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Volumn 151, Issue 12, 2010, Pages 5730-5740

Glucocorticoid-induced impairment of mammary gland involution is associated with STAT5 and STAT3 signaling modulation

Author keywords

[No Author keywords available]

Indexed keywords

BETA CASEIN; DEXAMETHASONE; GLUCOCORTICOID; PROLACTIN; STAT3 PROTEIN; STAT5 PROTEIN;

EID: 78649805673     PISSN: 00137227     EISSN: 00137227     Source Type: Journal    
DOI: 10.1210/en.2010-0517     Document Type: Article
Times cited : (32)

References (64)
  • 1
    • 0035489712 scopus 로고    scopus 로고
    • Signaling pathways in mammary gland development
    • Hennighausen L, Robinson GW 2001 Signaling pathways in mammary gland development. Dev Cell 1:467-475
    • (2001) Dev Cell , vol.1 , pp. 467-475
    • Hennighausen, L.1    Robinson, G.W.2
  • 2
    • 0024377789 scopus 로고
    • Cell death by apoptosis during involution of the lactating breast in mice and rats
    • Walker NI, Bennett RE, Kerr JF 1989 Cell death by apoptosis during involution of the lactating breast in mice and rats. Am J Anat 185: 19-32
    • (1989) Am J Anat , vol.185 , pp. 19-32
    • Walker, N.I.1    Bennett, R.E.2    Kerr, J.F.3
  • 3
    • 0026773069 scopus 로고
    • Apoptotic cell death and tissue remodelling during mouse mammary gland involution
    • Strange R, Li F, Saurer S, Burkhardt A, Friis RR 1992 Apoptotic cell death and tissue remodelling during mouse mammary gland involution. Development 115:49-58
    • (1992) Development , vol.115 , pp. 49-58
    • Strange, R.1    Li, F.2    Saurer, S.3    Burkhardt, A.4    Friis, R.R.5
  • 4
    • 0028283503 scopus 로고
    • Molecular mechanisms of action of steroid/thyroid receptor superfamily members
    • Tsai MJ, O'Malley BW 1994 Molecular mechanisms of action of steroid/thyroid receptor superfamily members. Annu Rev Biochem 63:451-486
    • (1994) Annu Rev Biochem , vol.63 , pp. 451-486
    • Tsai, M.J.1    O'Malley, B.W.2
  • 5
    • 0027993605 scopus 로고
    • Prolactin induces phosphorylation of Tyr694 of Stat5 (MGF), a prerequisite for DNA binding and induction of transcription
    • Gouilleux F, Wakao H, Mundt M, Groner B 1994 Prolactin induces phosphorylation of Tyr694 of Stat5 (MGF), a prerequisite for DNA binding and induction of transcription. EMBO J 13:4361-4369
    • (1994) EMBO J , vol.13 , pp. 4361-4369
    • Gouilleux, F.1    Wakao, H.2    Mundt, M.3    Groner, B.4
  • 7
    • 67349162522 scopus 로고    scopus 로고
    • Dexamethasone inhibits camptothecin-induced apoptosis in C6-glioma via activation of Stat5/Bcl-xL pathway
    • Qian YH, Xiao Q, Chen H, Xu J 2009 Dexamethasone inhibits camptothecin-induced apoptosis in C6-glioma via activation of Stat5/Bcl-xL pathway. Biochim Biophys Acta 1793:764-771
    • (2009) Biochim Biophys Acta , vol.1793 , pp. 764-771
    • Qian, Y.H.1    Xiao, Q.2    Chen, H.3    Xu, J.4
  • 8
    • 0142091544 scopus 로고    scopus 로고
    • STAT3- dependent enhanceosome assembly and disassembly: Synergy with GR for full transcriptional increase of the α2-macroglobulin gene
    • Lerner L, Henriksen MA, Zhang X, Darnell Jr JE 2003 STAT3- dependent enhanceosome assembly and disassembly: synergy with GR for full transcriptional increase of the α2-macroglobulin gene. Genes Dev 17:2564-2577
    • (2003) Genes Dev , vol.17 , pp. 2564-2577
