The value of p16ink4a expression by fluorescence in situ hybridization in triage for high risk HPV positive in cervical cancer screening

Gynecologic Oncology

Volumn 120, Issue 1, 2011, Pages 84-88

  Zeng, Wen Jie ^a   Li, Ying ^a   Fei, Hua Li ^a   Cheng, Xiao Dong ^b   Ye, Feng ^a,b   Lü, Wei Guo ^b   Xie, Xing ^b  

^a Women's Reproductive Health Laboratory of Zhejiang Province   (China)

^b ZHEJIANG UNIVERSITY   (China)

Author keywords

Cervical cancer; FISH; HPV; P16ink4a; Screening method

Indexed keywords

BIOLOGICAL MARKER; CYCLIN DEPENDENT KINASE INHIBITOR 2A; VIRUS DNA;

ARTICLE; CANCER GRADING; CANCER SCREENING; COLPOSCOPY; CONTROLLED STUDY; COPY NUMBER VARIATION; DIAGNOSTIC ACCURACY; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; GENE EXPRESSION; HIGH RISK PATIENT; HUMAN; HUMAN CELL; HUMAN TISSUE; MAJOR CLINICAL STUDY; NONHUMAN; PAPILLOMAVIRUS INFECTION; PREDICTION; PRIORITY JOURNAL; SENSITIVITY AND SPECIFICITY; UTERINE CERVIX BIOPSY; UTERINE CERVIX CARCINOMA; UTERINE CERVIX CARCINOMA IN SITU; UTERINE CERVIX CYTOLOGY; VIRUS LOAD;

ADULT; CERVICAL INTRAEPITHELIAL NEOPLASIA; CYCLIN-DEPENDENT KINASE INHIBITOR P16; DNA, VIRAL; EARLY DETECTION OF CANCER; FEMALE; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; MIDDLE AGED; PAPILLOMAVIRIDAE; PAPILLOMAVIRUS INFECTIONS; RISK FACTORS; UTERINE CERVICAL NEOPLASMS; YOUNG ADULT;

EID: 78649904253     PISSN: 00908258     EISSN: 10956859     Source Type: Journal    
DOI: 10.1016/j.ygyno.2010.09.008     Document Type: Article

References (26)

