Editorial: Ancestry, ancestry-informative markers, asthma, and the quest for personalized medicine

Journal of Allergy and Clinical Immunology

Volumn 126, Issue 6, 2010, Pages 1139-1140

  Barnes, Kathleen C ^a  

^a JOHNS HOPKINS ASTHMA AND ALLERGY CENTER   (United States)

Author keywords

Admixture mapping; ancestry informative markers (AIMs); ethnicity

Indexed keywords

ANTIINFLAMMATORY AGENT; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; CORTICOSTEROID; SALMETEROL; BIOLOGICAL MARKER;

ASTHMA; BODY MASS; EDITORIAL; ETHNICITY; GENETIC ASSOCIATION; GENETIC VARIABILITY; HUMAN; MEDICINE; PERSONALIZED MEDICINE; PRIORITY JOURNAL; SELF REPORT; SINGLE NUCLEOTIDE POLYMORPHISM; TREATMENT RESPONSE; CLINICAL TRIAL (TOPIC); GENETIC POLYMORPHISM; IMMUNOLOGY; METABOLISM; METHODOLOGY; NOTE; PHARMACOGENETICS; PROGNOSIS; RACE; UNITED STATES;

ASTHMA; BIOLOGICAL MARKERS; CLINICAL TRIALS AS TOPIC; CONTINENTAL POPULATION GROUPS; HUMANS; INDIVIDUALIZED MEDICINE; PHARMACOGENETICS; POLYMORPHISM, GENETIC; PROGNOSIS; UNITED STATES;

EID: 78649859185     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jaci.2010.10.032     Document Type: Editorial

References (15)

1. M.A. Hamburg, and F.S. Collins The path to personalized medicine N Engl J Med 363 2010 301 304
2. D.A. Meyers Genetics of asthma and allergy: what have we learned? J Allergy Clin Immunol 126 2010 439 448
3. J.E. Moorman, R.A. Rudd, C.A. Johnson, M. King, P. Minor, and C. Bailey National surveillance for asthma - United States, 1980-2004 MMWR Surveill Summ 56 2007 1 54
4. N. Pearce, N. Ait-Khaled, R. Beasley, J. Mallol, U. Keil, and E. Mitchell Worldwide trends in the prevalence of asthma symptoms: phase III of the International Study of Asthma and Allergies in Childhood (ISAAC) Thorax 62 2007 758 766
5. B.B. Obeng, F. Hartgers, D. Boakye, and M. Yazdanbakhsh Out of Africa: what can be learned from the studies of allergic disorders in Africa and Africans? Curr Opin Allergy Clin Immunol 8 2008 391 397
6. K.C. Barnes Genetic epidemiology of health disparities in allergy and clinical immunology J Allergy Clinical Immunol 117 2006 243 256
7. R.A. Kittles, and K.M. Weiss Race, ancestry, and genes: implications for defining disease risk Annu Rev Genomics Hum Genet 4 2003 33 67
8. H.S. Nelson, S.T. Weiss, E.R. Bleecker, S.W. Yancey, and P.M. Dorinsky The Salmeterol Multicenter Asthma Research Trial: a comparison of usual pharmacotherapy for asthma or usual pharmacotherapy plus salmeterol Chest 129 2006 15 26
9. H. Corvol, A. De Giacomo, C. Eng, M. Seibold, E. Ziv, and R. Chapela Genetic ancestry modifies pharmacogenetic gene-gene interaction for asthma Pharmacogenet Genomics 19 2009 489 496
10. S. Choudhry, E.G. Burchard, L.N. Borrell, H. Tang, I. Gomez, and M. Naqvi Ancestry-environment interactions and asthma risk among Puerto Ricans Am J Respir Crit Care Med 174 2006 1088 1093
11. C. Vergara, L. Caraballo, D. Mercado, S. Jimenez, W. Rojas, and N. Rafaels African ancestry is associated with risk of asthma and high total serum IgE in a population from the Caribbean Coast of Colombia Hum Genet 125 2009 565 579
12. R. Kumar, M.A. Seibold, M.C. Aldrich, L.K. Williams, A.P. Reiner, and L. Colangelo Genetic ancestry in lung-function predictions N Engl J Med 363 2010 321 330
13. W. Gould, E.L. Peterson, G. Karungi, A. Zoratti, J. Gaggin, and G. Toma Factors predicting inhaled corticosteroid responsiveness in African American patients with asthma J Allergy Clin Immunol 2010 1131 1138
14. C. Tian, R.M. Plenge, M. Ransom, A. Lee, P. Villoslada, and C. Selmi Analysis and application of European genetic substructure using 300 K SNP information PLoS Genet 4 2008 e4
15. T. Murray, T.H. Beaty, R.A. Mathias, N. Rafaels, A.V. Grant, and M.U. Faraque African and non-African admixture components in African Americans and an African Caribbean population Genet Epidemiol 34 2010 561 568