A quantitative estimation of 14-deoxy-11, 12-didehydroandrographolide in Andrographis paniculata by HPTLC

International Journal of Pharmacy and Pharmaceutical Sciences

Volumn 2, Issue SUPPL. 4, 2010, Pages 49-52

  Kapadi, C ^a   Patel, B ^a   Katkar, K ^b   Suthar, A ^b   Chauhan, V S ^a  

^a RAMNARAIN RUIA COLLEGE   (India)

^b Piramal Enterprises Limited   (India)

Author keywords

12 didehydroandrographolide; 14 deoxy 11; A paniculata; HPTLC

Indexed keywords

11,12 DIDEHYDRO 14 DEOXYANDROGRAPHOLIDE; ANDROGRAPHIS PANICULATA EXTRACT; ANDROGRAPHOLIDE; IMMUNOSTIMULATING AGENT; UNCLASSIFIED DRUG;

ACCURACY; ANDROGRAPHIS PANICULATA; ARTICLE; CONTROLLED STUDY; DRUG DETERMINATION; DRUG STABILITY; HIGH PERFORMANCE THIN LAYER CHROMATOGRAPHY; QUANTITATIVE ANALYSIS; RELIABILITY; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY; STANDARDIZATION; VALIDATION PROCESS;

EID: 78649749099     PISSN: 09751491     EISSN: 09751491     Source Type: Journal    
DOI: None     Document Type: Article

References (23)

1. Kapil A, Koul IB, Banerjee SK and Gupta BD. Antihepatotoxic effects of major diterpenoid constituents of Andrographis paniculata. Biochemical pharmacology., 1993, 6(1): 182-185.
2. Handa SS, Sharma A. Hepatoprotective activity of andrographolide from Andrographis paniculata against carbontetrachloride. Indian J Med Res 1990; 92: 276-283.
3. Kamble MB, Dumbre RK, Rangari VD. Hepatoprotective activity studies of herbal formulations. Int J Green Pharm 2008; 2:147-151.
4. Kanokwan Jarukamjorn, Kannika Don-in, Cattaleya Makejaruskul, Thewarac, Impact of Andrographis paniculata crude extract on mouse hepatic cytochrome P450 enzymes. 1998; 60(3): 176-178.
5. Mishra US, Mishra A, Kumari R, Murthy PN, Naik BS. Antibacterial activity of ethanol extract of Andrographis paniculata. Indian J Pharm Sci 2009; 71:436-438.
6. Dua VK, Ojha VP, Roy R, Joshi B C, Valecha N, Usha Devi, Bhatnagar MC, Sharma VP and Subbarao SK, Anti-malarial activity of some xanthones isolated from the roots of Andrographis paniculata, Journal of Ethnopharmacology 2004; 95(2-3): 247-251.
7. Bagchi P, Mahesh M, Somashekhar R. Pharmaco-Informatics: Homology Modelling of the Target Protein (GP1, 2) for Ebola Hemorrhagic Fever and Predicting an Ayurvedic Remediation of the Disease. J Proteomics Bioinform 2009; 2: 287-294.
8. Huang KC, The pharmacology of Chinese herbs, 2nd edition, CRC press LLC; 1999: 293-294.
9. Liu J, Wang ZT, Ji LL. In vivo and in vitro anti-inflammatory activities of neoandrographolide, Am J Chin Med. 2007; 35(2):317-328.
10. Alagesaboopathi, Ethnomedicinal plants and their utilization by villagers in Kumaragiri hills of Salem district of Tamilnadu, India, Afr. J. Trad. CAM 2009; 6 (3): 222-227.
11. Lin FL, Wu SJ, Lee SC et al, Antioxidant, antioedema and analgesic activities of Andrographis paniculata extracts and their active constituent andrographolide. Phytother Res. 2009; 23(7):958-964.
12. Raj RK. Screening of indigenous plants for anthelmintic action against human Ascaris lumbricoides: Part--2. Indian J Physiol Pharmacol 1975; 19(1)
13. Meenatchisundaram S, Parameswari G, Michael Studies on antivenom activity of Andrographis paniculata and Aristolochia indica plant extracts against Daboia russelli venom by in vivo and invitro methods. Indian Journal of Science and Technology 2009. 2 (4), 76-79.
14. Raina AP, Kumar A, Pareek S K. HPTLC analysis of hepatoprotective diterpenoid andrographolide from Andrographis paniculata Nees (kalmegh). Indian J Pharm Sci 2007; 69: 473-475.
15. Zhang CY, Tan BKH. Mechanisms of cardiovascular activity of Andrographis paniculata in the anaesthetized rat, Journal of Ethnopharmacology, 1997; 56(2), 97-101.
16. Borhanuddin M, Shamsuzzoha M, Hussain AH. Hypoglycaemic effects of Andrographis paniculata Nees on non-diabetic rabbits. Bangladesh Med Res Counc Bull 1994; 20(1):24-26.
17. Yu BC, Hung CR, Chen WC, et al. Antihyperglycemic effect of andrographolide in streptozotocin-induced diabetic rats. Planta Med 2003; 69(12):1075-1079.
18. Calabrese C, Berman SH, Babish JG, et al. A phase I trial of andrographolide in HIV positive patients and normal volunteers. Phytother Res 2000; 14(5):333-338.
19. Suebsasana S, Pongnaratn P, Sattayasai J, Arkaravichien T et al. Analgesic, antipyretic, anti-inflammatory and toxic effects of andrographolide derivatives in experimental animals, Archives of Pharmacal Research 2009, 32, 1191-1200.
20. Yoopan N, Thisoda P, Rangkadilok N, Sahasitiwat S, Pholphana N, Ruchirawat S, Satayavivad J,Cardiovascular effects of 14-deoxy-11,12-didehydroandrographolide and Andrographis paniculata extracts. Planta Med. 2007; 73(6): 503-511.
21. Puri A, Saxena R, Saxena RP, Saxena KC et al. Immunostimulant agents from Andrographis paniculata. J Nat Prod. 1993; 56(7): 995-997.
22. Saxena S, Jain DC, Gupta MM, Bhakuni RS et al. High-Performance Thin-Layer Chromatographic Analysis of Hepatoprotective diterpenoids from Andrographis paniculata. Phytochem. Anal. 2000; 11, 34-36.
23. Jain DC, Gupta MM., Saxena S, Kumar S., LC analysis of hepatoprotective diterpenoids from Andrographis paniculata, Journal of Pharmaceutical and Biomedical Analysis 2000; 22:705-709.