Involvement of the nitric oxide pathway in the anticonvulsant effect of tramadol on pentylenetetrazole-induced seizures in mice

Epilepsy and Behavior

Volumn 19, Issue 3, 2010, Pages 290-295

  Lesani, Ali ^a,b   Javadi Paydar, Mehrak ^a,c   Khodadad, Tina Kabiri ^d   Asghari Roodsari, Alaleh ^a,b   Shirkhodaei, Mahyar ^a   Norouzi, Abbas ^c   Dehpour, Ahmad Reza ^a  

^a TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^d ISLAMIC AZAD UNIVERSITY   (Iran)

Author keywords

Mice; Nitric oxide; Nitric oxide synthase inhibitors; Pentylenetetrazole; Seizure threshold; Tramadol

Indexed keywords

ARGININE; N(G) NITROARGININE METHYL ESTER; NALOXONE; NITRIC OXIDE; OPIATE RECEPTOR; PENTETRAZOLE; TRAMADOL;

ACUTE DRUG ADMINISTRATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTICONVULSANT ACTIVITY; ARTICLE; CLONIC SEIZURE; DOSE TIME EFFECT RELATION; DRUG EFFICACY; DRUG INHIBITION; DRUG MEGADOSE; DRUG POTENTIATION; MALE; MOUSE; NONHUMAN; SEIZURE THRESHOLD;

ANALYSIS OF VARIANCE; ANIMALS; ANTICONVULSANTS; ARGININE; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; ENZYME INHIBITORS; MALE; MICE; MICE, INBRED STRAINS; NALOXONE; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE; PENTYLENETETRAZOLE; SEIZURES; SIGNAL TRANSDUCTION; TIME FACTORS; TRAMADOL;

EID: 78649907121     PISSN: 15255050     EISSN: 15255069     Source Type: Journal    
DOI: 10.1016/j.yebeh.2010.08.006     Document Type: Article

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