    • Lerner, L.1    Henriksen, M.A.2    Zhang, X.3    Darnell Jr., J.E.4
  • 9
    • 0032934069 scopus 로고    scopus 로고
    • Glucocorticoid receptor/ signal transducer and activator of transcription 5 (STAT5) interactions enhance STAT5 activation by prolonging STAT5 DNA binding and tyrosine phosphorylation
    • Wyszomierski SL, Yeh J, Rosen JM 1999 Glucocorticoid receptor/ signal transducer and activator of transcription 5 (STAT5) interactions enhance STAT5 activation by prolonging STAT5 DNA binding and tyrosine phosphorylation. Mol Endocrinol 13:330-343
    • (1999) Mol Endocrinol , vol.13 , pp. 330-343
    • Wyszomierski, S.L.1    Yeh, J.2    Rosen, J.M.3
  • 10
    • 0030667790 scopus 로고    scopus 로고
    • STAT3 acts as a co-activator of glucocorticoid receptor signaling
    • Zhang Z, Jones S, Hagood JS, Fuentes NL, Fuller GM 1997 STAT3 acts as a co-activator of glucocorticoid receptor signaling. J Biol Chem 272:30607-30610
    • (1997) J Biol Chem , vol.272 , pp. 30607-30610
    • Zhang, Z.1    Jones, S.2    Hagood, J.S.3    Fuentes, N.L.4    Fuller, G.M.5
  • 11
    • 0031899361 scopus 로고    scopus 로고
    • Characterization of Stat5a and Stat5b homodimers and heterodimers and their association with the glucocortiocoid receptor in mammary cells
    • Cella N, Groner B, Hynes NE 1998 Characterization of Stat5a and Stat5b homodimers and heterodimers and their association with the glucocortiocoid receptor in mammary cells. Mol Cell Biol 18:1783-1792
    • (1998) Mol Cell Biol , vol.18 , pp. 1783-1792
    • Cella, N.1    Groner, B.2    Hynes, N.E.3
  • 12
    • 63249107952 scopus 로고    scopus 로고
    • Interferon-α inhibits glucocorticoid receptor-mediated gene transcription via STAT5 activation in mouse HT22 cells
    • Hu F, Pace TW, Miller AH 2009 Interferon-α inhibits glucocorticoid receptor-mediated gene transcription via STAT5 activation in mouse HT22 cells. Brain Behav Immun 23:455-463
    • (2009) Brain Behav Immun , vol.23 , pp. 455-463
    • Hu, F.1    Pace, T.W.2    Miller, A.H.3
  • 13
    • 0028231721 scopus 로고
    • Hormonal regulation of transcription factor activity in mammary epithelial cells
    • Groner B, Altiok S, Meier V 1994 Hormonal regulation of transcription factor activity in mammary epithelial cells. Mol Cell Endocrinol 100:109-114
    • (1994) Mol Cell Endocrinol , vol.100 , pp. 109-114
    • Groner, B.1    Altiok, S.2    Meier, V.3
  • 14
    • 0031434176 scopus 로고    scopus 로고
    • Mechanism of interaction between the glucocorticoid receptor and Stat5: Role of DNA-binding
    • Lechner J, Welte T, Doppler W 1997 Mechanism of interaction between the glucocorticoid receptor and Stat5: role of DNA-binding. Immunobiology 198:112-123
    • (1997) Immunobiology , vol.198 , pp. 112-123
    • Lechner, J.1    Welte, T.2    Doppler, W.3
  • 15
    • 0029851231 scopus 로고    scopus 로고
    • Functional interactions between Stat5 and the glucocorticoid receptor
    • Stöcklin E, Wissler M, Gouilleux F, Groner B 1996 Functional interactions between Stat5 and the glucocorticoid receptor. Nature 383:726-728
    • (1996) Nature , vol.383 , pp. 726-728
    • Stöcklin, E.1    Wissler, M.2    Gouilleux, F.3    Groner, B.4
  • 16
    • 4344603767 scopus 로고    scopus 로고
    • Stat3 enhances transactivation of steroid hormone receptors
