Étude de l'expression des kinases Aurora dans le carcinome à cellules rénales;Study of the expression of Aurora kinases in renal cell carcinoma

Progres en Urologie

Volumn 20, Issue 13, 2010, Pages 1200-1205

  Mathieu, R ^a   Patard, J J ^a,b   Stock, N ^b   Rioux Leclercq, N ^b   Guille F ^a   Fergelot, P ^b   Bensalah, K ^a,b  

^a PONTCHAILLOU UNIVERSITY HOSPITAL   (France)

^b UNIVERSITÉ DE RENNES 1   (France)

Author keywords

Aurora kinases; Lymph node invasion; Renal cell carcinoma; Targeted therapy

Indexed keywords

AURORA KINASE; PROTEIN SERINE THREONINE KINASE;

ADULT; AGED; ARTICLE; BIOSYNTHESIS; HUMAN; KIDNEY CARCINOMA; KIDNEY TUMOR; METABOLISM; MIDDLE AGED; RETROSPECTIVE STUDY;

ADULT; AGED; AGED, 80 AND OVER; CARCINOMA, RENAL CELL; HUMANS; KIDNEY NEOPLASMS; MIDDLE AGED; PROTEIN-SERINE-THREONINE KINASES; RETROSPECTIVE STUDIES;

EID: 78649888458     PISSN: 11667087     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.purol.2010.05.005     Document Type: Article

References (21)

1. Pantuck A.J., Zisman A., Belldegrun A.S. The changing natural history of renal cell carcinoma. J Urol 2001, 166:1611-1623.
2. Motzer R.J., Mazumdar M., Bacik J., Berg W., Amsterdam A., Ferrara J. Survival and prognostic stratification of 670 patients with advanced renal cell carcinoma. J Clin Oncol 1999, 17:2530-2540.
3. Clark J.I., Atkins M.B., Urba W.J., Creech S., Figlin R.A., Dutcher J.P., et al. Adjuvant high-dose bolus interleukin-2 for patients with high-risk renal cell carcinoma: a cytokine working group randomized trial. J Clin Oncol 2003, 21:3133-3140.
4. Motzer R.J., Hutson T.E., Tomczak P., Michaelson M.D., Bukowski R.M., Oudard S., et al. Overall survival and updated results for sunitinib compared with interferon alfa in patients with metastatic renal cell carcinoma. J Clin Oncol 2009, 27(22):3584-3590.
5. Bolanos-Garcia V.M. Aurora kinases. Int J Biochem Cell Biol 2005, 37:1572-1577.
6. Jeng Y.M., Peng S.Y., Lin C.Y., Hsu H.C. Overexpression and amplification of Aurora-A in hepatocellular carcinoma. Clin Cancer Res 2004, 10:2065-2071.
7. Bischoff J.R., Anderson L., Zhu Y., Mossie K., Ng L., Souza B., et al. A homologue of Drosophila aurora kinase is oncogenic and amplified in human colorectal cancers. EMBO J 1998, 17:3052-3065.
8. Hoque A., Carter J., Xia W., Hung M.C., Sahin A.A., Sen S., et al. Loss of aurora A/STK15/BTAK overexpression correlates with transition of in situ to invasive ductal carcinoma of the breast. Cancer Epidemiol Biomarkers Prev 2003, 12:1518-1522.
9. Matthews N., Visintin C., Hartzoulakis B., Jarvis A., Selwood D.L. Aurora A and B kinases as targets for cancer: will they be selective for tumors?. Expert Rev Anticancer Ther 2006, 6:109-120.
10. Adams R.R., Eckley D.M., Vagnarelli P., Wheatley S.P., Gerloff D.L., Mackay A.M., et al. Human INCENP colocalizes with the Aurora-B/AIRK2 kinase on chromosomes and is overexpressed in tumour cells. Chromosoma 2001, 110:65-74.
11. Carpinelli P., Moll J. Is there a future for Aurora kinase inhibitors for anticancer therapy?. Curr Opin Drug Discov Devel 2009, 12(4):533-542.
12. Bassil B., Dosoretz D.E., Prout G.R. Validation of the tumor, nodes and metastasis classification of renal cell carcinoma. J Urol 1985, 134:450-454.
13. Giet R., Petretti C., Prigent C. Aurora kinases, aneuploidy and cancer, a coincidence or a real link?. Trends Cell Biol 2005, 15:241-250.
14. Rojanala S., Han H., Munoz R.M., Browne W., Nagle R., Von Hoff D.D., et al. The mitotic serine threonine kinase Aurora-2, is a potential target for drug development in human pancreatic cancer. Mol Cancer Ther 2004, 3:451-457.
15. Gritsko T.M., Coppola D., Paciga J.E., Yang L., Sun M., Shelley S.A., et al. Activation and overexpression of centrosome kinase BTAK/Aurora-A in human ovarian cancer. Clin Cancer Res 2003, 9:1420-1426.
16. Chieffi P., Cozzolino L., Kisslinger A., Libertini S., Staibano S., Mansueto G., et al. Aurora B expression directly correlates with prostate cancer malignancy and influence prostate cell proliferation. Prostate 2006, 66:326-333.
17. Sen S., Zhou H., Zhang R.D., Yoon D.S., Vakar-Lopez F., Ito S., et al. Amplification/overexpression of a mitotic kinase gene in human bladder cancer. J Natl Cancer Inst 2002, 94:1320-1329.
18. Cha T.L., Chuang M.J., Wu S.T., Sun G.H., Chang S.Y., Yu D.S., et al. Dual degradation of aurora A and B kinases by the histone deacetylase inhibitor LBH589 induces G2-M arrest and apoptosis of renal cancer cells. Clin Cancer Res 2009, 15(3):840-850.
19. Cheville J.C., Lohse C.M., Zincke H., et al. Comparisons of outcome and prognostic features among histologic subtypes of renal cell carcinoma. Am J Surg Pathol 2003, 27:612-624.
20. Patard J.J., Leray E., Rioux-Leclercq N., Cindolo L., Ficarra V., Zisman A., et al. Prognostic value of histologic subtypes in renal cell carcinoma: a multicenter experience. J Clin Oncol 2005, 23:2763-2771.
21. Kurahashi T., Miyake H., Hara I., Fujisawa M. Significance of Aurora-A expression in renal cell carcinoma. Urol Oncol 2007, 25:128-133.