A switch from hBrm to Brg1 at IFNγ-activated sequences mediates the activation of human genes

Cell Research

Volumn 20, Issue 12, 2010, Pages 1345-1360

  Zhang, Ye ^a   Zhang, Yi ^a,b   Cheng, Mo Bin ^a   Zhang, Yan Jun ^a   Zhong, Xin ^a   Dai, Hui ^a   Yan, Li ^a   Wu, Ning Hua ^a   Shen, Yu Fei ^a  

^a PEKING UNION MEDICAL COLLEGE   (China)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Brg1; chromatin remodeling; hBrm; heat shock; IFN ; p300; Stat1

Indexed keywords

GAMMA INTERFERON; HEAT SHOCK PROTEIN 90; HELICASE; HISTONE ACETYLTRANSFERASE PCAF; NUCLEAR PROTEIN; P300-CBP-ASSOCIATED FACTOR; SMALL INTERFERING RNA; SMARCA2 PROTEIN, HUMAN; SMARCA4 PROTEIN, HUMAN; STAT1 PROTEIN; TRANSCRIPTION FACTOR;

ACETYLATION; AMINO ACID SEQUENCE; ARTICLE; CHROMATIN ASSEMBLY AND DISASSEMBLY; GENETICS; HUMAN; METABOLISM; MOLECULAR GENETICS; PHOSPHORYLATION; PROMOTER REGION; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TEMPERATURE; TRANSCRIPTION INITIATION;

ACETYLATION; AMINO ACID SEQUENCE; CHROMATIN ASSEMBLY AND DISASSEMBLY; DNA HELICASES; HSP90 HEAT-SHOCK PROTEINS; HUMANS; INTERFERON-GAMMA; MOLECULAR SEQUENCE DATA; NUCLEAR PROTEINS; P300-CBP TRANSCRIPTION FACTORS; PHOSPHORYLATION; PROMOTER REGIONS, GENETIC; RNA INTERFERENCE; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; STAT1 TRANSCRIPTION FACTOR; TEMPERATURE; TRANSCRIPTION FACTORS; TRANSCRIPTIONAL ACTIVATION;

EID: 78649827795     PISSN: 10010602     EISSN: 17487838     Source Type: Journal    
DOI: 10.1038/cr.2010.155     Document Type: Article

References (44)

