Suppression of nitric oxide synthesis by L-NAME reverses the beneficial effects of pioglitazone on scopolamine-induced memory impairment in mice

European Journal of Pharmacology

Volumn 650, Issue 1, 2011, Pages 240-248

  Allami, Nika ^a,b   Javadi Paydar, Mehrak ^a,c   Rayatnia, Farhoud ^b   Sehhat, Kourosh ^b   Rahimian, Reza ^b   Norouzi, Abbas ^c   Dehpour, Ahmad Reza ^a  

^a TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

(Mice); L NAME; Nitric oxide; Pioglitazone; Spatial recognition memory

Indexed keywords

N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; PIOGLITAZONE; SCOPOLAMINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; COGNITIVE DEFECT; CONTROLLED STUDY; DRUG EFFECT; MAZE TEST; MEMORY CONSOLIDATION; MEMORY DISORDER; MOUSE; NONHUMAN; PASSIVE AVOIDANCE; PRIORITY JOURNAL; SPATIAL MEMORY;

ANIMALS; DRUG INTERACTIONS; MAZE LEARNING; MEMORY DISORDERS; MEMORY, SHORT-TERM; MICE; MOTOR ACTIVITY; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; SCOPOLAMINE; SIGNAL TRANSDUCTION; THIAZOLIDINEDIONES;

EID: 78649722214     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2010.10.007     Document Type: Article

References (48)