    • De Miguel F, Lee SO, Onate SA, Gao AC 2003 Stat3 enhances transactivation of steroid hormone receptors. Nucl Recept 1:3
    • (2003) Nucl Recept , vol.1 , pp. 3
    • De Miguel, F.1    Lee, S.O.2    Onate, S.A.3    Gao, A.C.4
  • 19
    • 0036720557 scopus 로고    scopus 로고
    • Deletion of Stat3 blocks mammary gland involution and extends functional competence of the secretory epithelium in the absence of lactogenic stimuli
    • Humphreys RC, Bierie B, Zhao L, Raz R, Levy D, Hennighausen L 2002 Deletion of Stat3 blocks mammary gland involution and extends functional competence of the secretory epithelium in the absence of lactogenic stimuli. Endocrinology 143:3641-3650
    • (2002) Endocrinology , vol.143 , pp. 3641-3650
    • Humphreys, R.C.1    Bierie, B.2    Zhao, L.3    Raz, R.4    Levy, D.5    Hennighausen, L.6
  • 20
  • 21
    • 0029906982 scopus 로고    scopus 로고
    • Activation of Stat5a and Stat5b by tyrosine phosphorylation is tightly linked to mammary gland differentiation
    • Liu X, Robinson GW, Hennighausen L 1996 Activation of Stat5a and Stat5b by tyrosine phosphorylation is tightly linked to mammary gland differentiation. Mol Endocrinol 10:1496-1506
    • (1996) Mol Endocrinol , vol.10 , pp. 1496-1506
    • Liu, X.1    Robinson, G.W.2    Hennighausen, L.3
  • 23
    • 41149149301 scopus 로고    scopus 로고
    • Interpretation of cytokine signaling through the transcription factors STAT5A and STAT5B
    • Hennighausen L, Robinson GW 2008 Interpretation of cytokine signaling through the transcription factors STAT5A and STAT5B. Genes Dev 22:711-721
    • (2008) Genes Dev , vol.22 , pp. 711-721
    • Hennighausen, L.1    Robinson, G.W.2
  • 25
    • 0034652613 scopus 로고    scopus 로고
    • The glucocorticoid receptor mediates a survival signal in human mammary epithelial cells
    • Moran TJ, Gray S, Mikosz CA, Conzen SD 2000 The glucocorticoid receptor mediates a survival signal in human mammary epithelial cells. Cancer Res 60:867-872
    • (2000) Cancer Res , vol.60 , pp. 867-872
    • Moran, T.J.1    Gray, S.2    Mikosz, C.A.3    Conzen, S.D.4
  • 26
    • 0017966251 scopus 로고
    • Glucocorticoids in mammary secretions and blood serum during reproduction and lactation and distributions of glucocorticoids, progesterone, and estrogens in fractions of milk
    • Schwalm JW, Tucker HA 1978 Glucocorticoids in mammary secretions and blood serum during reproduction and lactation and distributions of glucocorticoids, progesterone, and estrogens in fractions of milk. J Dairy Sci 61:550-560
    • (1978) J Dairy Sci , vol.61 , pp. 550-560
    • Schwalm, J.W.1    Tucker, H.A.2
  • 27
    • 0030846576 scopus 로고    scopus 로고
    • Promoter-dependent synergy between glucocorticoid receptor and Stat5 in the activation of beta-casein gene transcription
    • Lechner J, Welte T, Tomasi JK, Bruno P, Cairns C, Gustafsson J, Doppler W 1997 Promoter-dependent synergy between glucocorticoid receptor and Stat5 in the activation of beta-casein gene transcription. J Biol Chem 272:20954-20960
    • (1997) J Biol Chem , vol.272 , pp. 20954-20960
    • Lechner, J.1    Welte, T.2    Tomasi, J.K.3    Bruno, P.4    Cairns, C.5    Gustafsson, J.6    Doppler, W.7
  • 28
    • 0022227647 scopus 로고
    • Prolactin-inducible proteins in human breast cancer cells
    • Shiu RP, Iwasiow BM 1985 Prolactin-inducible proteins in human breast cancer cells. J Biol Chem 260:11307-11313
