Continuation of cinacalcet immediately after renal transplantation: A prospective cohort study

Clinical Nephrology

Volumn 74, Issue 6, 2010, Pages 433-439

  Aalten, J ^a   Wetzels, J F M ^a   Hoitsma, A J ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Cinacalcet; Hypercalcemia; Hyperparathyroidism; Renal transplantation; Safety

Indexed keywords

CALCIUM CARBONATE; CINACALCET; COLECALCIFEROL DERIVATIVE; CYCLOSPORIN; FUROSEMIDE; METHYLPREDNISOLONE; MYCOPHENOLIC ACID; PAMIDRONIC ACID; PARATHYROID HORMONE; PHOSPHATE; PREDNISOLONE; SODIUM CHLORIDE; TACROLIMUS;

ACUTE GRAFT REJECTION; ADULT; ARTICLE; CALCIUM BLOOD LEVEL; CLINICAL ARTICLE; COHORT ANALYSIS; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG DOSE INCREASE; DRUG DOSE REDUCTION; DRUG DOSE TITRATION; DRUG MEGADOSE; FEMALE; FOLLOW UP; GASTROINTESTINAL DISEASE; GRAFT RECIPIENT; GRAFT REJECTION; HUMAN; HYPERCALCEMIA; HYPOCALCEMIA; HYPOPHOSPHATEMIA; KIDNEY FUNCTION; KIDNEY TRANSPLANTATION; MALE; OPTIMAL DRUG DOSE; POSTOPERATIVE PERIOD; PROSPECTIVE STUDY; SECONDARY HYPERPARATHYROIDISM;

EID: 78649827375     PISSN: 03010430     EISSN: None     Source Type: Journal    
DOI: 10.5414/cnp74433     Document Type: Article

References (19)

1. Evenepoel P, Claes K, Kuypers D, Maes B, Bammens B, Vanrenterghem Y. Natural history of parathyroid function and calcium metabolism after kidney transplantation: a single-centre study. Nephrol Dial Transplant. 2004; 19: 1281-1287.
2. Evenepoel P, Van Den Bergh B, Naesens M, De JH, Bammens B, Claes K et al. Calcium metabolism in the early posttransplantation period. Clin J Am Soc Nephrol. 2009; 4: 665-672.
3. Boom H, Mallat MJ, de Fijter JW, Paul LC, Bruijn JA, van Es LA. Calcium levels as a risk factor for delayed graft function. Transplantation. 2004; 77: 868-873.
4. Gwinner W, Suppa S, Mengel M, Hoy L, Kreipe HH, Haller H et al. Early calcification of renal allografts detected by protocol biopsies: causes and clinical implications. Am J Transplant. 2005; 5: 1934-1941.
5. Kasiske BL, Cangro CB, Hariharan S, Hricik DE, Kerman RH, Roth D et al. The evaluation of renal transplantation candidates: clinical practice guidelines. Am J Transplant. 2001; 1 (Suppl): 3-95.
6. K/DOQI. clinical practice guidelines for bone metabolism and disease in chronic kidney disease. Am J Kidney Dis. 2003; 42 (Suppl): 1-201.
7. Cunningham J, Danese M, Olson K, Klassen P, Chertow GM. Effects of the calcimimetic cinacalcet HCl on cardiovascular disease, fracture, and health-related quality of life in secondary hyperparathyroidism. Kidney Int. 2005; 68: 1793-1800.
8. Block GA, Martin KJ, de Francisco AL, Turner SA, Avram MM, Suranyi MG et al. Cinacalcet for secondary hyperparathyroidism in patients receiving hemodialysis. N Engl J Med. 2004; 350: 1516-1525.
9. Lindberg JS, Culleton B, WongG, Borah MF, Clark RV, Shapiro WB et al. Cinacalcet HCl, an oral calcimimetic agent for the treatment of secondary hyperparathyroidism in hemodialysis and peritoneal dialysis: a randomized, double-blind, multicenter study. J Am Soc Nephrol. 2005; 16: 800-807.
10. Kruse A, Eisenberger U, Frey F et al. The calcimimetic cinacalcet normalizes serum calcium in renal transplant patients with persistent hyperparathyroidism. Nephrol Dial Transplant. 2005; 20: 1311-1314.
11. Leca N, Laftavi M, Gundroo A, Kohli R, Min I, Karam J et al. Early and severe hyperparathyroidism associated with hypercalcemia after renal transplant treated with cinacalcet. Am J Transplant. 2006; 6: 2391-2395.
12. Serra A, Schwarz A, Wick F et al. Successful treatment of hypercalcaemia with cinacalcet in renal transplant recipients with persistent hyperparathyroidism. Nephrol Dial Transplant. 2005; 20: 1315-1319.
13. Szwarc I, Argiles A, Garrigue V et al. Cinacalcet chloride is efficient and safe in renal transplant recipients with posttransplant hyperparathyroidism. Transplantation. 2007; 82: 675-680.
14. Serra AL, Braun SC, Starke A, Savoca R, Hersberger M, Russmann S et al. Pharmacokinetics and pharmacodynamics of cinacalcet in patients with hyperparathyroidism after renal transplantation. Am J Transplant. 2008; 8: 803-810.
15. Torregrosa JV, Bergua C, Martinez de Osaba MJ, Oppenheimer F, Campistol JM. Evolution of secondary hyperparathyroidism after kidney transplantation in patients receiving cinacalcet on dialysis. Transplant Proc. 2009; 41: 2396-2398.
16. Falck P, Vethe NT, Asberg A, Midtvedt K, Bergan S, Reubsaet JL et al. Cinacalcet's effect on the pharmacokinetics of tacrolimus, cyclosporine and mycophenolate in renal transplant recipients. Nephrol Dial Transplant 2008 March; 23: 1048-1053.
17. Kamar N, Gennero I, Spataru L, Esposito L, Guitard J, Lavayssiere L et al. Pharmacodynamic effects of cinacalcet after kidney transplantation: once- versus twice-daily dose. Nephrol Dial Transplant. 2008; 23: 3720-3726.
18. Kruse AE, Eisenberger U, Frey FJ, Mohaupt MG. Effect of cinacalcet cessation in renal transplant recipients with persistent hyperparathyroidism. Nephrol Dial Transplant. 2007; 22: 2362-2365.
19. Meola M, Petrucci I, Barsotti G. Long-term treatment with cinacalcet and conventional therapy reduces parathyroid hyperplasia in severe secondary hyperparathyroidism. Nephrol Dial Transplant. 2009; 24: 982-989.