African and non-African admixture components in African Americans and an African Caribbean population

Genetic Epidemiology

Volumn 34, Issue 6, 2010, Pages 561-568

  Murray, Tanda ^a   Beaty, Terri H ^a   Mathias, Rasika A ^b   Rafaels, Nicholas ^b   Grant, Audrey Virginia ^c   Faruque, Mezbah U ^d   Watson, Harold R ^e   Ruczinski, Ingo ^a   Dunston, Georgia M ^d   Barnes, Kathleen C ^a,b  

^a JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c IMAGINE INSTITUTE   (France)

^d HOWARD UNIVERSITY COLLEGE OF MEDICINE   (United States)

^e UNIVERSITY OF THE WEST INDIES   (Jamaica)

Author keywords

Admixture; African americans; African ancestry; African caribbeans; Genetic distance

Indexed keywords

AFRICAN AMERICAN; AFRICAN CARIBBEAN; ARTICLE; ASTHMA; CONTROLLED STUDY; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC DISTANCE; GENETIC VARIABILITY; HUMAN; MAJOR CLINICAL STUDY; PLESIOMORPHY; RACE DIFFERENCE; SINGLE NUCLEOTIDE POLYMORPHISM;

AFRICAN AMERICANS; AFRICAN CONTINENTAL ANCESTRY GROUP; ALGORITHMS; BARBADOS; CARIBBEAN REGION; CASE-CONTROL STUDIES; EUROPEAN CONTINENTAL ANCESTRY GROUP; GENE FREQUENCY; GENETICS, POPULATION; GENOTYPE; HAPLOTYPES; HUMANS; MARKOV CHAINS; POLYMORPHISM, SINGLE NUCLEOTIDE; UNITED STATES;

EID: 77956242877     PISSN: 07410395     EISSN: 10982272     Source Type: Journal    
DOI: 10.1002/gepi.20512     Document Type: Article

References (20)

1. Barnes KC. 2006. Genetic epidemiology of health disparities in allergy and clinical immunology. J Allergy Clin Immunol 117:243-254.
2. Barnes KC, Neely JD, Duffy DL, Freidhoff LR, Breazeale DR, Schou C, Naidu RP, Levett PN, Renault B, Kucherlapati R, Iozzino S, Ehrlich E, Beaty TH, Marsh DG. 1996. Linkage of asthma and total serum IgE concentration to markers on chromosome 12q: evidence from Afro-Caribbean and Caucasian populations. Genomics 37:41-50.
3. Barrett JC, Fry B, Maller J, Daly MJ. 2005. Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics 21:263-265.
4. Benn-Torres J, Bonilla C, Robbins CM, Waterman L, Moses TY, Hernandez W, Santos ER, Bennett F, Aiken W, Tullock T, Coard K, Hennis A, Wu S, Nemesure B, Leske MC, Freeman V, Carpten J, Kittles RA. 2008. Admixture and population stratification in African Caribbean populations. Ann Hum Gen 72:90-98.
5. Chakraborty R, Kamboh MI, Nwankwo M, Ferrell RE. 1992. Caucasian genes in American blacks: new data. Am J Hum Genet 1:145-155.
6. Cheng CY, Kao WH, Patterson N, Tandon A, Haiman CA, Harris TB, Xing C, John EM, Ambrosone CB, Brancati FL, Coresh J, Press MF, Parekh RS, Klag MJ, Meoni LA, Hsueh WC, Fejerman L, Pawlikowska L, Freedman ML, Jandorf LH, Bandera EV, Ciupak GL, Nalls MA, Akylbekova EL, Orwoll ES, Leak TS, Miljkovic I, Li R, Ursin G, Bernstein L, Ardlie K, Taylor HA, Boerwinckle E, Zmuda JM, Henderson BE, Wilson JG, Reich D. 2009. Admixture mapping of 15,280 African Americans identifies obesity susceptibility loci on chromosomes 5 and X. PLoS Genet 5:e1000490.
7. Curtins PD. 1969. The Atlantic Slave Trade A Census. Madison: The Univeristy of Wisconsin Press.
8. Goncalves VF, Carvalho CMB, Bortolini MC, Bydlowski SP, Pena SDJ. 2008. The Phylogeography of African Brazilians. Hum Hered 65:23-32.
9. Marcella S, Miller JE. 2001. Racial differences in colorectal cancer mortality. The importance of stage and socioeconomic status. J Clin Epidemiol 54:359-366.
10. Mathias RA, Grant AV, Rafaels N, Hand T, Gao L, Vergara C, Tsai YJ, Yang M, Campbell M, Foster C, Gao P, Togias A, Hansel NN, Diette G, Adkinson NF, Liu MC, Faruque M, Dunston GM, Watson HR, Bracken MB, Hoh J, Maul P, Maul T, Jedlicka AE, Murray T, Hetmanski JB, Ashworth R, Ongaco CM, Hetrick KN, Doheny KF, Pugh EW, Rotimi CN, Ford J, Eng C, Burchard EG, Sleiman PM, Hakonarson H, Forno E, Raby BA, Weiss ST, Scott AF, Kabesch M, Liang L, Abecasis G, Moffatt MF, Cookson WO, Ruczinski I, Beaty TH, Barnes KC. 2010. A genome-wide association study on African-ancestry populations identifies novel asthma genes. Allergy Clin Immunol 125:336-346.
11. Parra EJ, Kittles RA, Argyropoulos G, Pfaff CL, Hiester K, Bonilla C, Sylvester N, Parrish-Gause D, Garvey WT, Jin L, McKeigue PM, Kamboh MI, Ferrell RE, Pollitzer WS, Shriver MD. 2001. Ancestral proportions and admixture dynamics in geographically defined African Americans living in South Carolina. Am J Phys Anthropol 114:18-29.
12. Parra EJ, Kittlles RA, Shriver MD. 2004. Implications of correlations between skin color and genetic ancestry for biomedical research. Nat Genet 36:S55-S60.
13. Patterson N, Price AL, Reich D. 2006. Population structure and eigenanalysis. PLOS Genet 2:2074-2093.
14. Pritchard JK, Stephens M, Donnelly P. 2002. Inference of population structure using multilocus genotyping data. Genetics 155:945-959.
15. Purcell S, Neale B, Todd-Brown K, Thomas L, Ferreira MAR, Bender D, Maller J, Sklar P, de Bakker PIW, Daly MJ, Sham PC. 2007. PLINK: a toolset for whole-genome association and population- based linkage analysis. Am J Hum Genet 81:559-575.
16. The International HapMap Consortium. 2003. The International HapMap Project. Nature 426:739.
17. Tishkoff SA, Reed FA, Friedlaender FR, Ehret C, Ranciaro A, Froment A, Hirbo JB, Awomoyi AA, Bodo JM, Doumbo O, Ibrahim M, Juma AT, Kotze MJ, Lema G, Moore JH, Mortensen H, Nyambo TB, Omar SA, Powell K, Pretorius GS, Smith MW, Thera MA, Wambebe C, Weber JL, Williams SM. 2009. The genetic structure and history of Africans and African Americans. Science 324:1035-1044.
18. Turakalov R, Easteal S. 2003. Number of Snp Loci needed to detect population structure. Hum Hered 55:37-45.
19. Wong MD, Ettner SL, Boscardin WJ, Shapiro MF. 2009. The contribution of cancer incidence, stage at diagnosis and survival to racial differences in years of life expectancy. J Gen Intern Med 24:475-481.
20. Ziv E, Burchard EG. 2003. Human population structure and genetic association studies. Pharmacogenomics 4:431-441.