    • (1985) J Biol Chem , vol.260 , pp. 11307-11313
    • Shiu, R.P.1    Iwasiow, B.M.2
  • 29
    • 0024512152 scopus 로고
    • Gross cystic disease fluid protein-15 as a marker for breast cancer: Immunohistochemical analysis of 690 human neoplasms and comparison with α-lactalbumin
    • Wick MR, Lillemoe TJ, Copland GT, Swanson PE, Manivel JC, Kiang DT 1989 Gross cystic disease fluid protein-15 as a marker for breast cancer: immunohistochemical analysis of 690 human neoplasms and comparison with α-lactalbumin. Hum Pathol 20:281-287
    • (1989) Hum Pathol , vol.20 , pp. 281-287
    • Wick, M.R.1    Lillemoe, T.J.2    Copland, G.T.3    Swanson, P.E.4    Manivel, J.C.5    Kiang, D.T.6
  • 30
    • 0028572466 scopus 로고
    • PIP/ GCDFP-15 gene expression and apocrine differentiation in carcinomas of the breast
    • Pagani A, Sapino A, Eusebi V, Bergnolo P, Bussolati G 1994 PIP/ GCDFP-15 gene expression and apocrine differentiation in carcinomas of the breast. Virchows Arch 425:459-465
    • (1994) Virchows Arch , vol.425 , pp. 459-465
    • Pagani, A.1    Sapino, A.2    Eusebi, V.3    Bergnolo, P.4    Bussolati, G.5
  • 31
    • 0030030021 scopus 로고    scopus 로고
    • Two distinct phases of apoptosis in mammary gland involution: Proteinase-independent and -dependent pathways
    • Lund LR, Romer J, Thomasset N, Solberg H, Pyke C, Bissell MJ, Dano K, Werb Z 1996 Two distinct phases of apoptosis in mammary gland involution: proteinase-independent and -dependent pathways. Development 122:181-193
    • (1996) Development , vol.122 , pp. 181-193
    • Lund, L.R.1    Romer, J.2    Thomasset, N.3    Solberg, H.4    Pyke, C.5    Bissell, M.J.6    Dano, K.7    Werb, Z.8
  • 32
    • 0031009363 scopus 로고    scopus 로고
    • Milk accumulation triggers apoptosis of mammary epithelial cells
    • Marti A, Feng Z, Altermatt HJ, Jaggi R 1997 Milk accumulation triggers apoptosis of mammary epithelial cells. Eur J Cell Biol 73: 158-165
    • (1997) Eur J Cell Biol , vol.73 , pp. 158-165
    • Marti, A.1    Feng, Z.2    Altermatt, H.J.3    Jaggi, R.4
  • 34
    • 34247551104 scopus 로고    scopus 로고
    • Involution: Apoptosis and tissue remodelling that convert the mammary gland from milk factory to a quiescent organ
    • Watson CJ 2006 Involution: apoptosis and tissue remodelling that convert the mammary gland from milk factory to a quiescent organ. Breast Cancer Res 8:203
    • (2006) Breast Cancer Res , vol.8 , pp. 203
    • Watson, C.J.1
  • 36
    • 0042977593 scopus 로고    scopus 로고
    • A dual, non-redundant, role for LIF as a regulator of development and STAT3-mediated cell death in mammary gland
    • Kritikou EA, Sharkey A, Abell K, Came PJ, Anderson E, Clarkson RW, Watson CJ 2003 A dual, non-redundant, role for LIF as a regulator of development and STAT3-mediated cell death in mammary gland. Development 130:3459-3468
    • (2003) Development , vol.130 , pp. 3459-3468
    • Kritikou, E.A.1    Sharkey, A.2    Abell, K.3    Came, P.J.4    Anderson, E.5    Clarkson, R.W.6    Watson, C.J.7
  • 38
    • 0032713453 scopus 로고    scopus 로고
    • Signal transducer and activator of transcription 5a influences mammary epithelial cell survival and tumorigenesis
    • Humphreys RC, Hennighausen L 1999 Signal transducer and activator of transcription 5a influences mammary epithelial cell survival and tumorigenesis. Cell Growth Differ 10:685-694
