Simvastatin and Ginkgo biloba in the treatment of subacute tinnitus: A retrospective study of 94 patients

American Journal of Otolaryngology - Head and Neck Medicine and Surgery

Volumn 32, Issue 1, 2011, Pages 19-23

  Canis, Martin ^a   Olzowy, Bernhard ^a   Welz, Christian ^a   Suckfüll, Markus ^a   Stelter, Klaus ^b  

^a LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

3 HYDROXY 3 METHYLGLUTARYL COENZYME A; CHOLESTEROL; GINKGO BILOBA EXTRACT; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LIPOPROTEIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; PLACEBO; SIMVASTATIN; TRIACYLGLYCEROL;

ADULT; ARTICLE; AUDIOMETRY; CHOLESTEROL BLOOD LEVEL; CLINICAL ASSESSMENT; CONTROLLED STUDY; DISEASE DURATION; FEMALE; GINKGO BILOBA; HUMAN; HYPERCHOLESTEROLEMIA; MAJOR CLINICAL STUDY; MALE; OUTCOME ASSESSMENT; PRIORITY JOURNAL; REMISSION; RETROSPECTIVE STUDY; SOUND INTENSITY; SUBACUTE TINNITUS; TINNITUS; TREATMENT DURATION;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ANALYSIS OF VARIANCE; AUDIOMETRY, PURE-TONE; FEMALE; GINKGO BILOBA; HUMANS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; HYPERCHOLESTEROLEMIA; MALE; MIDDLE AGED; PHYTOTHERAPY; PLANT PREPARATIONS; RETROSPECTIVE STUDIES; RISK FACTORS; SIMVASTATIN; TINNITUS; TREATMENT OUTCOME;

EID: 78649758913     PISSN: 01960709     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.amjoto.2009.09.004     Document Type: Article

References (17)

1. Miller J.M., Ren T.Y., and Nuttall A.L. Studies of inner ear blood flow in animals and human beings Otolaryngol Head Neck Surg 112 1995 101 113
2. Sidman J.D., Prazma J., and Pulver S.H. Cochlea and heart as end-organs in small vessel disease Ann Otol Rhinol Laryngol 97 1988 9 13
3. Saito T., Sato K., and Saito H. An experimental study of auditory dysfunction associated with hyperlipoproteinemia Arch Otorhinolaryngol 243 1986 242 245
4. Gratton M.A., and Wright C.G. Alterations of inner ear morphology in experimental hypercholesterolemia Hear Res 61 1992 97 105
5. Feron O., Dessy C., and Desager J.P. Hydroxy-methylglutaryl-coenzyme A reductase inhibition promotes endothelial nitric oxide synthase activation through a decrease in caveolin abundance Circulation 103 2001 113 118
6. Nguyen T.V., and Brownell W.E. Contribution of membrane cholesterol to outer hair cell lateral wall stiffness Otolaryngol Head Neck Surg 119 1998 14 20
7. Canis M., Schmid J., and Olzowy B. The influence of cholesterol on the motility of cochlear outer hair cells and the motor protein prestin Acta Otolaryngol 2009 [electronic publication ahead of print]
8. Suckfull M. Fibrinogen and LDL apheresis in treatment of sudden hearing loss: a randomised multicentre trial Lancet 360 2002 1811 1817
9. Renders L., Mayer-Kadner I., and Koch C. Efficacy and drug interactions of the new HMG-CoA reductase inhibitors cerivastatin and atorvastatin in CsA-treated renal transplant recipients Nephrol Dial Transplant 16 2001 141 146
10. Brechtelsbauer P.B., Nuttall A.L., and Miller J.M. Basal nitric oxide production in regulation of cochlear blood flow Hear Res 77 1994 38 42
11. Fessenden J.D., and Schacht J. The nitric oxide/cyclic GMP pathway: a potential major regulator of cochlear physiology Hear Res 118 1998 168 176
12. Joyce N.C., Haire M.F., and Palade G.E. Contractile proteins in pericytes. I. Immunoperoxidase localization of tropomyosin J Cell Biol 100 1985 1379 1386
13. Dujovne C.A., Harris W.S., and Altman R. Effect of atorvastatin on hemorheologic-hemostatic parameters and serum fibrinogen levels in hyperlipidemic patients Am J Cardiol 85 2000 350 353
14. Drew S., and Davies E. Effectiveness of Ginkgo biloba in treating tinnitus: double blind, placebo controlled trial BMJ 322 2001 73
15. Rejali D., Sivakumar A., and Balaji N. Ginkgo biloba does not benefit patients with tinnitus: a randomized placebo-controlled double-blind trial and meta-analysis of randomized trials Clin Otolaryngol Allied Sci 29 2004 226 231
16. Goebel G., and Hiller W. The tinnitus questionnaire. A standard instrument for grading the degree of tinnitus. Results of a multicenter study with the tinnitus questionnaire HNO 42 1994 166 172
17. Olzowy B., Canis M., and Hempel J.M. Effect of atorvastatin on progression of sensorineural hearing loss and tinnitus in the elderly: results of a prospective, randomized, double-blind clinical trial Otol Neurotol 28 2007 455 458