Ion mobility mass spectrometry of two tetrameric membrane protein complexes reveals compact structures and differences in stability and packing

Journal of the American Chemical Society

Volumn 132, Issue 44, 2010, Pages 15468-15470

  Wang, Sheila C ^a   Politis, Argyris ^a   Di Bartolo, Natalie ^b   Bavro, Vassiliy N ^a   Tucker, Stephen J ^a   Booth, Paula J ^b   Barrera, Nelson P ^c   Robinson, Carol V ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF BRISTOL   (United Kingdom)

^c PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE   (Chile)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION CONDITIONS; BULK WATER; COLLISION CROSS SECTIONS; COMPACT STRUCTURES; DRUG BINDING; GAS-PHASE STRUCTURES; GASPHASE; ION CHANNEL; ION MOBILITY-MASS SPECTROMETRY; MEMBRANE PROTEIN COMPLEX; QUATERNARY STRUCTURE; STRUCTURAL CHANGE; TRANSMEMBRANES;

BIOLOGICAL MEMBRANES; MASS SPECTROMETRY; PROTEINS; SOAPS (DETERGENTS);

IONS;

DETERGENT; ION CHANNEL; MEMBRANE PROTEIN; PROTEIN SUBUNIT; TETRAMER; TRANSPORTER ASSOCIATED WITH ANTIGEN PROCESSING 1;

ARTICLE; ION MOBILITY SPECTROMETRY; MASS SPECTROMETRY; MICELLE; PROTEIN BINDING; PROTEIN LOCALIZATION; PROTEIN QUATERNARY STRUCTURE; PROTEIN STABILITY; PROTEIN STRUCTURE;

GASES; MASS SPECTROMETRY; MEMBRANE PROTEINS; MODELS, MOLECULAR; MULTIPROTEIN COMPLEXES; PROTEIN SUBUNITS;

EID: 78649748259     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja104312e     Document Type: Article

References (12)

1. Barrera, N. P., Di Bartolo, N., Booth, P. J., and Robinson, C. V. Science 2008, 321, 243-246
2. Barrera, N. P., Isaacson, S. C., Zhou, M., Bavro, V. N., Welch, A., Schaedler, T. A., Seeger, M. A., Miguel, R. N., Korkhov, V. M., van Veen, H. W., Venter, H., Walmsley, A. R., Tate, C. G., and Robinson, C. V. Nat. Methods 2009, 6, 585-587
3. Gulbis, J. M., Kuo, A., Smith, B., Doyle, D. A., Edwards, A., Arrowsmith, C., and Sundstrom, M. Unpublished data, 2005.
4. Locher, K. P., Lee, A. T., and Rees, D. C. Science 2002, 296, 1091-1098
5. Ruotolo, B. T., Giles, K., Campuzano, I., Sandercock, A. M., Bateman, R. H., and Robinson, C. V. Science 2005, 310, 1658-1661
6. Ruotolo, B. T., Hyung, S. J., Robinson, P. M., Giles, K., Bateman, R. H., and Robinson, C. V. Angew. Chem., Int. Ed. 2007, 46, 8001-8004
7. Hoaglund-Hyzer, C. S., Counterman, A. E., and Clemmer, D. E. Chem. Rev. 1999, 99, 3037-3080
8. Bernstein, S. L., Liu, D., Wyttenbach, T., Bowers, M. T., Lee, J. C., Gray, H. B., and Winkler, J. R. J. Am. Soc. Mass Spectrom. 2004, 15, 1435-1443
9. Kaddis, C. S., Lomeli, S. H., Yin, S., Berhane, B., Apostol, M. I., Kickhoefer, V. A., Rome, L. H., and Loo, J. A. J. Am. Soc. Mass Spectrom. 2007, 18, 1206-1216
10. Ruotolo, B. T., Benesch, J. L. P., Sandercock, A. M., Hyung, S. J., and Robinson, C. V. Nat. Protoc. 2008, 3, 1139-1152
11. Light-Wahl, K. J., Schwartz, B. L., and Smith, R. D. J. Am. Chem. Soc. 1994, 116, 5271-5278
12. Le Coutre, J., Kaback, H. R., Patel, C. K. N., Heginbotham, L., and Miller, C. Proc. Natl. Acad. Sci. U.S.A. 1998, 95, 6114-6117