    • (1999) Cell Growth Differ , vol.10 , pp. 685-694
    • Humphreys, R.C.1    Hennighausen, L.2
  • 39
    • 0030605006 scopus 로고    scopus 로고
    • Differential activation of STATs 3 and 5 during mammary gland development
    • Philp JA, Burdon TG, Watson CJ 1996 Differential activation of STATs 3 and 5 during mammary gland development. FEBS Lett 396:77-80
    • (1996) FEBS Lett , vol.396 , pp. 77-80
    • Philp, J.A.1    Burdon, T.G.2    Watson, C.J.3
  • 40
    • 33344462686 scopus 로고    scopus 로고
    • The genes induced by signal transducer and activators of transcription (STAT)3 and STAT5 in mammary epithelial cells define the roles of these STATs in mammary development
    • Clarkson RW, Boland MP, Kritikou EA, Lee JM, Freeman TC, Tiffen PG, Watson CJ 2006 The genes induced by signal transducer and activators of transcription (STAT)3 and STAT5 in mammary epithelial cells define the roles of these STATs in mammary development. Mol Endocrinol 20:675-685
    • (2006) Mol Endocrinol , vol.20 , pp. 675-685
    • Clarkson, R.W.1    Boland, M.P.2    Kritikou, E.A.3    Lee, J.M.4    Freeman, T.C.5    Tiffen, P.G.6    Watson, C.J.7
  • 41
    • 4444268818 scopus 로고    scopus 로고
    • Inactivation of Stat5 in mouse mammary epithelium during pregnancy reveals distinct functions in cell proliferation, survival, and differentiation
    • Cui Y, Riedlinger G, Miyoshi K, Tang W, Li C, Deng CX, Robinson GW, Hennighausen L 2004 Inactivation of Stat5 in mouse mammary epithelium during pregnancy reveals distinct functions in cell proliferation, survival, and differentiation. Mol Cell Biol 24:8037-8047
    • (2004) Mol Cell Biol , vol.24 , pp. 8037-8047
    • Cui, Y.1    Riedlinger, G.2    Miyoshi, K.3    Tang, W.4    Li, C.5    Deng, C.X.6    Robinson, G.W.7    Hennighausen, L.8
  • 42
    • 0345700700 scopus 로고    scopus 로고
    • Overexpression and forced activation of stat5 in mammary gland of transgenic mice promotes cellular proliferation, enhances differentiation, and delays postlactational apoptosis
    • Iavnilovitch E, Groner B, Barash I 2002 Overexpression and forced activation of stat5 in mammary gland of transgenic mice promotes cellular proliferation, enhances differentiation, and delays postlactational apoptosis. Mol Cancer Res 1:32-47
    • (2002) Mol Cancer Res , vol.1 , pp. 32-47
    • Iavnilovitch, E.1    Groner, B.2    Barash, I.3
  • 44
    • 0028784787 scopus 로고
    • Glucocorticoid and progesterone inhibit involution and programmed cell death in the mouse mammary gland
    • Feng Z, Marti A, Jehn B, Altermatt HJ, Chicaiza G, Jaggi R 1995 Glucocorticoid and progesterone inhibit involution and programmed cell death in the mouse mammary gland. J Cell Biol 131: 1095-1103
    • (1995) J Cell Biol , vol.131 , pp. 1095-1103
    • Feng, Z.1    Marti, A.2    Jehn, B.3    Altermatt, H.J.4    Chicaiza, G.5    Jaggi, R.6
  • 45
    • 36649008781 scopus 로고    scopus 로고
    • The role of glucocorticoids in secretory activation and milk secretion, a historical perspective
    • Casey TM, Plaut K 2007 The role of glucocorticoids in secretory activation and milk secretion, a historical perspective. J Mammary Gland Biol Neoplasia 12:293-304
    • (2007) J Mammary Gland Biol Neoplasia , vol.12 , pp. 293-304
    • Casey, T.M.1    Plaut, K.2
