Virus-cell and cell-cell fusion mediated by the HIV-1 envelope glycoprotein is inhibited by short gp41 N-terminal membrane-anchored peptides lacking the critical pocket domain

FASEB Journal

Volumn 24, Issue 11, 2010, Pages 4196-4202

  Wexler Cohen, Yael ^a   Ashkenazi, Avraham ^a   Viard, Mathias ^b,c   Blumenthal, Robert ^b   Shai, Yechiel ^a  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^b NATIONAL CANCER INSTITUTE   (United States)

^c SAIC FREDERICK INC   (United States)

Author keywords

HIV 1 entry inhibitor; Membrane fusion; Peptide membrane interaction; Viral envelope protein

Indexed keywords

ENVELOPE PROTEIN; FATTY ACID; GLYCOPROTEIN GP 41; LIPOPEPTIDE;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL FUSION; CIRCULAR DICHROISM; CONJUGATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; LENTIVIRINAE; NONHUMAN; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; VIRUS CELL INTERACTION; VIRUS INFECTIVITY;

AMINO ACID SEQUENCE; CELL FUSION; FATTY ACIDS; HIV ENVELOPE PROTEIN GP41; HIV FUSION INHIBITORS; HIV-1; HUMANS; JURKAT CELLS; MOLECULAR SEQUENCE DATA; PEPTIDES; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; VIRUS INTERNALIZATION;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 78649829342     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.09-151704     Document Type: Article

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