1. de la Serna IL, Ohkawa Y, Imbalzano AN. Chromatin remodelling in mammalian differentiation: lessons from ATP-dependent remodellers. Nat Rev 2006; 7:461-473.
2. Flaus A, Owen-Hughes T. Mechanisms for ATP-dependent chromatin remodelling: farewell to the tuna-can octamer? Curr Opin Genet Dev 2004; 14:165-173.
3. Klochendler-Yeivin A, Muchardt C, Yaniv M. SWI/SNF chro-matin remodeling and cancer. Curr Opin Genet Dev 2002; 12:73-79.
4. Mohrmann L, Verrijzer CP. Composition and functional speci-fcity of SWI2/SNF2 class chromatin remodeling complexes. Biochim Biophys Acta 2005; 1681:59-73.
5. Chi T. A BAF-centred view of the immune system. Nat Rev Immunol 2004; 4:965-977.
6. Martens JA, Winston F. Recent advances in understanding chromatin remodeling by Swi/Snf complexes. Curr Opin Genet Dev 2003; 13:136-142.
7. Flowers S, Nagl NG, Jr, Beck GR, Jr, Moran E. Antagonistic roles for BRM and BRG1 SWI/SNF complexes in differentiation. J Biol Chem 2009; 284:10067-10075.
8. Nagl NG, Jr, Wang X, Patsialou A, Van Scoy M, Moran E. Distinct mammalian SWI/SNF chromatin remodeling complexes with opposing roles in cell-cycle control. EMBO J 2007; 26:752-763.
9. Strobeck MW, Reisman DN, Gunawardena RW, et al. Compensation of BRG-1 function by Brm: insight into the role of the core SWI-SNF subunits in retinoblastoma tumor suppressor signaling. J Biol Chem 2002; 277:4782-4789.
10. Kadam S, Emerson BM. Transcriptional specifcity of human SWI/SNF BRG1 and BRM chromatin remodeling complexes. Mol Cell 2003; 11:377-389.
11. Muchardt C, Yaniv M. When the SWI/SNF complex remodels..the cell cycle. Oncogene 2001; 20:3067-3075.
12. Bultman S, Gebuhr T, Yee D, et al. A Brg1 null mutation in the mouse reveals functional differences among mammalian SWI/SNF complexes. Mol Cell 2000; 6:1287-1295.
13. Bultman SJ, Gebuhr TC, Magnuson T. A Brg1 mutation that uncouples ATPase activity from chromatin remodeling reveals an essential role for SWI/SNF-related complexes in beta-globin expression and erythroid development. Genes Dev 2005; 19:2849-2861.
14. Wu JI, Lessard J, Crabtree GR. Understanding the words of chromatin regulation. Cell 2009; 136:200-206.
15. Lessard J, Wu JI, Ranish JA, et al. An essential switch in sub-unit composition of a chromatin remodeling complex during neural development. Neuron 2007; 55:201-215.
16. Cheng MB, Zhang Y, Zhong X, et al. Stat1 mediates an auto-regulation of hsp90beta gene in heat shock response. Cell Signal 2010; 22:1206-1213.
17. Levy DE, Darnell JE, Jr. Stats: transcriptional control and biological impact. Nat Rev Mol Cell Biol 2002; 3:651-662.
18. Platanias LC. Mechanisms of type-I-and type-II-interferon-mediated signalling. Nat Rev Immunol 2005; 5:375-386.
19. Schindler C, Levy DE, Decker T. JAK-STAT signaling: from interferons to cytokines. J Biol Chem 2007; 282:20059-20063.
20. Chen XS, Zhang Y, Wang JS, et al. Diverse effects of Stat1 on the regulation of hsp90alpha gene under heat shock. J Cell Biochem 2007; 102:1059-1066.
21. Giraud S, Hurlstone A, Avril S, Coqueret O. Implication of BRG1 and cdk9 in the STAT3-mediated activation of the p21waf1 gene. Oncogene 2004; 23:7391-7398.
22. Huang M, Qian F, Hu Y, et al. Chromatin-remodelling factor BRG1 selectively activates a subset of interferon-alpha-inducible genes. Nat Cell Biol 2002; 4:774-781.
23. Bourachot B, Yaniv M, Muchardt C. Growth inhibition by the mammalian SWI-SNF subunit Brm is regulated by acetyla-tion. EMBO J 2003; 22:6505-6515.
24. Holling TM, Schooten E, Langerak AW, van den Elsen PJ. Regulation of MHC class II expression in human T-cell malignancies. Blood 2004; 103:1438-1444.
25. Yoo AS, Crabtree GR. ATP-dependent chromatin remodeling in neural development. Curr Opin Neurobiol 2009; 19:120-126.
26. Wu JM, Xiao L, Cheng XK, et al. PKC epsilon is a unique regulator for hsp90 beta gene in heat shock response. J Biol Chem 2003; 278:51143-51149.
27. Mao X, Ren Z, Parker GN, et al. Structural bases of unphos-phorylated STAT1 association and receptor binding. Mol Cell 2005; 17:761-771.
28. Yang J, Stark GR. Roles of unphosphorylated STATs in signaling. Cell Res 2008; 18:443-451.
29. Sullivan EK, Weirich CS, Guyon JR, Sif S, Kingston RE. Transcriptional activation domains of human heat shock factor 1 recruit human SWI/SNF. Mol Cell Biol 2001; 21:5826-5837.
30. Qing Y, Stark GR. Alternative activation of STAT1 and STAT3 in response to interferon-gamma. J Biol Chem 2004; 279:41679-41685.
31. Calo V, Migliavacca M, Bazan V, et al. STAT proteins: from normal control of cellular events to tumorigenesis. J Cell Physiol 2003; 197:157-168.
32. Laherty CD, Yang WM, Sun JM, et al. Histone deacetylases associated with the mSin3 corepressor mediate mad transcrip-tional repression. Cell 1997; 89:349-356.
33. Silverstein RA, Ekwall K. Sin3: a fexible regulator of global gene expression and genome stability. Curr Genet 2005; 47:1-17.
34. van Oevelen C, Wang J, Asp P, et al. A role for mammalian Sin3 in permanent gene silencing. Mol Cell 2008; 32:359-370.
35. Hassan AH, Neely KE, Workman JL. Histone acetyltrans-ferase complexes stabilize swi/snf binding to promoter nu-cleosomes. Cell 2001; 104:817-827.
36. Gresh L, Bourachot B, Reimann A, et al. The SWI/SNF chromatin-remodeling complex subunit SNF5 is essential for hepatocyte differentiation. EMBO J 2005; 24:3313-3324.
37. Roberts CW, Galusha SA, McMenamin ME, Fletcher CD, Orkin SH. Haploinsuffciency of Snf5 (integrase interactor 1) predisposes to malignant rhabdoid tumors in mice. Proc Natl Acad Sci USA 2000; 97:13796-13800.
38. Memedula S, Belmont AS. Sequential recruitment of HAT and SWI/SNF components to condensed chromatin by VP16. Curr Biol 2003; 13:241-246.
39. Wang W, Xue Y, Zhou S, et al. Diversity and specialization of mammalian SWI/SNF complexes. Genes Dev 1996; 10:2117-2130.
40. Li ZY, Yang J, Gao X, et al. Sequential recruitment of PCAF and BRG1 contributes to myogenin activation in 12-O-tetradecanoylphorbol-13-acetate- induced early differentiation of rhabdomyosarcoma-derived cells. J Biol Chem 2007; 282:18872-18878.
41. Xiao L, Lang W. A dominant role for the c-Jun NH2-terminal kinase in oncogenic ras-induced morphologic transformation of human lung carcinoma cells. Cancer Res 2000; 60:400-408.
42. Kuo MH, Allis CD. In vivo cross-linking and immunoprecipi-tation for studying dynamic Protein:DNA associations in a chromatin environment. Methods 1999; 19:425-433.
43. Zhang Y, Wang JS, Chen LL, et al. Repression of hsp90beta gene by p53 in UV irradiation-induced apoptosis of Jurkat cells. J Biol Chem 2004; 279:42545-42551.
44. Tahiliani M, Mei P, Fang R, et al. The histone H3K4 dem-ethylase SMCX links REST target genes to X-linked mental retardation. Nature 2007; 447:601-605.