Immunogenicity and impact on nasopharyngeal carriage of a nonavalent pneumococcal conjugate vaccine

Journal of Infectious Diseases

Volumn 180, Issue 4, 1999, Pages 1171-1176

  Mbelle, Nontombi ^a   Huebner, Robin E ^a   Wasas, Avril D ^a   Kimura, Alan ^b   Chang, Ih ^b   Klugman, Keith P ^a,c  

^a SOUTH AFRICAN MEDICAL RESEARCH COUNCIL   (South Africa)

^b PFIZER INC   (United States)

^c NATIONAL HEALTH LABORATORY SERVICE   (South Africa)

Author keywords

[No Author keywords available]

Indexed keywords

DIPHTHERIA ANTIBODY; PNEUMOCOCCUS VACCINE;

ANTIBODY RESPONSE; ANTIBODY TITER; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIPHTHERIA; DOUBLE BLIND PROCEDURE; HAEMOPHILUS INFLUENZAE TYPE B; HUMAN; IMMUNOGENICITY; INFANT; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RHINOPHARYNGITIS; STREPTOCOCCUS PNEUMONIAE; VACCINATION;

CARRIER STATE; DIPHTHERIA-TETANUS-PERTUSSIS VACCINE; DOUBLE-BLIND METHOD; HAEMOPHILUS INFLUENZAE; HAEMOPHILUS VACCINES; HUMANS; IMMUNIZATION SCHEDULE; INFANT; NASOPHARYNX; PENICILLIN RESISTANCE; SEROTYPING; SOUTH AFRICA; STREPTOCOCCUS PNEUMONIAE; TRIMETHOPRIM RESISTANCE; TRIMETHOPRIM-SULFAMETHOXAZOLE COMBINATION; VACCINES, CONJUGATE;

EID: 0033394801     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1086/315009     Document Type: Article

References (32)