1. T. Abel, and K.M. Lattal Molecular mechanisms of memory acquisition, consolidation and retrieval Curr. Opin. Neurobiol. 11 2001 180 187
2. M. Anjaneyulu, and P. Ramarao Protective effect of pioglitazone against multiple low-dose streptozotocin-induced diabetes in rats Meth. Find. Exp. Clin. Pharmacol. 25 2003 205 208
3. J. Berger, and D.E. Moller The mechanisms of action of PPARs Annu. Rev. Med. 53 2002 409 435
4. A. Blokland Acetylcholine: a neurotransmitter for learning and memory? Brain Res. Rev. 21 1996 285 300
5. G.A. Bohme, C. Bon, M. Lemaire, M. Reibaud, O. Piot, J.M. Stutzmann, A. Doble, and J.C. Blanchard Altered synaptic plasticity and memory formation in nitric oxide synthase inhibitor-treated rats Proc. Natl Acad. Sci. USA 90 1993 9191 9194
6. D.M. Bowen, C.B. Smith, P. White, and A.N. Davison Neurotransmitter- related enzymes and indices of hypoxia in senile dementia and other abiotrophies Brain 99 1976 459 496
7. P.F. Chapman, C.M. Atkins, M.T. Allen, J.E. Haley, and J.E. Steinmetz Inhibition of nitric oxide synthesis impairs two different forms of learning NeuroReport 3 1992 567 570
8. D.H. Cho, Y.J. Choi, S.A. Jo, and I. Jo Nitric oxide production and regulation of endothelial nitric-oxide synthase phosphorylation by prolonged treatment with troglitazone: evidence for involvement of peroxisome proliferator-activated receptor (PPAR) gamma-dependent and PPARgamma-independent signaling pathways J. Biol. Chem. 279 2004 2499 2506
9. M. Collino, M. Aragno, R. Mastrocola, M. Gallicchio, A.C. Rosa, C. Dianzani, O. Danni, C. Thiemermann, and R. Fantozzi Modulation of the oxidative stress and inflammatory response by PPAR-gamma agonists in the hippocampus of rats exposed to cerebral ischemia/reperfusion Eur. J. Pharmacol. 530 2006 70 80
10. C.K. Combs, D.E. Johnson, J.C. Karlo, S.B. Cannady, and G.E. Landreth Inflammatory mechanisms in Alzheimer's disease: inhibition of beta-amyloidstimulated proinflammatory responses and neurotoxicity by PPARgamma agonists J. Neurosci. 20 2000 558 567
11. F. Dellu, W. Mayo, J. Cherkaoui, M. Le Moal, and H. Simon A two-trial memory task with automated recording: Study in young and aged rats Brain Res. 588 1992 132 139
12. B.D. Devan, P.J. Pistell, L.W. Daffin Jr., C.M. Nelson, K.B. Duffy, J.L. Bowker, I.S. Bharati, D. Sierra-Mercado, E.L. Spangler, and D.K. Ingram Sildenafil citrate attenuates a complex maze impairment induced by intracerebroventricular infusion of the NOS inhibitor Nomeganitro-L-arginine methyl ester Eur. J. Pharmacol. 563 2007 134 140
13. D.L. Feinstein, A. Spagnolo, C. Akar, G. Weinberg, P. Murphy, V. Gavrilyuk, and C. Dello Russo Receptor-independent actions of PPAR thiazolidinedione agonists: is mitochondrial function the key? Biochem. Pharmacol. 70 2005 177 188
14. J. Garthwaite Glutamate, nitric oxide and cell-cell signalling in the nervous system Trends Neurosci. 14 1991 60 67
15. J.E. Haley, G.L. Wilcox, and P.F. Chapman The role of nitric oxide in hippocampal long-term potentiation Neuron 8 1992 211 216
16. H. Hanyu, T. Sato, A. Kiuchi, H. Sakurai, and T. Iwamoto Pioglitazone improved cognition in a pilot study on patients with Alzheimer's disease and mild cognitive impairment with diabetes mellitus J. Am. Geriatr. Soc. 57 2009 177 179
17. M.T. Heneka, T. Klockgether, and D.L. Feinstein Peroxisome proliferator-activated receptor-gamma ligands reduce neuronal inducible nitric oxide synthase expression and cell death in vivo J. Neurosci. 20 2000 6862 6867
18. M.T. Heneka, M. Sastre, L. Dumitrescu-Ozimek, A. Hanke, I. Dewachter, C. Kuiperi, K. O'Banion, T. Klockgether, F. Van Leuven, and G.E. Landreth Acute treatment with the PPARgamma agonist pioglitazone and ibuprofen reduces glial inflammation and Abeta1-42 levels in APPV717I transgenic mice Brain 128 2005 1442 1453
19. A.M. Huang, and E.H. Lee Role of hippocampal nitric oxide in memory retention in rats Pharmacol. Biochem. Behav. 50 1995 327 332
20. R.L. Hunter, D.Y. Choi, S.A. Ross, and G. Bing Protective properties afforded by pioglitazone against intrastriatal LPS in Sprague-Dawley rats Neurosci. Lett. 432 2008 198 201
21. T. Kainu, A.C. Wikström, J.A. Gustafsson, and M. Pelto-Huikko Localization of the peroxisome proliferator-activated receptor in the brain NeuroReport 5 1994 2481 2485
22. B. Kaur, N. Singh, and A.S. Jaggi Exploring mechanism of pioglitazone-induced memory restorative effect in experimental dementia Fundam. Clin. Pharmacol. 23 2009 557 566
23. M.J. Kim, S.J. Choi, S.T. Lim, H.K. Kim, Y.J. Kim, H.G. Yoon, and D.H. Shin Zeatin supplement improves scopolamine-induced memory impairment in mice Biosci. Biotechnol. Biochem. 72 2008 577 581
24. M.D. Kopelman, and T.H. Corn Cholinergic 'blockade' as a model for cholinergic depletion. A comparison of the memory deficits with those of Alzheimer-type dementia and the alcoholic Korsakoff syndrome Brain 111 1988 1079 1110