  • 46
    • 0035992837 scopus 로고    scopus 로고
    • Effects of a gonadotropin-releasing hormone agonist on rat ovarian follicle apoptosis: Regulation by epidermal growth factor and the expression of Bcl-2-related genes
    • Parborell F, Pecci A, Gonzalez O, Vitale A, Tesone M 2002 Effects of a gonadotropin-releasing hormone agonist on rat ovarian follicle apoptosis: regulation by epidermal growth factor and the expression of Bcl-2-related genes. Biol Reprod 67:481-486
    • (2002) Biol Reprod , vol.67 , pp. 481-486
    • Parborell, F.1    Pecci, A.2    Gonzalez, O.3    Vitale, A.4    Tesone, M.5
  • 47
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford MM 1976 A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248-254
    • (1976) Anal Biochem , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 48
    • 0023066651 scopus 로고
    • Intracellular receptor concentration limits glucocorticoid-dependent enhancer activity
    • Vanderbilt JN, Miesfeld R, Maler BA, Yamamoto KR 1987 Intracellular receptor concentration limits glucocorticoid-dependent enhancer activity. Mol Endocrinol 1:68-74
    • (1987) Mol Endocrinol , vol.1 , pp. 68-74
    • Vanderbilt, J.N.1    Miesfeld, R.2    Maler, B.A.3    Yamamoto, K.R.4
  • 49
    • 0022760230 scopus 로고
    • Glucocorticoid receptor of rat mammary gland during pregnancy and lactation
    • Alexandrová M 1986 Glucocorticoid receptor of rat mammary gland during pregnancy and lactation. Endocrinol Exp 20:293-300
    • (1986) Endocrinol Exp , vol.20 , pp. 293-300
    • Alexandrová, M.1
  • 50
    • 52949083209 scopus 로고    scopus 로고
    • Prolactin and ErbB4/HER4 signaling interact via Janus kinase 2 to induce mammary epithelial cell gene expression differentiation
    • Muraoka-Cook RS, Sandahl M, Hunter D, Miraglia L, Earp 3rd HS 2008 Prolactin and ErbB4/HER4 signaling interact via Janus kinase 2 to induce mammary epithelial cell gene expression differentiation. Mol Endocrinol 22:2307-2321
    • (2008) Mol Endocrinol , vol.22 , pp. 2307-2321
    • Muraoka-Cook, R.S.1    Sandahl, M.2    Hunter, D.3    Miraglia, L.4    Earp III, H.S.5
  • 51
    • 38949105121 scopus 로고    scopus 로고
    • Co-overexpression of Janus kinase 2 and signal transducer and activator of transcription 5a promotes differentiation of mammary cancer cells through reversal of epithelial-mesenchymal transition
    • Sultan AS, Brim H, Sherif ZA 2008 Co-overexpression of Janus kinase 2 and signal transducer and activator of transcription 5a promotes differentiation of mammary cancer cells through reversal of epithelial-mesenchymal transition. Cancer Sci 99:272-279
    • (2008) Cancer Sci , vol.99 , pp. 272-279
    • Sultan, A.S.1    Brim, H.2    Sherif, Z.A.3
  • 54
    • 9544229695 scopus 로고    scopus 로고
    • Glucocorticoid down-regulation of rat glucocorticoid receptor does not involve differential promoter regulation
    • Freeman AI, Munn HL, Lyons V, Dammermann A, Seckl JR, Chapman KE 2004 Glucocorticoid down-regulation of rat glucocorticoid receptor does not involve differential promoter regulation. J Endocrinol 183:365-374
    • (2004) J Endocrinol , vol.183 , pp. 365-374
    • Freeman, A.I.1    Munn, H.L.2    Lyons, V.3    Dammermann, A.4    Seckl, J.R.5    Chapman, K.E.6
  • 55
    • 0022543404 scopus 로고