1. Garenne M, Ronsmans C, Campbell H. The magnitude of mortality from acute respiratory infections in children under 5 years in developing countries. World Health Statist Quart 1992;45:180-91.
2. Adegbola RA, Falade AG, Sam BE, et al. The actiology of pneumoniae in malnourished and well nourished Gambian children. Pediatr Infect Dis J 1994;13:975-82.
3. Ikeogu MO. Acute pneumonia in Zimbabwe: bacterial isolates by lung aspirates. Arch Dis Child 1998;25:1266-7.
4. Crewe-Brown HH, Karstaedt AS, Saunders GL, et al. S. pneumoniae bacteremia and HIV infection: alteration in penicillin susceptibility and serogroups/types. Clin Infect Dis 1997;25:1165-72.
5. Centers for Disease Control and Prevention. Progress towards climination of Haemophilus influenzae disease among infants and children-United States 19934. MMWR Morb Mortal Wkly Rep 1995;44:545-50.
6. Peltola H, Kilpi T, Anttila M. Rapid disappearance of H. influenzae type b meningitis after routine childhood immunisation with conjugate vaccines. Lancet 1992;340:592-4.
7. 195 vaccines. Effect of saccharide size on immunogenicity and interactions with simultaneously administered vaccines. J Infect Dis 1997;176:445-55.
8. Siber, GR, Pneumococcal disease: prospects of a new generation of vaccines. Science 1994;265:1385-7.
9. 197 in United States infants. Pediatrics 1998;101:604-11.
10. Sniadeck DH, Schwartz B, Lipman H, et al. Potential interventions for the prevention of childhood pneumonia: geographic and temporal differences in serotype and serogroup distribution of sterile site pneumococcal isolates from children - Implications for vaccine strategies. Pediatr Infect Dis J 1995;14:503-516.
11. Wasas A, Huebner R, Klugman KP. Trends in serotypes/groups of pneumococci and pneumococcal diseases in South Africa. In: Proceedings of the 1st International Symposium on Pneumococci and Pneumococcal Diseases. Copenhagen: Statens Serum Institute, 1998:22.
12. Klugman KP, Friedland IR. Antibiotic-resistant pneumococci in paediatric diseases. Microb Drug Resist 1995;1:5-8.
13. Capeding M, Nohynek H, Sombrero L, et al. Evaluation of sampling sites for detection of upper respiratory tract carriage of S. pneumoniae and H. influenzae type b among healthy Filipino infants. J Clin Microbiol 1995;33:3077-9.
14. National Committee for Clinical Laboratory Standards. Performance standards for antimicrobial susceptibility testing: 8th informational supplement. Wayne, PA: NCCLS, 1998;M100 S8.
15. Quataert SA, Kirch C, Wield L, et al. Assignment of weight based antibody units to human pneumococcal standard reference serum. Clin Diagn Lab Immunol 1995;2:590-7.
16. Phipps DC, West J, Eby R, Koster M, Madore DV, Quataert SA. An ELISA employing a Haemophilus influenzae type b oligosaccharide-human serum albumin conjugate correlates with the radioantigen binding assay. J Immunol Methods 1990;135:121-8.
17. Paradiso PR, Hogerman DA, Madore DV, et al. Safety and immunogenicity of a combined diphtheria, tetanus, pertussis, and Haemophilus influenzae type b vaccine in young infants. Pediatrics 1993;92:827-32.
18. Ward J, Brenneman G, Letson GN, Heyward W, and the Alaska H. influenzae Vaccine Study Group. Limited efficacy of a H. influenzae type b conjugate vaccine in Alaska Native infants. New Engl J Med 1990;323:1393-401.
19. Ahman H, Kayhty H, Eskola J. Immunogenicity of heptavalent pneumococcal conjugate vaccine in infants [abstract 58]. In: Proceedings of the European Society for Paediatric Infectious Diseases. Paris: ESPID, 1997:29.
20. Stack AM, Malley R, Thompson CM, Kobzik L, Siber GR, Saladino RA. Minimum protective serum concentrations of pneumococcal anti-capsular antibodies in infant rats. J Infect Dis 1998;177:986-90.
21. Anderson EL, Kennedy DJ, Geldmacher KM, Donnelly J, Mendelman P. Immunogenicity of heptavalent pneumococcal conjugate vaccine in infants. J Pediatr 1996;128:649-53.
22. Leach AJ, Boswell JB, Asche V, Nienhuys TG. Bacterial colonization of the nasopharynx predicts very early onset and persistence of otitis media in Australian aboriginal infants. Pediatr Infect Dis J 1994;13:983-9.
23. Koornhof HJ, Wasas A, Klugman K. Antimicrobial resistance in Streptococcus pneumoniae: a South African perspective. Clin Infect Dis 1992;15:84-94.
24. Mastro T, Ghafoor A, Nomani N, Ishsq Z, Anwar F, Granoff D, Use of nasopharyngeal isolates of Streptococcus pneumoniae and Haemophilus influenzae from children in Pakistan for surveillance of antimicrobial resistance. Pediatr Infect Dis J 1993;12:824-30.
25. Yagupsky P, Peled N, Dagan R. Pneumococcal isolates from the nasopharynx of healthy children reflect serogroup distribution and antimicrobial resistance patterns of clinically significant pneumococci in young children [abstract C48]. In: Program and abstracts of the 36th Interscience Conference on Antimicrobial Agents and Chemotherapeutics. New Orleans: ASM, 1996:43.
26. Kellner JD, McGeer A, Wenger J, et al. What is the correlation between population-based collections of invasive and nasopharyngeal isolates of Streptococcus pneumoniae? [abstract C49] In: Program and abstracts of the 36th Interscience Conference on Antimicrobial Agents and Chemotherapeutics. New Orleans: ASM, 1996:43.
27. Obaro SK, Adegbola RA, Banya W, Greenwood B. Carriage of pneumococci after pneumococcal vaccination. Lancet 1996;348:271-2.
28. Dagan R, Melamed R, Muallem M, et al. Reduction of nasopharyngeal carriage of pneumococci during the second year of life by a heptavalent pneumococcal conjugate vaccine. J Infect Dis 1996;174:1271-831.
29. Van Dam JEG, Fleer A, Snippe H. Immunogenicity and immunochemistry of Streptococcus pneumoniae capsular polysaccharide. Antonic van Leeuwenhock 1990;58:1-47.
30. Nahm MH, Olander JV, Magyarlaki M. Identification of cross-reactive antibodies with low opsonophagocytic activity for Streptococcus pneumoniae. J Infect Dis 1997;176:698-703.
31. Coffey TJ, Dowson CG, Daniels M, et al. Horizontal transfer of multiple penicillin-binding protein genes and capsular biosynthetic genes in natural populations of Streplococcus pneumoniae. Mol Biol 1991;5:2255-60.
32. Austrian R. Some aspects of the pneumococcal carrier state. J Antimicrob Chemother 1986;(suppl A):35-45.