25. P. Kumar, R.K. Kaundal, S. More, and S.S. Sharma Beneficial effects of pioglitazone on cognitive impairment in MPTP model of Parkinson's disease Behav. Brain Res. 197 2009 398 403
26. G. Landreth Therapeutic use of agonists of the nuclear receptor PPARgamma in Alzheimer's disease Curr. Alzheimer Res. 4 2007 159 164
27. D.J. Loane, A. Pocivavsek, C.E. Moussa, R. Thompson, Y. Matsuoka, A.I. Faden, G.W. Rebeck, and M.P. Burns Amyloid precursor protein secretases as therapeutic targets for traumatic brain injury Nat. Med. 15 2009 377 379
28. T. Matsumoto, E. Noguchi, T. Kobayashi, and K. Kamata Mechanisms underlying the chronic pioglitazone treatment-induced improvement in the impaired endothelium-dependent relaxation seen in aortas from diabetic rats Free Radic. Biol. Med. 42 2007 993 1007
29. C.R. Meyer, E.L. Spangler, N. Patel, E.D. London, and D.K. Ingram Impaired learning in rats in a 14-unit T-maze by 7-nitroindazole, a neuronal nitric oxide synthase inhibitor, is attenuated by the nitric oxide donor, molsidomine Eur. J. Pharmacol. 341 1998 17 22
30. P.D. Miles, O.M. Romeo, K. Higo, A. Cohen, K. Rafaat, and J.M. Olefsky TNFalpha-induced insulin resistance in vivo and its prevention by troglitazone Diabetes 46 1997 1678 1683
31. S. Moncada, R.M.J. Palmer, and E.A. Higgs Nitric oxide: physiology, pathophysiology, and pharmacology Pharmacol. Rev. 43 1991 109 123
32. S. Moreno, S. Farioli-Vecchioli, and M.P. Cerù Immunolocalization of peroxisome proliferator-activated receptors and retinoid X receptors in the adult rat CNS Neuroscience 123 2004 131 145
33. Y. Noda, K. Yamada, and T. Nabeshima Role of nitric oxide in the effect of aging on spatial memory in rats Behav. Brain Res. 83 1997 153 158
34. T.J. O'Dell, R.D. Hawkins, E.R. Kandel, and O. Arancio Tests of the roles of two diffusible substances in long-term potentiation: evidence for nitric oxide as a possible early retrograde messenger Proc. Natl Acad. Sci. USA 88 1991 11285 11289
35. T. Pancani, J.T. Phelps, J.L. Searcy, M.W. Kilgore, K.C. Chen, N.M. Porter, and O. Thibault Distinct modulation of voltage-gated and ligand-gated Ca2+ currents by PPAR-gamma agonists in cultured hippocampal neurons J. Neurochem. 109 2009 1800 1811
36. A.R. Pathan, B. Viswanad, S.K. Sonkusare, and P. Ramarao Chronic administration of pioglitazone attenuates intracerebroventricular streptozotocin induced-memory impairment in rats Life Sci. 79 2006 2209 2216
37. H.A. Pershadsingh, M.T. Heneka, R. Saini, N.M. Amin, D.J. Broeske, and D.L. Feinstein Effect of pioglitazone treatment in a patient with secondary multiple sclerosis J. Neuroinflammation 1 2004 3
38. C. Romera, O. Hurtado, J. Mallolas, M.P. Pereira, J.R. Morales, A. Romera, J. Serena, J. Vivancos, F. Nombela, P. Lorenzo, I. Lizasoain, and M.A. Moro Ischemic preconditioning reveals that GLT1/EAAT2 glutamate transporter is a novel PPARgamma target gene involved in neuroprotection J. Cereb. Blood Flow Metab. 27 2007 1327 1338
39. R. Stevens Scopolamine impairs spatial maze performance in rats Physiol. Behav. 27 1981 385 386 (Pubitemid 11019326)
40. S. Sundararajan, Q. Jiang, M. Heneka, and G. Landreth PPARgamma as a therapeutic target in central nervous system diseases Neurochem. Int. 49 2006 136 144
41. A.J. Susswein, A. Katzoff, N. Miller, and I. Hurwitz Nitric oxide and memory Neuroscientist 10 2004 153 162
42. S.E. Tan Roles of hippocampal nitric oxide and calcium/ calmodulindependent protein kinase II in inhibitory avoidance learning in rats Behav. Pharmacol. 18 2007 29 38
43. K. Tanaka, T. Yagi, R. Shimakoshi, K. Azuma, T. Nanba, H. Ogo, A. Tamura, and M. Asanuma Effects of galantamine on L-NAME-induced behavioral impairment in Y-maze task in mice Neurosci. Lett. 462 2009 235 238
44. G.S. Watson, B.A. Cholerton, M.A. Reger, L.D. Baker, S.R. Plymate, S. Asthana, M.A. Fishel, J.J. Kulstad, P.S. Green, D.G. Cook, S.E. Kahn, M.L. Keeling, and S. Craft Preserved cognition in patients with early Alzheimer disease and amnestic mild cognitive impairment during treatment with rosiglitazone: a preliminary study Am. J. Geriatr. Psychiatry 13 2005 950 958
45. P.J. Whitehouse, D.L. Price, R.G. Struble, A.W. Clark, J.T. Coyle, and M.R. Delon Alzheimer's disease and senile dementia: loss of neurons in the basal forebrain Science 215 1982 1237 1239
46. K. Yamada, Y. Noda, S. Nakayama, Y. Komori, H. Sugihara, T. Hasegawa, and T. Nabeshima Role of nitric oxide in learning and memory and in monoamine metabolism in the rat brain Br. J. Pharmacol. 115 1995 852 858
47. K. Yamada, M. Hiramatsu, Y. Noda, T. Mamiya, M. Murai, T. Kameyama, Y. Komori, T. Nikai, H. Sugihara, and T. Nabeshima Role of nitric oxide and cyclic GMP in the dizocilpine-induced impairment of spontaneous alternation behavior in mice Neuroscience 74 1996 365 374 (Pubitemid 26274208)
48. Q. Yan, J. Zhang, H. Liu, S. Babu-Khan, R. Vassar, A.L. Biere, M. Citron, and G. Landreth Anti-inflammatory drug therapy alters beta-amyloid processing and deposition in an animal model of Alzheimer's disease J. Neurosci. 23 2003 7504 7509