Rapid and sensitive LC-MS/MS method for determination of felbamate in mouse plasma and tissues and human plasma

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 878, Issue 32, 2010, Pages 3432-3436

  Hansen, Ryan J ^a   Samber, Bradley J ^a   Gustafson, Daniel L ^a  

^a Veterinary Dentistry and Oral Surgery   (United States)

Author keywords

Antiepileptic drug; Felbamate; Human plasma; LC MS MS; Liquid chromatography tandem mass spectrometry

Indexed keywords

ANTIEPILEPTIC DRUGS; FELBAMATE; HUMAN PLASMAS; LC-MS/MS; LIQUID CHROMATOGRAPHY TANDEM MASS SPECTROMETRY;

ACETONITRILE; CALIBRATION; CHROMATOGRAPHY; HIGH PRESSURE LIQUID CHROMATOGRAPHY; HISTOLOGY; LIQUIDS; MASS SPECTROMETRY; PLASMA (HUMAN); STANDARDS; TISSUE;

PLASMAS;

ACETONITRILE; CARISOPRODOL; FELBAMATE; PHENYL GROUP; PROTEIN;

ACCURACY; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; BLOOD; BLOOD SAMPLING; BRAIN TISSUE; CALIBRATION; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG STABILITY; HUMAN; LIQUID CHROMATOGRAPHY; LIVER; MAXIMUM PLASMA CONCENTRATION; MOUSE; NONHUMAN; PHASE TRANSITION; PRECIPITATION; PRIORITY JOURNAL; PROTEIN PRECIPITATION; REACTOR MONITORING; TANDEM MASS SPECTROMETRY; TIME TO MAXIMUM PLASMA CONCENTRATION; TISSUE HOMOGENATE;

ANIMALS; ANTICONVULSANTS; BRAIN CHEMISTRY; CARISOPRODOL; CHROMATOGRAPHY, LIQUID; HUMANS; LEAST-SQUARES ANALYSIS; LIVER; MICE; PHENYLCARBAMATES; PROPYLENE GLYCOLS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; TANDEM MASS SPECTROMETRY;

EID: 78649814005     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2010.10.006     Document Type: Article

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