpheart.00714.2003 14766672
    • (2004) Am J Physiol Heart Circ Physiol , vol.286 , Issue.3
    • Canton, M.1    Neverova, I.2    Menabo, R.3
  • 42
    • 71849118358 scopus 로고    scopus 로고
    • Reversible and irreversible modifications of skeletal muscle proteins in a rat model of acute oxidative stress
    • 1:CAS:528:DC%2BD1MXhsVKntrnF 19786098
    • M Fedorova N Kuleva R Hoffmann 2009 Reversible and irreversible modifications of skeletal muscle proteins in a rat model of acute oxidative stress Biochim Biophys Acta 1792 12 1185 1193 1:CAS:528:DC%2BD1MXhsVKntrnF 19786098
    • (2009) Biochim Biophys Acta , vol.1792 , Issue.12 , pp. 1185-1193
    • Fedorova, M.1    Kuleva, N.2    Hoffmann, R.3
  • 44
    • 55849141926 scopus 로고    scopus 로고
    • Changes in actin structural transitions associated with oxidative inhibition of muscle contraction
    • 1:CAS:528:DC%2BD1cXht1Clur7N 10.1021/bi801080x 18855423
    • E Prochniewicz D Spakowicz DD Thomas 2008 Changes in actin structural transitions associated with oxidative inhibition of muscle contraction Biochemistry 47 45 11811 11817 1:CAS:528:DC%2BD1cXht1Clur7N 10.1021/bi801080x 18855423
    • (2008) Biochemistry , vol.47 , Issue.45 , pp. 11811-11817
    • Prochniewicz, E.1    Spakowicz, D.2    Thomas, D.D.3
  • 45
    • 77949837372 scopus 로고    scopus 로고
    • Identification of cysteine, methionine and tryptophan residues of actin oxidized in vivo during oxidative stress
    • 1:CAS:528:DC%2BC3cXhtFKqurw%3D 10.1021/pr901099e 20063901
    • M Fedorova N Kuleva R Hoffmann 2010 Identification of cysteine, methionine and tryptophan residues of actin oxidized in vivo during oxidative stress J Proteome Res 9 3 1598 1609 1:CAS:528:DC%2BC3cXhtFKqurw%3D 10.1021/pr901099e 20063901
    • (2010) J Proteome Res , vol.9 , Issue.3 , pp. 1598-1609
    • Fedorova, M.1    Kuleva, N.2    Hoffmann, R.3
  • 48
    • 33645023189 scopus 로고    scopus 로고
    • Oxidative modification of tropomyosin and myocardial dysfunction following coronary microembolization
    • 1:CAS:528:DC%2BD28XjvFOntb4%3D 10.1093/eurheartj/ehi751 16434410
    • M Canton A Skyschally R Menabo, et al. 2006 Oxidative modification of tropomyosin and myocardial dysfunction following coronary microembolization Eur Heart J 27 7 875 881 1:CAS:528:DC%2BD28XjvFOntb4%3D 10.1093/eurheartj/ehi751 16434410
    • (2006) Eur Heart J , vol.27 , Issue.7 , pp. 875-881
    • Canton, M.1    Skyschally, A.2    Menabo, R.3
  • 49
    • 33750822268 scopus 로고    scopus 로고
    • Right ventricular contractile protein function in rats with left ventricular myocardial infarction
    • 8760160
    • PP De Tombe T Wannenburg D Fan WC Little 1996 Right ventricular contractile protein function in rats with left ventricular myocardial infarction Am J Physiol 271 1 Pt 2 H73 H79 8760160
    • (1996) Am J Physiol , vol.271 , Issue.1 PART 2
    • De Tombe, P.P.1    Wannenburg, T.2    Fan, D.3    Little, W.C.4
  • 50
    • 0036776128 scopus 로고    scopus 로고
    • Hypothesis: Troponin degradation is one of the factors responsible for deterioration of left ventricular function in heart failure
    • DOI 10.1016/S0008-6363(02)00534-5, PII S0008636302005345
    • A van der Laarse 2002 Hypothesis: troponin degradation is one of the factors responsible for deterioration of left ventricular function in heart failure Cardiovasc Res 56 1 8 14 10.1016/S0008-6363(02)00534-5 12237161 (Pubitemid 35247797)
    • (2002) Cardiovascular Research , vol.56 , Issue.1 , pp. 8-14
    • Van Der Laarse, A.1
  • 52
    • 0037030584 scopus 로고    scopus 로고
    • Induction of protein catabolism and the ubiquitin-proteasome pathway by mild oxidative stress
    • DOI 10.1016/S0304-3835(02)00006-X, PII S030438350200006X
    • MC Gomes-Marcondes MJ Tisdale 2002 Induction of protein catabolism and the ubiquitin-proteasome pathway by mild oxidative stress Cancer Lett 180 69 74 1:CAS:528:DC%2BD38XitFWmsro%3D 10.1016/S0304-3835(02)00006-X 11911972 (Pubitemid 34242966)
    • (2002) Cancer Letters , vol.180 , Issue.1 , pp. 69-74
    • Gomes-Marcondes, M.C.C.1    Tisdale, M.J.2
  • 53
    • 77649254844 scopus 로고    scopus 로고
    • Ubiquitin proteasome dysfunction in human hypertrophic and dilated cardiomyopathies
    • 1:CAS:528:DC%2BC3cXisFOlsLk%3D 10.1161/CIRCULATIONAHA.109.904557 20159828
    • JM Predmore P Wang F Davis, et al. 2010 Ubiquitin proteasome dysfunction in human hypertrophic and dilated cardiomyopathies Circulation 121 997 1004 1:CAS:528:DC%2BC3cXisFOlsLk%3D 10.1161/CIRCULATIONAHA.109.904557 20159828
    • (2010) Circulation , vol.121 , pp. 997-1004
    • Predmore, J.M.1    Wang, P.2    Davis, F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.