1. A. Meisels, and R. Fortein Condylomatous lesions of the cervix and vagina.I. Cytologic patterns Acta Cytol 20 1976 505 509
2. J.M. Walboomers, M.V. Jacobs, M.M. Manos, F.X. Bosch, J.A. Kummer, and K.V. Shah Human papillomavirus is a necessary cause of invasive cervical cancer worldwide J Pathol 189 1999 1 3
3. J. Cuzick Role of HPV testing in clinical practice Virus Res 89 2 2002 Nov 263 269
4. J. Cuzick, C. Clavel, K.U. Petry, C.J. Meijer, H. Hoyer, and S. Ratnam Overview of the European and North American studies on HPV testing in primary cervical cancer screening Int J Cancer 119 5 2006 Sep 1 1095 1101
5. Lörincz AT, and R.M. Richart Human papillomavirus DNA testing as an adjunct to cytology in cervical screening programs Arch Pathol Lab Med 127 2003 959 968
6. C.V. Biscotti, A.E. Dawson, B. Dziura, L. Galup, T. Darragh, and A. Rahemtulla Assisted primary screening using the automated ThinPrep Imaging System Am J Clin Pathol 123 2005 281 287
7. B. Dziura, S. Quinn, and K. Richard Performance of an imaging system vs. manual screening in the detection of squamous intraepithelial lesions of the uterine cervix Acta Cytol 50 2006 309 311
8. A. Grace, P. McBrearty, S. Troost, M. Thonhill, E. Kay, and M. Leader Comparative study: conventional cervical and ThinPrep Pap tests in a routine clinical setting Cytopathol 13 2002 200 205
9. S.J. Bernstein, L. Sanchez-Ramos, and B. Ndubisi Liquid-based cervical cytologic smear study and conventional Papanicolaou smears: a metaanalysis of prospective studies comparing cytologic diagnosis and sample adequacy Am J Obstet Gynecol 185 2001 308 317
10. Y. Li, F. Ye, W.G. Lu, W.J. Zeng, L.H. Wei, and X. Xie Detection of hTERC in cervical cancer and precancerous lesions, comparison with cytologic and HPV DNA test Int J Gynecol Cancer 20 May 2010 631 637
11. D. Dehn, K.C. Torkko, and K.R. Shroyer Human papillomavirus testing and molecular markers of cervical dysplasia and carcinoma Cancer 111 1 2007 Feb 25 1 14
12. L.C. Horn, A. Reichert, A. Oster, S.F. Arndal, M.J. Trunk, and R. Ridder Immunostaining for p16INK4a used as a conjunctive tool improves interobserver agreement of the histologic diagnosis of cervical intraepithelial neoplasia Am J Surg Pathol 32 2008 502 512
13. F. Carozzi, M. Confortini, P. Dalla Palma, A. Del Mistro, A. Gillio-Tos, and L. De Marco Use of p16-INK4A overexpression to increase the specificity of human papillomavirus testing: a nested substudy of the NTCC randomised controlled trial Lancet Oncol 9 2008 937 945
14. J.T. Cox History of the use of HPV testing in cervical screening and in the management of abnormal cervical screening results J Clin Virol 45 Suppl 1 2009 Jul S3 S12
15. D. Solomon, D. Davey, R. Kurman, A. Moriarty, D. O'Connor, and M. Prey The 2001 Bethesda system: terminology for reporting results of cervical cytology JAMA 287 2002 2114 2119
16. P. Sasieni, and J. Cuzick Can HPV testing become the sole primary cervical screening test? J Med Screen 9 2002 49 51
17. I. Kotaniemi-Talonen, P. Nieminen, A. Anttila, and M. Hakama Routine cervical with primary HPV testing and cytology triage protocol in a randomised setting Brit J Cancer 93 2005 862 867
18. A.B. Moscicki, S. Shiboski, N.K. Hills, K.J. Powell, N. Jay, and E.N. Hanson Regression of low-grade squamous intra-epithelial lesions in young women Lancet 364 9446 2004 Nov 6-12 1678 1683
19. P.D. Sasieni, J. Cuzick, and E. Lynch-Farmery Estimating the efficacy of screening by auditing smear histories of women with and without cervical cancer Br J Cancer 73 1996 1001 1005
20. P.S. Bernard, and C.T. Wittwer Real-time PCR technology for cancer diagnostics Clin Chem 48 8 2002 Aug 1178 1185
21. I. Tsoumpou, M. Arbyn, M. Kyrgiou, N. Wentzensen, G. Koliopoulos, and P. Martin-Hirsch p16(INK4a) immunostaining in cytological and histological specimens from the uterine cervix: a systematic review and meta-analysis Cancer Treat Rev 35 3 2009 May 210 220
22. A. Maitra, D. Wanzer, A.G. Weinberg, and R. Ashfaq Amplification of the HER-2/neu oncogene is uncommon in pediatric osteosarcomas Cancer 92 3 2001 Aug 1 677 683
23. G. Volgareva, L. Zavalishina, Y. Andreeva, G. Frank, E. Krutikova, and D. Golovina Protein p16 as a marker of dysplastic and neoplastic alterations in cervical epithelial cells BMC Cancer 4 2004 58
24. A.A. Bahnassy, A.R. Zekri, M. Saleh, M. Lotayef, M. Moneir, and O. Shawki The possible role of cell cycle regulators in multistep process of HPV-associated cervical carcinoma BMC Clin Pathol 7 2007 4
25. W. Yi, J.L. Wang, X.H. Li, and L.H. Wei Correlations of high-risk human papillomaviral load to cervical intraepithelial neoplasia grades, expression of Ki-67 and P6ink4a and follow-up Ai Zheng 27 5 2008 May 520 524
26. P.C. Giraldo, D.I. Cavalcante, A.K. Gonçalves, A.K. Gonçalves, and R.M. Eleutério Association between high risk HPV viral load, p16ink4a expression and intra-epithelial cervical lesions Rev Assoc Méd Bras 53 6 2007 Nov-Dec 530 534