IL-32 is increased along with tryptase in lesional psoriatic skin and is up-regulated by substance P in human mast cells

European Journal of Dermatology

Volumn 20, Issue 6, 2010, Pages 865-867

  Kempuraj, Duraisamy ^a   Conti, Pio ^b   Vasiadi, Magdalini ^a   Alysandratos, Konstantinos Dionysios ^a   Tagen, Michael ^a   Kalogeromitros, Dimitrios ^c   Kourelis, Taxiarchis ^a   Gregoriou, Stamatios ^c   Makris, Michael ^c   Stavrianeas, Nikolaos G ^c   Theoharides, Theoharis C ^a  

^a TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CHIETI   (Italy)

^c UNIVERSITY OF ATHENS MEDICAL SCHOOL   (Greece)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 32; SUBSTANCE P; TRYPTASE; TUMOR NECROSIS FACTOR;

ADULT; CLINICAL ARTICLE; FEMALE; GENE EXPRESSION; HUMAN; HUMAN CELL; KERATINOCYTE; LETTER; MALE; MAST CELL; PSORIASIS; SKIN BIOPSY; UPREGULATION;

BIOPSY; FEMALE; GENE EXPRESSION; HUMANS; IMMUNOHISTOCHEMISTRY; INTERLEUKINS; MALE; MAST CELLS; MIDDLE AGED; POLYMERASE CHAIN REACTION; PSORIASIS; SEVERITY OF ILLNESS INDEX; SUBSTANCE P; TRYPTASES; UP-REGULATION;

EID: 78649866448     PISSN: 11671122     EISSN: 19524013     Source Type: Journal    
DOI: 10.1684/ejd.2010.1110     Document Type: Letter

References (6)

1. Nestle FO, Kaplan DH, Barker J. Psoriasis. N Engl J Med 2009; 361: 496-509
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3. Remröd C, Lonne-Rahm S, Nordliond K. Study of substance P and its receptor neurokinin-1 in psoriasis and their relation to chronic stress and pruritus. Arch Dermatol Res 2007; 299: 85-91.
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6. Meyer N, Zimmermann M, Burgler S, et al. IL-32 is expressed by human primary keratinocytes and modulates keratinocyte apoptosis in atopic dermatitis. J Allergy Clin Immunol 2010; 125: 858-65.