    • Down-regulation of glucocorticoid receptor mRNA by glucocorticoid hormones and recognition by the receptor of a specific binding sequence within a receptor cDNA clone
    • Okret S, Poellinger L, Dong Y, Gustafsson JA 1986 Down-regulation of glucocorticoid receptor mRNA by glucocorticoid hormones and recognition by the receptor of a specific binding sequence within a receptor cDNA clone. Proc Natl Acad Sci USA 83:5899-5903
    • (1986) Proc Natl Acad Sci USA , vol.83 , pp. 5899-5903
    • Okret, S.1    Poellinger, L.2    Dong, Y.3    Gustafsson, J.A.4
  • 56
    • 0023235866 scopus 로고
    • Tissue-specific regulation of glucocorticoid receptor mRNA by dexamethasone
    • Kalinyak JE, Dorin RI, Hoffman AR, Perlman AJ 1987 Tissue-specific regulation of glucocorticoid receptor mRNA by dexamethasone. J Biol Chem 262:10441-10444
    • (1987) J Biol Chem , vol.262 , pp. 10441-10444
    • Kalinyak, J.E.1    Dorin, R.I.2    Hoffman, A.R.3    Perlman, A.J.4
  • 58
    • 0024204439 scopus 로고
    • Regulation of glucocorticoid receptor expression: Evidence for transcriptional and posttranslational mechanisms
    • Dong Y, Poellinger L, Gustafsson JA, Okret S 1988 Regulation of glucocorticoid receptor expression: evidence for transcriptional and posttranslational mechanisms. Mol Endocrinol 2:1256-1264
    • (1988) Mol Endocrinol , vol.2 , pp. 1256-1264
    • Dong, Y.1    Poellinger, L.2    Gustafsson, J.A.3    Okret, S.4
  • 61
    • 56749169163 scopus 로고    scopus 로고
    • A conserved molecular mechanism is responsible for the auto-up-regulation of glucocorticoid receptor gene promoters
    • Geng CD, Schwartz JR, Vedeckis WV 2008 A conserved molecular mechanism is responsible for the auto-up-regulation of glucocorticoid receptor gene promoters. Mol Endocrinol 22:2624-2642
    • (2008) Mol Endocrinol , vol.22 , pp. 2624-2642
    • Geng, C.D.1    Schwartz, J.R.2    Vedeckis, W.V.3
  • 62
    • 0034909433 scopus 로고    scopus 로고
    • Multiple promoters exist in the human GR gene, one of which is activated by glucocorticoids
    • Breslin MB, Geng CD, Vedeckis WV 2001 Multiple promoters exist in the human GR gene, one of which is activated by glucocorticoids. Mol Endocrinol 15:1381-1395
    • (2001) Mol Endocrinol , vol.15 , pp. 1381-1395
    • Breslin, M.B.1    Geng, C.D.2    Vedeckis, W.V.3
  • 63
    • 0032845245 scopus 로고    scopus 로고
    • Melatonin regulates glucocorticoid receptor: An answer to its antiapoptotic action in thymus
    • Sainz RM, Mayo JC, Reiter RJ, Antolin I, Esteban MM, Rodriguez C 1999 Melatonin regulates glucocorticoid receptor: an answer to its antiapoptotic action in thymus. FASEB J 13:1547-1556
    • (1999) FASEB J , vol.13 , pp. 1547-1556
    • Sainz, R.M.1    Mayo, J.C.2    Reiter, R.J.3    Antolin, I.4    Esteban, M.M.5    Rodriguez, C.6
  • 64
    • 27144490650 scopus 로고    scopus 로고
    • Leukemia inhibitory factor regulates glucocorticoid receptor expression in the hypothalamic-pituitary-adrenal axis
    • Kariagina A, Zonis S, Afkhami M, Romanenko D, Chesnokova V 2005 Leukemia inhibitory factor regulates glucocorticoid receptor expression in the hypothalamic-pituitary-adrenal axis. Am J Physiol Endocrinol Metab 289:E857-E863
    • (2005) Am J Physiol Endocrinol Metab , vol.289
    • Kariagina, A.1    Zonis, S.2    Afkhami, M.3    Romanenko, D.4    Chesnokova, V.5


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