High performance liquid chromatography assay with ultraviolet detection for moxifloxacin: Validation and application to a pharmacokinetic study in Chinese volunteers

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 878, Issue 32, 2010, Pages 3437-3441

  Xu, Yu Hong ^a   Li, Dong ^b   Liu, Xin Yu ^a   Li, Yu Zhen ^a   Lu, Jian ^c  

^a GUANGDONG MEDICAL UNIVERSITY   (China)

^b SHENZHEN PEOPLE'S HOSPITAL   (China)

^c SHENZHEN THIRD PEOPLE S HOSPITAL   (China)

Author keywords

HPLC UV; Moxifloxacin; Pharmacokinetics; Validation

Indexed keywords

CALIBRATION CURVES; CONCENTRATION RANGES; CORRELATION COEFFICIENT; EXTRACTION YIELD; HPLC-UV; HUMAN PLASMAS; ISOCRATIC MOBILE PHASE; LIQUID-LIQUID EXTRACTION; MOXIFLOXACIN; PHARMACOKINETIC STUDIES; SINGLE-STEP; ULTRA VIOLET DETECTION; VALIDATION;

CHROMATOGRAPHY; DICHLOROMETHANE; LIQUIDS; PHARMACOKINETICS; SOLVENT EXTRACTION;

HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

DICHLOROMETHANE; MOXIFLOXACIN;

ACCURACY; ADULT; AREA UNDER THE CURVE; ARTICLE; BLOOD SAMPLING; CALIBRATION; CHINESE; COLUMN CHROMATOGRAPHY; CONTROLLED STUDY; CORRELATION COEFFICIENT; DRUG BLOOD LEVEL; DRUG DETERMINATION; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN EXPERIMENT; LIQUID LIQUID EXTRACTION; MALE; MAXIMUM PLASMA CONCENTRATION; NORMAL HUMAN; PHARMACOLOGICAL PARAMETERS; PRIORITY JOURNAL; SENSITIVITY AND SPECIFICITY; SEPARATION TECHNIQUE; TIME TO MAXIMUM PLASMA CONCENTRATION; ULTRAVIOLET RADIATION;

ADULT; AZA COMPOUNDS; CHINA; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG STABILITY; FEMALE; HUMANS; LEAST-SQUARES ANALYSIS; MALE; QUINOLINES; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SPECTROPHOTOMETRY, ULTRAVIOLET; YOUNG ADULT;

EID: 78649808084     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2010.10.024     Document Type: Article

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