A microscopic study of granulation mechanisms and their effect on granule properties

Powder Technology

Volumn 206, Issue 1-2, 2011, Pages 18-24

  Le, Phung K ^a,c   Avontuur, Paul ^b   Hounslow, Michael J ^a   Salman, Agba D ^a  

^a UNIVERSITY OF SHEFFIELD   (United Kingdom)

^b GLAXOSMITHKLINE   (United Kingdom)

^c Vietnam National University Ho Chi Minh   (Namibia)

Author keywords

Binder distribution; Coalescence; Consolidation; High shear granulation; Nucleation

Indexed keywords

BINDER CONTENT; BINDER DISTRIBUTION; COMPETING MECHANISMS; DISSOLUTION RATES; GRANULATION MECHANISM; GRANULE FORMATIONS; GRANULE PROPERTIES; GRANULE STRUCTURE; HIGH-SHEAR GRANULATION; INDUSTRIAL PRACTICES; INHOMOGENEITIES; MICROSCOPIC STUDY; PROCESS DEVELOPMENT; SAMPLING TIME; SINGLE GRANULE;

BINDERS; COALESCENCE; DISSOLUTION; NUCLEATION;

GRANULATION;

ARTICLE; CHEMICAL BINDING; CHEMICAL COMPOSITION; CHEMICAL REACTION; CHEMICAL STRUCTURE; DISSOLUTION; GRANULATION; IMAGE ANALYSIS; MICROSCOPY; MOLECULAR IMAGING; PARTICLE SIZE; POROSITY; PROCESS DESIGN; PROCESS TECHNOLOGY; SHEAR STRENGTH;

EID: 78649906562     PISSN: 00325910     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.powtec.2010.06.014     Document Type: Article

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